Professor | Minghua Deng | Asia Growth Partners

Name	Minghua Deng
Contact Information	{'en': 'dengmh at math dot pku dot edu dot cn', 'zh': 'dengmh at math dot pku dot edu dot cn', 'de': 'dengmh at math dot pku dot edu dot cn'}
Language ability	Chinese, English
Province	Beijing

Name

Minghua Deng

Contact Information

{'en': 'dengmh at math dot pku dot edu dot cn', 'zh': 'dengmh at math dot pku dot edu dot cn', 'de': 'dengmh at math dot pku dot edu dot cn'}

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Mathematical Sciences
Academic Background & Achievements	Postdoctoral Researcher at University of Southern California, Department of Biological Sciences, Molecular and Computational Biology (2001-2003)
Work Experience	2009.8-present - Peking University, School of Mathematical Sciences - Professor 2003.8-2009.7 - Peking University, School of Mathematical Sciences - Associate Professor 2009.8-2010.1 - Yale University School of Medicine, Division of Biostatistics - Visiting Assistant Professor 2001.2-2003.8 - University of Southern California, Department of Biological Sciences, Molecular and Computational Biology - Postdoctoral Researcher
Awards	1999 - Excellent Mainstream Basic Course and Teaching Excellence Award (Advanced Mathematics B, Zheng Zhiming)

University/Lab Affiliation and Title

Peking University

Faculty

Mathematical Sciences

Academic Background & Achievements

Postdoctoral Researcher at University of Southern California, Department of Biological Sciences, Molecular and Computational Biology (2001-2003)

Work Experience

2009.8-present - Peking University, School of Mathematical Sciences - Professor
2003.8-2009.7 - Peking University, School of Mathematical Sciences - Associate Professor
2009.8-2010.1 - Yale University School of Medicine, Division of Biostatistics - Visiting Assistant Professor
2001.2-2003.8 - University of Southern California, Department of Biological Sciences, Molecular and Computational Biology - Postdoctoral Researcher

Awards

1999 - Excellent Mainstream Basic Course and Teaching Excellence Award (Advanced Mathematics B, Zheng Zhiming)

