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Youngnam Jin
Immunology and Metabolion
Wuhan University
Hubei
Language: English, Chinese, Korean
Drug Discovery
Chemical Genetics
Molecular Biology
Therapeutics
Disease Mechanisms
Biomedical Research
Target Identification
Cellular Processes
Gene Regulation
Clinical Applications
Areas of Focus
- Drug screening and chemical biology
- Developmental biology
- Cancer biology
- RNA biology
Work Experience
- 2011-2017 - Massachusetts General Hospital, USA - Postdoctoral Research Fellow
- 2018 - University of Utah, USA - Research Assistant Professor
- 2018-present - Wuhan University Medical Research Institute, China - Professor
Academic Background & Achievements
- 1990-1997 Bachelor: Inha University, South Korea
- 1997-1999 Master: Seoul National University, South Korea
- 2003-2010 PhD: University of Rochester, USA
Publications
- Chemical Genetics: Manipulating the Germline with Small Molecules, Jin YN and Peterson RT, 2021
- Non-canonical translation via deadenylated 3’UTRs maintains primordial germ cells, Jin YN et al., 2018
- Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin, Jin YN et al., 2013
- An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action, Jin S et al., 2013
- Usp14 deficiency increases Tau phosphorylation without altering tau degradation or causing tau-dependent deficits, Jin YN et al., 2012
- Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ, Jin YN et al., 2012
- Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356, Dolan PJ, Jin YN et al., 2011
- The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease, Jin YN and Johnson GVW, 2010
Awards
- 2021: Foreign Young Talent
