Professor | Wanbao Niu | Asia Growth Partners

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Name	Wanbao Niu
Contact Information	niuwanbao@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Wanbao Niu

Contact Information

niuwanbao@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005/09-2009/06 Bachelor in Biological Sciences, China Agricultural University 2009/09-2016/06 PhD in Animal Physiology, China Agricultural University
Work Experience	2016/10-2023/12 Postdoctoral Researcher, Carnegie Institute for Science, Department of Embryology (HHMI) 2024/01-present Professor, Wuhan University, Taikang Medical College (Basic Medical College) 2024/01-present Principal Investigator, Wuhan University, Taikang Life Science Center
Awards	National Talent Program Awardee

University/Lab Affiliation and Title

Wuhan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2005/09-2009/06 Bachelor in Biological Sciences, China Agricultural University
2009/09-2016/06 PhD in Animal Physiology, China Agricultural University

Work Experience

2016/10-2023/12 Postdoctoral Researcher, Carnegie Institute for Science, Department of Embryology (HHMI)
2024/01-present Professor, Wuhan University, Taikang Medical College (Basic Medical College)
2024/01-present Principal Investigator, Wuhan University, Taikang Life Science Center

Awards

National Talent Program Awardee

Areas of Focus	Formation and developmental regulation of mammalian primordial follicles
Publications	Mouse oocytes develop in cysts with the help of nurse cells, Niu, W., & Spradling, A. C., 2022 Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary, Niu, W., & Spradling, A. C., 2020 JNK signaling regulates E-cadherin junctions in germline cysts and determines primordial follicle formation in mice, Niu, W., Wang, Y., Wang, Z., Xin, Q., Wang, Y., Feng, L., Zhao, L., Wen, J., Zhang, H., Wang, C., & Xia, G., 2016 Gene X, a key gene for communication between supporting cells and germ cells, Niu, W., & Spradling, A. C., 2023 Cdc42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes, Yan, H., Zhang, J., Wen, J., Wang, Y., Niu, W., Teng, Z., Zhao, T., Dai, Y., Zhang, Y., Wang, C., Qin, Y., Xia, G., & Zhang, H., 2018 ADAM10-notch signaling governs the recruitment of ovarian pregranulosa cells and controls folliculogenesis in mice, Feng, L., Wang, Y., Cai, H., Sun, G., Niu, W., Xin, Q., Tang, X., Zhang, J., Wang, C., Zhang, H., & Xia, G., 2016 Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice, Zhao, L., Du, X., Huang, K., Zhang, T., Teng, Z., Niu, W., Wang, C., & Xia, G. Gap junctions are essential for murine primordial follicle assembly immediately before birth, Teng, Z., Wang, C., Wang, Y., Huang, K., Xiang, X., Niu, W., Feng, L., Zhao, L., Yan, H., & Zhang, H., 2016 Follistatin288 regulates germ cell cyst breakdown and primordial follicle assembly in the mouse ovary, Wang, Z., Niu, W., Wang, Y., Teng, Z., Wen, J., Xia, G., & Wang, C., 2015 Cyclic AMP in oocytes controls meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary, Wang, Y., Teng, Z., Li, G., Mu, X., Wang, Z., Feng, L., Niu, W., Huang, K., Xiang, X., Wang, C., Zhang, H., & Xia, G., 2015 S100A8, an oocyte-specific chemokine, directs the migration of ovarian somatic cells during mouse primordial follicle assembly, Teng, Z., Wang, C., Wang, Y., Huang, K., Xiang, X., Niu, W., Feng, L., Zhao, L., Yan, H., Zhang, H., & Xia, G., 2015 Transforming growth factor-β signaling participates in the maintenance of the primordial follicle pool in the mouse ovary, Wang, Z.-P., Mu, X.-Y., Guo, M., Wang, Y.-J., Teng, Z., Mao, G.-P., Niu, W.-B., Feng, L.-Z., Zhao, L.-H., & Xia, G.-L., 2014 Effect of different culture systems and 3, 5, 3'-triiodothyronine/follicle-stimulating hormone on preantral follicle development in mice, Zhang, C., Wang, X., Wang, Z., Niu, W., Zhu, B., & Xia, G., 2013 The effect of gonadotropin on glucose transport and apoptosis in rat ovary, Zhang, C., Niu, W., Wang, Z., Wang, X., & Xia, G., 2012