Areas of Focus	Computational Biology Biostatistics Protein-Protein Interactions Gene Function Prediction Biomedical Informatics
Publications	Representation tensor product and quantum symmetry, Qunfeng Yang, Minghua Deng, 1995 Segmentation of Connected Image Based on Phase-locking, Minghua Deng, Minping Qian, 1996 The Exploratory Statistics and Neural Networks, M.P. Qian, M. Deng, 1998 Handwritten Chinese Character Recognition Method Based on Hidden Markov Model (HMM) and Its Implementation, Minghua Deng, Minping Qian, 1997 Application of Data Fusion in Handwritten Chinese Character Recognition, Xueqing Zhu, Minping Qian, Minghua Deng, 1998 A Novel Algorithm for Handwritten Chinese Character Recognition, Feng Qi, Minghua Deng, Minping Qian, Xueqing Zhu, 2000 Inferring domain-domain interactions from protein-protein interactions, M. Deng, S. Mehta, F. Sun, T. Chen, 2002 A dynamic programming approach for haplotype partitioning, K. Zhang, M. Deng, T. Chen, M.S. Waterman, F. Sun, 2002 Assessment of the reliability of protein-protein interactions and protein function prediction, M. Deng, F. Sun, T. Chen, 2003 Prediction of protein function using protein-protein interaction data, M. Deng, K. Zhang, S. Mehta, T. Chen, F. Sun, 2003 Kernel-based data fusion and its application to protein function prediction in yeast, G.R.G. Lanckriet, M. Deng, N. Cristianini, M.I. Jordan, W.S. Noble, 2004 Mapping Gene Ontology to proteins based on protein-protein interaction data, M. Deng, Z. Tu, T. Chen, F. Sun, 2004 An integrative analysis of protein function prediction, M. Deng, T. Chen, F. Sun, 2004 Application of hidden semi-Markov model to 3-prime splice sites identification, Xiucheng Feng, Minping Qian, Minghua Deng, Ma Xiaotu, Yan Xiting, 2004 Detecting differentially expressed genes by relative entropy, Xiting Yan, Minghua Deng, Wing K. Fung, Minping Qian, 2005 Biomedical information processing - DNA microarray data application in medicine, Jinwen Ma, Minghua Deng, 2005 Understanding protein-protein interactions: from domain level to motif level, Huan Yu, Minping Qian, Minghua Deng, 2005 An efficient algorithm for deciphering regulatory motifs, Xiucheng Feng, Lin Wan, Minghua Deng, Fengzhu Sun, Minping Qian, 2005 ClustalY: Speed up the guide tree building for ClustalW, Huan Yu, Minghua Deng, 2005 Diffusion kernel based logistic regression models for protein function prediction, H. Lee, Z. Tu, M. Deng, F. Sun, T. Chen, 2006 Inferring domain-domain interactions from multiple biological data sources, H. Lee, M. Deng, F. Sun, T. Chen, 2006 Stochastic model of yeast cell-cycle network, Yuping Zhang, Minping Qian, Qi Ouyang, Minghua Deng, Fangting Li, Chao Tang, 2006 Using a stochastic Adaboost algorithm to discover interactome motif pairs from sequence, Huan Yu, Minping Qian, Minghua Deng, 2006 Nonequilibrium Model for Yeast Cell Cycle, Yuping Zhang, Huan Yu, Minghua Deng, Minping Qian, 2006 k-gram method for identifying MicroRNA precursors, Lianghuai Yang, Piming Lü, Lijun Chen, Minghua Deng, 2007 Comparison of chip data normalization methods, Xiaojun Tan, Yongxin Zhang, Minping Qian, Youyi Zhang, Minghua Deng, 2007 A critical assessment of Mus musculus gene function prediction using integrated genomic evidence, Lourdes Pena-Castillo, Murat Tasan, Chad L Myers, Hyunju Lee, Trupti Joshi, Chao Zhang, Yuanfang Guan, Michele Leone, Andrea Pagnani, Wan Kyu Kim, Chase Krumpelman, Weidong Tian, Guillaume Obozinski, Yanjun Qi, Sara Mostafavi, Guan Ning Lin, Gabriel F Berriz, Francis D Gibbons, Gert Lanckriet, Jian Qiu, Charles Grant, Zafer Barutcuoglu, David P Hill, David Warde-Farley, Chris Grouios, Debajyoti Ray, Judith A Blake, Minghua Deng, Michael I Jordan, William S Noble, Quaid Morris, Judith Klein-Seetharaman, Ziv Bar-Joseph, Ting Chen, Fengzhu Sun, Olga G Troyanskaya, Edward M Marcotte, Dong Xu, Timothy R Hughes, Frederick P Roth, 2008 A Method to Correct Systematic Bias in Affymetrix SNP Arrays, Lin Wan, Wenjiang J. Fu, Minghua Deng, Minping Qian, 2008 On Design of Oligonucleotide SNP Arrays and Methods for Genotype Calling, Wenjiang J. Fu, Ming Li, Lin Wan, Minghua Deng, Minping Qian, 2008 A robust empirical Bayesian method for detecting differentially expressed genes, Fugui Wang, Lin Hou, Jiangfeng Xu, Minping Qian, Minghua Deng, 2009 The Implementation and Application of the Microarray Preprocessing Generalized PDNN Model, Wei Wei, Lin Wan, Minping Qian, Minghua Deng, 2009 Conservation and Implications of Eukaryote Transcriptional Regulatory Regions across Multiple Species, Lin Wan, Dayong Li, Donglei Zhang, Xue Liu, Wenjiang J. Fu, Lihuang Zhu, Minghua Deng, Fengzhu Sun, Minping Qian, 2008 REMAS: a new regression model to identify alternative splicing events from exon array data, Hao Zheng, Xingyi Hang, Ji Zhu, Minping Qian, Wubin Qu, Chenggang Zhang, Minghua Deng, 2009 Searching for bidirectional promoters in Arabidopsis thaliana, Quan Wang, Lin Wan, Dayong Li, Lihuang Zhu, Minping Qian, Minghua Deng, 2009 Nonlinear cooperation of p53-ING1-induced bax expression and protein S-nitrosylation in GSNO-induced thymocyte apoptosis: A quantitative approach with cross-platform validation, Shaojin Duan, Lin Wan, Wenjiang J. Fu, Hong Pan, Qi Ding, Chang Chen, Peiwei Han, Xiaoyan Zhu, Liying Du, Hongxiao Liu, Yuxia Chen, Ximing Liu, Xiting Yan, Minghua Deng, Minping Qian, 2009 Using PLS-VIP method to screen differentially expressed genes, Fang Han, Jingchen Wu, Jiangfeng Xu, Minghua Deng, 2009 Progress in bioinformatics research on transcription factor binding sites, Lin Hou, Minping Qian, Yunping Zhu, Minghua Deng, 2009 Pathway Detection Based on Hierarchical LASSO Regression Model, Hao Zheng, Fugui Wang, Jiangfeng Xu, Nengfeng Zhou, Minping Qian, Ji Zhu, Minghua Deng, 2009 Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array, X. Hang, P. Li, Z. Li, W. Qu, Y. Yu, H. Li, Z. Shen, H. Zheng, Y. Gao, Y. Wu, M. Deng, Z. Sun, C. Zhang, 2009

