Professor | Guohua Yang | Asia Growth Partners

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Name	Guohua Yang
Contact Information	ghyang@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Guohua Yang

Contact Information

ghyang@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1992-1995: Associate Degree in Biology from Hubei Engineering College (formerly Xiaogan Teachers College) 2001-2006: Master and PhD in Genetics from Wuhan University
Work Experience	2011-present: Associate Professor at Wuhan University School of Basic Medical Sciences 2014-2015: Visiting Scholar at Cleveland Medical Center, USA 2006-2010: Lecturer at Wuhan University School of Basic Medical Sciences 2010-2011: Deputy Director at Suizhou City Health Bureau, Hubei Province 1995-1999: Biology Teacher at Wuhan Iron and Steel Ninth Middle School
Awards	2006: Outstanding Young (Student) at Wuhan University 2009: Excellent Guide Teacher for Wuhan University Students' Summer Social Practice 2014: Second Prize at the 'Chunhui Cup' Chinese Overseas Innovation and Entrepreneurship Competition, New York Area 2017: Most Potential Award at the 'Huachuang Cup' Innovation and Entrepreneurship Competition, Biomedical Field 2019: Outstanding Party Worker at Wuhan University School of Basic Medical Sciences 2021: Outstanding Class Tutor at Wuhan University School of Basic Medical Sciences 2021: Wuhan University Teaching Achievement Award (Professional Theory Class Category) 2021 and 2022: First Prize at Wuhan University in the 'Internet+' College Students Innovation and Entrepreneurship Competition, Silver Prize in Hubei Province 2023: 'Gold Award' at Wuhan University Staff Innovation and Entrepreneurship Competition 2023: 'Top Ten Entrepreneurs of Hubei Province' at the Sixth Hubei Provincial Education, Science, Culture, Health, and Sports System Staff Entrepreneurship and Innovation Finals

University/Lab Affiliation and Title

Wuhan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1992-1995: Associate Degree in Biology from Hubei Engineering College (formerly Xiaogan Teachers College)
2001-2006: Master and PhD in Genetics from Wuhan University

Work Experience

2011-present: Associate Professor at Wuhan University School of Basic Medical Sciences
2014-2015: Visiting Scholar at Cleveland Medical Center, USA
2006-2010: Lecturer at Wuhan University School of Basic Medical Sciences
2010-2011: Deputy Director at Suizhou City Health Bureau, Hubei Province
1995-1999: Biology Teacher at Wuhan Iron and Steel Ninth Middle School

Awards

2006: Outstanding Young (Student) at Wuhan University
2009: Excellent Guide Teacher for Wuhan University Students' Summer Social Practice
2014: Second Prize at the 'Chunhui Cup' Chinese Overseas Innovation and Entrepreneurship Competition, New York Area
2017: Most Potential Award at the 'Huachuang Cup' Innovation and Entrepreneurship Competition, Biomedical Field
2019: Outstanding Party Worker at Wuhan University School of Basic Medical Sciences
2021: Outstanding Class Tutor at Wuhan University School of Basic Medical Sciences
2021: Wuhan University Teaching Achievement Award (Professional Theory Class Category)
2021 and 2022: First Prize at Wuhan University in the 'Internet+' College Students Innovation and Entrepreneurship Competition, Silver Prize in Hubei Province
2023: 'Gold Award' at Wuhan University Staff Innovation and Entrepreneurship Competition
2023: 'Top Ten Entrepreneurs of Hubei Province' at the Sixth Hubei Provincial Education, Science, Culture, Health, and Sports System Staff Entrepreneurship and Innovation Finals

Areas of Focus	Functional research on genetic mutations in genetic diseases Research on new methods of genetic diagnosis Molecular mechanisms and drug discovery in liver cancer
Publications	Truncated FRMD7 Proteins in Congenital Nystagmus: Novel Frameshift Mutations and Proteasomal Pathway Implications, Guohua Yang et al., 2024 Autophagy inhibition mediated by trillin promotes apoptosis in hepatocellular carcinoma cells via activation of mTOR/STAT3 signaling, Guohua Yang et al., 2023 Double-network cellulose-based hybrid hydrogels with favourable biocompatibility and antibacterial activity for wound healing, Guohua Yang et al., 2023 Machine learning-based transcriptome analysis of lipid metabolism biomarkers for the survival prediction in hepatocellular carcinoma, Guohua Yang et al., 2022 DJ-1/FGFR-1 Signaling Pathway Contributes to Sorafenib Resistance in Hepatocellular Carcinoma, Guohua Yang et al., 2022 C1R, CL2, and TNFRSF1A Genes in Coronavirus Disease-COVID-19 Pathway Serve as Novel Molecular Biomarkers of GBM Prognosis and Immune Infiltration, Guohua Yang et al., 2022 Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway, Guohua Yang et al., 2021 Dissecting Tumor Antigens and Immune Subtypes of Glioma to Develop mRNA Vaccine, Guohua Yang et al., 2021 A novel TSC1 frameshift mutation c.1550_1551del causes tuberous sclerosis complex by aberrant splicing and nonsense-mediated mRNA degradation (NMD) simultaneously in a Chinese family, Guohua Yang et al., 2020 Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells, Guohua Yang et al., 2020 Identification and Interaction Analysis of Significant Genes and MicroRNAs in Pterygium, Guohua Yang et al., 2019

Areas of Focus

Functional research on genetic mutations in genetic diseases
Research on new methods of genetic diagnosis
Molecular mechanisms and drug discovery in liver cancer

Publications

Truncated FRMD7 Proteins in Congenital Nystagmus: Novel Frameshift Mutations and Proteasomal Pathway Implications, Guohua Yang et al., 2024
Autophagy inhibition mediated by trillin promotes apoptosis in hepatocellular carcinoma cells via activation of mTOR/STAT3 signaling, Guohua Yang et al., 2023
Double-network cellulose-based hybrid hydrogels with favourable biocompatibility and antibacterial activity for wound healing, Guohua Yang et al., 2023
Machine learning-based transcriptome analysis of lipid metabolism biomarkers for the survival prediction in hepatocellular carcinoma, Guohua Yang et al., 2022
DJ-1/FGFR-1 Signaling Pathway Contributes to Sorafenib Resistance in Hepatocellular Carcinoma, Guohua Yang et al., 2022
C1R, CL2, and TNFRSF1A Genes in Coronavirus Disease-COVID-19 Pathway Serve as Novel Molecular Biomarkers of GBM Prognosis and Immune Infiltration, Guohua Yang et al., 2022
Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway, Guohua Yang et al., 2021
Dissecting Tumor Antigens and Immune Subtypes of Glioma to Develop mRNA Vaccine, Guohua Yang et al., 2021
A novel TSC1 frameshift mutation c.1550_1551del causes tuberous sclerosis complex by aberrant splicing and nonsense-mediated mRNA degradation (NMD) simultaneously in a Chinese family, Guohua Yang et al., 2020
Trillin prevents proliferation and induces apoptosis through inhibiting STAT3 nuclear translocation in hepatoma carcinoma cells, Guohua Yang et al., 2020
Identification and Interaction Analysis of Significant Genes and MicroRNAs in Pterygium, Guohua Yang et al., 2019

Genetic Diseases Gene Mutations Functional Research Genetic Diagnosis New Methods Liver Cancer Molecular Mechanisms Drug Discovery Biomedical Research Clinical Applications

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