Professor | Jing Yang | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Jing Yang
Contact Information	yangjingliu2013@163.com
Language ability	Chinese, English
Province	Hubei

Upload Avatar (500 x 500)

Name

Jing Yang

Contact Information

yangjingliu2013@163.com

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1998-2001: PhD in Internal Medicine, Wuhan University 1987-1990: Master in Pathogenic Biology, Hubei Medical University 1982-1987: Bachelor in Clinical Medicine, Hubei Medical University
Work Experience	2007-present: Professor, Deputy Head of Department, Pharmacology Department, School of Basic Medical Sciences, Wuhan University 2002-2006: Associate Professor, Deputy Head of Department, Pharmacology Department, Medical School, Wuhan University 2006: Research Fellow, Department of Pharmacology, Fukushima Medical University, Japan 1990-1998: Physician, Senior Physician, Clinical Pharmacology Laboratory, Hubei Institute of Geriatrics
Awards	2011: New Drug Certificate and Production License for Valtrate Extract and Spasmolysis Capsule (Drug Approval Number: Z20110032; Drug Registration Number: 2011S00735) 2006: Third Prize, Wuhan Science and Technology Progress Award for the clinical and experimental study of Pinglv Compound in treating arrhythmia

University/Lab Affiliation and Title

Wuhan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1998-2001: PhD in Internal Medicine, Wuhan University
1987-1990: Master in Pathogenic Biology, Hubei Medical University
1982-1987: Bachelor in Clinical Medicine, Hubei Medical University

Work Experience

2007-present: Professor, Deputy Head of Department, Pharmacology Department, School of Basic Medical Sciences, Wuhan University
2002-2006: Associate Professor, Deputy Head of Department, Pharmacology Department, Medical School, Wuhan University
2006: Research Fellow, Department of Pharmacology, Fukushima Medical University, Japan
1990-1998: Physician, Senior Physician, Clinical Pharmacology Laboratory, Hubei Institute of Geriatrics

Awards

2011: New Drug Certificate and Production License for Valtrate Extract and Spasmolysis Capsule (Drug Approval Number: Z20110032; Drug Registration Number: 2011S00735)
2006: Third Prize, Wuhan Science and Technology Progress Award for the clinical and experimental study of Pinglv Compound in treating arrhythmia

Areas of Focus	Functional studies of important lipid metabolites in cell membranes Innovative drug research and development
Publications	CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis, Yang J et al., 2017 Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma, Yang J et al., 2017 20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo, Yang J et al., 2014 Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6, Yang J et al., 2014 Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion, Yang J et al., 2014 Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer, Yang J et al., 2013 Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer, Yang J et al., 2012 Antitumor and immunostimulatory activity of a polysaccharide–protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice, Yang J et al., 2012 Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer, Yang J et al., 2011 Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats, Yang J et al., 2006

Areas of Focus

Functional studies of important lipid metabolites in cell membranes
Innovative drug research and development

Publications

CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis, Yang J et al., 2017
Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma, Yang J et al., 2017
20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo, Yang J et al., 2014
Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6, Yang J et al., 2014
Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion, Yang J et al., 2014
Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer, Yang J et al., 2013
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer, Yang J et al., 2012
Antitumor and immunostimulatory activity of a polysaccharide–protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice, Yang J et al., 2012
Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer, Yang J et al., 2011
Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats, Yang J et al., 2006

Lipid Metabolism Cell Membrane Tumor Angiogenesis Metastasis Arachidonic Acid Cox Lox Cyp Enzymes Biological Activity Disease Processes Drug Targets Traditional Chinese Medicine Structural Modification Pharmacodynamics Toxicology Multi-Target Drugs Synergistic Effects Side Effects Drug Development Clinical Trials

Xie Xianfei - Wuhan University

Bing Jia - Peking University

Sui Meihua - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us