Areas of Focus

Computational Biology
Biostatistics
Protein-Protein Interactions
Gene Function Prediction
Biomedical Informatics

Publications

Representation tensor product and quantum symmetry, Qunfeng Yang, Minghua Deng, 1995
Segmentation of Connected Image Based on Phase-locking, Minghua Deng, Minping Qian, 1996
The Exploratory Statistics and Neural Networks, M.P. Qian, M. Deng, 1998
Handwritten Chinese Character Recognition Method Based on Hidden Markov Model (HMM) and Its Implementation, Minghua Deng, Minping Qian, 1997
Application of Data Fusion in Handwritten Chinese Character Recognition, Xueqing Zhu, Minping Qian, Minghua Deng, 1998
A Novel Algorithm for Handwritten Chinese Character Recognition, Feng Qi, Minghua Deng, Minping Qian, Xueqing Zhu, 2000
Inferring domain-domain interactions from protein-protein interactions, M. Deng, S. Mehta, F. Sun, T. Chen, 2002
A dynamic programming approach for haplotype partitioning, K. Zhang, M. Deng, T. Chen, M.S. Waterman, F. Sun, 2002
Assessment of the reliability of protein-protein interactions and protein function prediction, M. Deng, F. Sun, T. Chen, 2003
Prediction of protein function using protein-protein interaction data, M. Deng, K. Zhang, S. Mehta, T. Chen, F. Sun, 2003
Kernel-based data fusion and its application to protein function prediction in yeast, G.R.G. Lanckriet, M. Deng, N. Cristianini, M.I. Jordan, W.S. Noble, 2004
Mapping Gene Ontology to proteins based on protein-protein interaction data, M. Deng, Z. Tu, T. Chen, F. Sun, 2004
An integrative analysis of protein function prediction, M. Deng, T. Chen, F. Sun, 2004
Application of hidden semi-Markov model to 3-prime splice sites identification, Xiucheng Feng, Minping Qian, Minghua Deng, Ma Xiaotu, Yan Xiting, 2004
Detecting differentially expressed genes by relative entropy, Xiting Yan, Minghua Deng, Wing K. Fung, Minping Qian, 2005
Biomedical information processing - DNA microarray data application in medicine, Jinwen Ma, Minghua Deng, 2005
Understanding protein-protein interactions: from domain level to motif level, Huan Yu, Minping Qian, Minghua Deng, 2005
An efficient algorithm for deciphering regulatory motifs, Xiucheng Feng, Lin Wan, Minghua Deng, Fengzhu Sun, Minping Qian, 2005
ClustalY: Speed up the guide tree building for ClustalW, Huan Yu, Minghua Deng, 2005
Diffusion kernel based logistic regression models for protein function prediction, H. Lee, Z. Tu, M. Deng, F. Sun, T. Chen, 2006
Inferring domain-domain interactions from multiple biological data sources, H. Lee, M. Deng, F. Sun, T. Chen, 2006
Stochastic model of yeast cell-cycle network, Yuping Zhang, Minping Qian, Qi Ouyang, Minghua Deng, Fangting Li, Chao Tang, 2006
Using a stochastic Adaboost algorithm to discover interactome motif pairs from sequence, Huan Yu, Minping Qian, Minghua Deng, 2006
Nonequilibrium Model for Yeast Cell Cycle, Yuping Zhang, Huan Yu, Minghua Deng, Minping Qian, 2006
k-gram method for identifying MicroRNA precursors, Lianghuai Yang, Piming Lü, Lijun Chen, Minghua Deng, 2007
Comparison of chip data normalization methods, Xiaojun Tan, Yongxin Zhang, Minping Qian, Youyi Zhang, Minghua Deng, 2007
