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Fen Du
Basic Medical Sciences
Wuhan University
Hubei
Language: Chinese, English
Atherosclerosis
Molecular Mechanisms
Therapeutic Targets
Vascular Wall Cells
Protein Structure
Methionine Sulfoxide Reductase A
Microrna
Small Molecule Peptides
Intervention Mechanisms
Potential Therapeutic Value
Areas of Focus
- Molecular mechanisms and therapeutic targets in atherosclerosis
Work Experience
- 2009-present: Associate Professor, Department of Biochemistry and Molecular Biology, Wuhan University
- 2010-2012: Postdoctoral Fellow, Medical School, University of South Carolina, USA
- 2006-2009: Lecturer, Department of Biochemistry and Molecular Biology, Wuhan University
Academic Background & Achievements
- 2001-2006: PhD in Structural Biology, Wuhan University
- 1995-2000: Bachelor of Medicine, Tongji Medical College (now Tongji Medical College of Huazhong University of Science and Technology)
Publications
- Scavenger receptor BI and atherosclerosis, Du Fen, Yu Hong*, 2018
- Isoliquiritigenin Attenuates Atherogenesis in Apolipoprotein E-Deficient Mice, Du Fen, Gesang QZ, Cao J, Qian M, Ma L, Wu DF, Yu H*, 2016
- A human apolipoprotein e mimetic peptide reduces atherosclerosis in aged apolipoprotein e null mice, Xu YY, Liu HM, Liu MT, Li FF, Liu LC, Du Fen, Fan D, Yu H*, 2016
- PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice, Wu Y, Xie G, Xu Y, Ma L, Tong C, Fan D, Du Fen*, Yu H*, 2015
- Hepatic overexpression of methionine sulfoxide reductase A reduces atherosclerosis in apolipoprotein E-deficient mice, Xu YY, Du Fen, Meng B, Xie GH, Cao J, Fan D, Yu H*, 2015
- Effect of The Apolipoprotein E Mimetic Peptide EpK on Atherosclerosis in apoE-/- Mice, Cao J, Xu YY, Shang L, Liu HM, Du Fen, Yu H*, 2015
- MicroRNA-155 Deficiency Results in Deceased Macrophage Inflammation and Attenuated Atherogenesis in Apolipoprotein E-Deficient Mice, Du Fen, Yu F, Wang Y, Hui Y, Carnevale K, Fu M, Lu H, Fan D, 2014
- Bone Marrow Deficiency of MCPIP1 Results in Severe Multi-Organ Inflammation but Diminishes Atherogenesis in Hyperlipidemic Mice, Yu F, Du Fen, Wang Y, Huang S, Miao R, Major AS, Murphy EA, Fu M, Fan D*, 2013
- Novel Domain Interaction Regulates Secretion of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Protein, Du Fen, Hui Y, Zhang M, Linton MF, Fazio S, Fan D*, 2011
- HNP-1 involved in different oxidation mechanisms in human endothelial cells, Du Fen, Ping L, He C, Yu H, Cao J, Wu J*, 2011
Awards
- 2016: Third Prize, 16th Hubei Province Natural Science Excellent Academic Paper
- 2010: Second Prize, Hubei Province Natural Science Award for research on protein folding mechanisms
