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Bing Wu
Immunology and Metabolion
Wuhan University
Hubei
Language: Chinese, English
Immunology
T-Cells
Autoimmune Diseases
Antiviral Responses
Immune Cells
Pathological Conditions
Metabolic Syndromes
Cell Differentiation
Immune Regulation
Therapeutic Strategies
Areas of Focus
- Immunology, especially T-cell immunity
- Mechanisms determining the fate of immune cells
- Role of T-cells in autoimmune diseases and antiviral responses
- Regulation of immune and metabolic syndromes under normal and pathological conditions
Work Experience
- 2014.9-2019.9 Postdoctoral Researcher, University of North Carolina at Chapel Hill
- 2019.9-2021.2 Assistant Researcher, University of North Carolina at Chapel Hill
- 2021.3-present Professor, Wuhan University Medical Research Institute/Center for Advanced Studies in Immunology and Metabolism
- 2022.1-present Professor, Wuhan University Zhongnan Hospital Medical Research Institute
Academic Background & Achievements
- 2005-2009 Bachelor of Animal Science: Jilin University College of Animal Science and Technology
- 2009-2014 Ph.D. in Microbiology and Immunology: China Agricultural University College of Biology
Publications
- Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells, Kiapour N, Wu B, Yan Wang…Wan YY, Markovic-Plese S, 2022
- The TGF-b superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation, Wu, B., Zhang S., Guo Z., Bi Y., Zhou M., Li P., Seyedsadr M., Xu X., Li J., Markovic-Plese S., Wan YY, 2021
- The SKI proto-oncogene restrains the resident CD103+CD8+ T cell response in viral clearance, Wu, B., Zhang G., Guo Z., Wang G., Xu X., …Zheng J., Wan YY, 2021
- Molecular control of pathogenic Th17 cells in autoimmune diseases, Wu B., Wan Y., 2020
- RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs, Wu, B., Zhang, S., Guo, Z., Wang, G., Zhang, G., Xie, L., Lou, J., Chen, X., Wu, D., Bergmeier, W., Zheng J., Wan YY, 2018
- BPTF Is Essential for T Cell Homeostasis and Function, Wu B, Wang Y, Wang C, Wang GG, Wu J, Wan YY, 2016
- Herpes Simplex Virus 1 Suppresses the Function of Lung Dendritic Cells via Caveolin-1, Wu B, Geng S, Bi Y, Liu H, Hu Y, Li X, Zhang Y, Zhou X, Zheng G, He B, Wang B, 2015
- Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice, Wu B, Zou Q, Hu Y, Wang B, 2013
- DCAF1 regulates Treg senescence via the ROS axis during immunological ageing, Guo, Z., Wang, G., Wu, B., Chou, W.C., Cheng, L., Zhou, C., Lou, J., Wu, D., Su, L., Zheng, J., et al., 2020
- Critical role of regulatory T cells in the latency and stress-induced reactivation of HSV-1, Yu W, Geng S, Suo Y, Wei X, Cai Q, Wu B, Zhou X, Shi Y, Wang B, 2018
- Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation, Zhang, S., Takaku, M., Zou, L., Gu, A.D., Chou, W.C., Zhang, G., Wu, B., Kong, Q., Thomas, S.Y., Serody, J.S., et al., 2017
- CD8+ Treg cells suppress CD8+ T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection, Zou Q, Wu B, Xue J, Fan X, Feng C, Geng S, Wang M, Wang B, 2014
Awards
- Dupont First Prize of Scholarship Award, Dupont Company, 2013
- Excellent Scientific Reward by China Agricultural University, 2012-2013
- Wuhan Talent - Innovative Talent, 2021
- Hubei Province 'Bairen Plan' (Innovative Talent), 2021