Areas of Focus

Formation and developmental regulation of mammalian primordial follicles

Publications

Mouse oocytes develop in cysts with the help of nurse cells, Niu, W., & Spradling, A. C., 2022
Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary, Niu, W., & Spradling, A. C., 2020
JNK signaling regulates E-cadherin junctions in germline cysts and determines primordial follicle formation in mice, Niu, W., Wang, Y., Wang, Z., Xin, Q., Wang, Y., Feng, L., Zhao, L., Wen, J., Zhang, H., Wang, C., & Xia, G., 2016
Gene X, a key gene for communication between supporting cells and germ cells, Niu, W., & Spradling, A. C., 2023
Cdc42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes, Yan, H., Zhang, J., Wen, J., Wang, Y., Niu, W., Teng, Z., Zhao, T., Dai, Y., Zhang, Y., Wang, C., Qin, Y., Xia, G., & Zhang, H., 2018
ADAM10-notch signaling governs the recruitment of ovarian pregranulosa cells and controls folliculogenesis in mice, Feng, L., Wang, Y., Cai, H., Sun, G., Niu, W., Xin, Q., Tang, X., Zhang, J., Wang, C., Zhang, H., & Xia, G., 2016
Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice, Zhao, L., Du, X., Huang, K., Zhang, T., Teng, Z., Niu, W., Wang, C., & Xia, G.
Gap junctions are essential for murine primordial follicle assembly immediately before birth, Teng, Z., Wang, C., Wang, Y., Huang, K., Xiang, X., Niu, W., Feng, L., Zhao, L., Yan, H., & Zhang, H., 2016
Follistatin288 regulates germ cell cyst breakdown and primordial follicle assembly in the mouse ovary, Wang, Z., Niu, W., Wang, Y., Teng, Z., Wen, J., Xia, G., & Wang, C., 2015
Cyclic AMP in oocytes controls meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary, Wang, Y., Teng, Z., Li, G., Mu, X., Wang, Z., Feng, L., Niu, W., Huang, K., Xiang, X., Wang, C., Zhang, H., & Xia, G., 2015
S100A8, an oocyte-specific chemokine, directs the migration of ovarian somatic cells during mouse primordial follicle assembly, Teng, Z., Wang, C., Wang, Y., Huang, K., Xiang, X., Niu, W., Feng, L., Zhao, L., Yan, H., Zhang, H., & Xia, G., 2015
Transforming growth factor-β signaling participates in the maintenance of the primordial follicle pool in the mouse ovary, Wang, Z.-P., Mu, X.-Y., Guo, M., Wang, Y.-J., Teng, Z., Mao, G.-P., Niu, W.-B., Feng, L.-Z., Zhao, L.-H., & Xia, G.-L., 2014
Effect of different culture systems and 3, 5, 3'-triiodothyronine/follicle-stimulating hormone on preantral follicle development in mice, Zhang, C., Wang, X., Wang, Z., Niu, W., Zhu, B., & Xia, G., 2013
The effect of gonadotropin on glucose transport and apoptosis in rat ovary, Zhang, C., Niu, W., Wang, Z., Wang, X., & Xia, G., 2012

Primordial Follicles Mammalian Germline Cysts Balbiani Body Cell Differentiation Molecular Mechanisms Ovarian Diseases Reproductive Resources Cellular Organelles Rna Molecules

Ning-Fang Ma - Guangzhou Medical University

Xiaozhong Peng - Peking Union Medical College

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