Professor | Bo Bai | Asia Growth Partners

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Name	Bo Bai
Contact Information	baib@mail.sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Bo Bai

Contact Information

baib@mail.sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	2005-2009 Bachelor and Master in Cardiovascular Pharmacology, Sichuan University, West China School of Pharmacy 2009-2014 PhD in Cardiovascular Biomedicine, The University of Hong Kong, Li Ka Shing Faculty of Medicine 2014-2019 Postdoctoral Fellow in Cardiovascular Biomedicine, A*STAR, Singapore
Work Experience	2022/07-Present, Southern University of Science and Technology, School of Public Health and Emergency Management, Research Assistant Professor 2019/06-2022/06, Shenzhen Second People's Hospital, Department of Cardiology, Full-time Researcher 2016/09-2020/08, The University of Hong Kong, Li Ka Shing Faculty of Medicine, Honorary Assistant Professor (part-time) 2005/08-2009/08, Beijing China-Japan Friendship Hospital, Department of Pharmacy, Clinical Pharmacist

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

2005-2009 Bachelor and Master in Cardiovascular Pharmacology, Sichuan University, West China School of Pharmacy
2009-2014 PhD in Cardiovascular Biomedicine, The University of Hong Kong, Li Ka Shing Faculty of Medicine
2014-2019 Postdoctoral Fellow in Cardiovascular Biomedicine, A*STAR, Singapore

Work Experience

2022/07-Present, Southern University of Science and Technology, School of Public Health and Emergency Management, Research Assistant Professor
2019/06-2022/06, Shenzhen Second People's Hospital, Department of Cardiology, Full-time Researcher
2016/09-2020/08, The University of Hong Kong, Li Ka Shing Faculty of Medicine, Honorary Assistant Professor (part-time)
2005/08-2009/08, Beijing China-Japan Friendship Hospital, Department of Pharmacy, Clinical Pharmacist

Areas of Focus	Molecular pathophysiological mechanisms of coronary heart disease caused by endothelial aging based on population cohort data, model animals, and multi-omics studies Pathogenesis of heart failure from the interaction between the immune system and cardiovascular system, searching for new drug intervention targets
Publications	Pathogenic roles of neutrophil-derived alarmins (S100A8/A9) in heart failure: from molecular mechanisms to therapeutic insights, Bo BAI, Yun Xu, Haibo Chen, 2022 High neutrophil to lymphocyte ratio and its gene signatures correlate with diastolic dysfunction in heart failure with preserved ejection fraction, Bo BAI, Min Cheng, Lingyan Jiang, et al., 2021 Metformin: A novel weapon against inflammation, Bo BAI, Haibo Chen, 2021 The pregnancy-associated spontaneous coronary artery dissection in a young woman with a novel missense mutation in NOTCH1: a case report, Bo BAI, Meng Zhang, Yihao Zhuang, et al., 2020 Seipin knockout mice develop heart failure with preserved ejection fraction, Bo BAI, Wulin Yang, Yanyun Fu, et al., 2019 CDK5, YM Guo, Yu Wang, Bo BAI, 2018 Cloning and characterization of sirtuin3 (SIRT3), AW Man, Bo BAI, Yu Wang, 2016 Loss of SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5, Bo BAI, Vanhoutte PM, Yu Wang, 2014 Methods to investigate the role of SIRT1 in endothelial senescence, Bo BAI, Yu Wang, 2012 Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis, Bo BAI, Yan Liang, Cheng Xu, et al., 2012 The use of lorcaserin in the management of obesity: a critical appraisal, Bo BAI, Yu Wang, 2011

Areas of Focus

Molecular pathophysiological mechanisms of coronary heart disease caused by endothelial aging based on population cohort data, model animals, and multi-omics studies
Pathogenesis of heart failure from the interaction between the immune system and cardiovascular system, searching for new drug intervention targets

Publications

Pathogenic roles of neutrophil-derived alarmins (S100A8/A9) in heart failure: from molecular mechanisms to therapeutic insights, Bo BAI, Yun Xu, Haibo Chen, 2022
High neutrophil to lymphocyte ratio and its gene signatures correlate with diastolic dysfunction in heart failure with preserved ejection fraction, Bo BAI, Min Cheng, Lingyan Jiang, et al., 2021
Metformin: A novel weapon against inflammation, Bo BAI, Haibo Chen, 2021
The pregnancy-associated spontaneous coronary artery dissection in a young woman with a novel missense mutation in NOTCH1: a case report, Bo BAI, Meng Zhang, Yihao Zhuang, et al., 2020
Seipin knockout mice develop heart failure with preserved ejection fraction, Bo BAI, Wulin Yang, Yanyun Fu, et al., 2019
CDK5, YM Guo, Yu Wang, Bo BAI, 2018
Cloning and characterization of sirtuin3 (SIRT3), AW Man, Bo BAI, Yu Wang, 2016
Loss of SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5, Bo BAI, Vanhoutte PM, Yu Wang, 2014
Methods to investigate the role of SIRT1 in endothelial senescence, Bo BAI, Yu Wang, 2012
Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis, Bo BAI, Yan Liang, Cheng Xu, et al., 2012
The use of lorcaserin in the management of obesity: a critical appraisal, Bo BAI, Yu Wang, 2011

Endothelial Aging Coronary Heart Disease Molecular Mechanisms Population Cohort Model Animals Multi-Omics Heart Failure Immune System Cardiovascular System Drug Targets

Wei Zhang - Wuhan University

Ming Chen - Wuhan University

Jinping Lu - Wuhan University

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