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence, Lourdes Pena-Castillo, Murat Tasan, Chad L Myers, Hyunju Lee, Trupti Joshi, Chao Zhang, Yuanfang Guan, Michele Leone, Andrea Pagnani, Wan Kyu Kim, Chase Krumpelman, Weidong Tian, Guillaume Obozinski, Yanjun Qi, Sara Mostafavi, Guan Ning Lin, Gabriel F Berriz, Francis D Gibbons, Gert Lanckriet, Jian Qiu, Charles Grant, Zafer Barutcuoglu, David P Hill, David Warde-Farley, Chris Grouios, Debajyoti Ray, Judith A Blake, Minghua Deng, Michael I Jordan, William S Noble, Quaid Morris, Judith Klein-Seetharaman, Ziv Bar-Joseph, Ting Chen, Fengzhu Sun, Olga G Troyanskaya, Edward M Marcotte, Dong Xu, Timothy R Hughes, Frederick P Roth, 2008
A Method to Correct Systematic Bias in Affymetrix SNP Arrays, Lin Wan, Wenjiang J. Fu, Minghua Deng, Minping Qian, 2008
On Design of Oligonucleotide SNP Arrays and Methods for Genotype Calling, Wenjiang J. Fu, Ming Li, Lin Wan, Minghua Deng, Minping Qian, 2008
A robust empirical Bayesian method for detecting differentially expressed genes, Fugui Wang, Lin Hou, Jiangfeng Xu, Minping Qian, Minghua Deng, 2009
The Implementation and Application of the Microarray Preprocessing Generalized PDNN Model, Wei Wei, Lin Wan, Minping Qian, Minghua Deng, 2009
Conservation and Implications of Eukaryote Transcriptional Regulatory Regions across Multiple Species, Lin Wan, Dayong Li, Donglei Zhang, Xue Liu, Wenjiang J. Fu, Lihuang Zhu, Minghua Deng, Fengzhu Sun, Minping Qian, 2008
REMAS: a new regression model to identify alternative splicing events from exon array data, Hao Zheng, Xingyi Hang, Ji Zhu, Minping Qian, Wubin Qu, Chenggang Zhang, Minghua Deng, 2009
Searching for bidirectional promoters in Arabidopsis thaliana, Quan Wang, Lin Wan, Dayong Li, Lihuang Zhu, Minping Qian, Minghua Deng, 2009
Nonlinear cooperation of p53-ING1-induced bax expression and protein S-nitrosylation in GSNO-induced thymocyte apoptosis: A quantitative approach with cross-platform validation, Shaojin Duan, Lin Wan, Wenjiang J. Fu, Hong Pan, Qi Ding, Chang Chen, Peiwei Han, Xiaoyan Zhu, Liying Du, Hongxiao Liu, Yuxia Chen, Ximing Liu, Xiting Yan, Minghua Deng, Minping Qian, 2009
Using PLS-VIP method to screen differentially expressed genes, Fang Han, Jingchen Wu, Jiangfeng Xu, Minghua Deng, 2009
Progress in bioinformatics research on transcription factor binding sites, Lin Hou, Minping Qian, Yunping Zhu, Minghua Deng, 2009
Pathway Detection Based on Hierarchical LASSO Regression Model, Hao Zheng, Fugui Wang, Jiangfeng Xu, Nengfeng Zhou, Minping Qian, Ji Zhu, Minghua Deng, 2009
Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array, X. Hang, P. Li, Z. Li, W. Qu, Y. Yu, H. Li, Z. Shen, H. Zheng, Y. Gao, Y. Wu, M. Deng, Z. Sun, C. Zhang, 2009

Computational Biology Biostatistics Protein Interactions Gene Prediction Biomedical Informatics Data Analysis Molecular Biology Genomics Bioinformatics Statistical Methods

Zou Xiufen - Wuhan University

Lin Wei - Peking University

Liu Yanyan - Wuhan University

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