Professor | Jianyang Hu | Asia Growth Partners

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Name	Jianyang Hu
Contact Information	hujy@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Jianyang Hu

Contact Information

hujy@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	2017.09-2020.10 PhD, Biomedical Sciences, City University of Hong Kong 2012.09-2015.06 Master's, Pharmacology, Jinan University 2008.09-2012.06 Bachelor's, Pharmacy, Guangzhou University of Chinese Medicine
Work Experience	2023.08-present Assistant Research Professor, Southern University of Science and Technology, School of Medicine 2021.07-2023.07 Postdoctoral Researcher, Southern University of Science and Technology, School of Medicine 2020.10-2021.06 Postdoctoral Researcher, City University of Hong Kong, Department of Biomedical Sciences 2017.02-2017.08 Research Assistant, City University of Hong Kong, Department of Biomedical Sciences
Awards	National Natural Science Foundation of China (Youth Project) Shenzhen Science and Innovation Commission - Excellent Science and Technology Innovation Talent Training Project (Youth Project) China Postdoctoral Science Foundation Grant Guangdong Province Overseas Postdoctoral Talent Support Project

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

2017.09-2020.10 PhD, Biomedical Sciences, City University of Hong Kong
2012.09-2015.06 Master's, Pharmacology, Jinan University
2008.09-2012.06 Bachelor's, Pharmacy, Guangzhou University of Chinese Medicine

Work Experience

2023.08-present Assistant Research Professor, Southern University of Science and Technology, School of Medicine
2021.07-2023.07 Postdoctoral Researcher, Southern University of Science and Technology, School of Medicine
2020.10-2021.06 Postdoctoral Researcher, City University of Hong Kong, Department of Biomedical Sciences
2017.02-2017.08 Research Assistant, City University of Hong Kong, Department of Biomedical Sciences

Awards

National Natural Science Foundation of China (Youth Project)
Shenzhen Science and Innovation Commission - Excellent Science and Technology Innovation Talent Training Project (Youth Project)
China Postdoctoral Science Foundation Grant
Guangdong Province Overseas Postdoctoral Talent Support Project

Areas of Focus	Regulation of tumor cell senescence Mechanisms of tumor metastasis Intercellular communication in the tumor microenvironment, such as exosome-mediated communication
Publications	Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling, Huang H, Hu JY, et al., 2021 TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumor growth, and correlates with poor prognosis, Hu JY, Lai Y, et al., 2022 Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer, Sun HY, Hu JY, et al., 2021 Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo, Zhuo ZZ, Hu JY, et al., 2015 Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes, Zhou M, Li WP, Hu JY, et al., 2020 Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway, Liu JS, Huo CY, Hu JY, et al., 2019 The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells, Sun HY, Huang MH, Hu JY, et al., 2017 Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating β-catenin, Chen LP, Mai WQ, Hu JY, et al., 2017 Targeting tumor pericytes with a FAP-alpha-activated prodrug combats tumor resistance to vascular disrupting agents, Chen MF, Lei XP, Hu JY, et al., 2017 In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways, Lei XP, Chen MF, Hu JY, et al., 2016 New cycloartane triterpenoid from Cimicifuga foetida induces mitochondrial apoptosis in human breast carcinoma MCF-7 cells via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation, Sun HY, Liu BB, Hu JY, et al., 2016 Geleganidines A–C, Unusual Monoterpenoid Indole Alkaloids from Gelsemium elegans, Zhang W, Huang XJ, Hu JY, et al., 2015 Bufalin induces apoptosis of MDA-MB-231 cell through activation of JNK/p53 pathway, Hu JY, Chen MF, Lei XP, et al., 2015

Areas of Focus

Regulation of tumor cell senescence
Mechanisms of tumor metastasis
Intercellular communication in the tumor microenvironment, such as exosome-mediated communication

Publications

Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling, Huang H, Hu JY, et al., 2021
TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumor growth, and correlates with poor prognosis, Hu JY, Lai Y, et al., 2022
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer, Sun HY, Hu JY, et al., 2021
Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo, Zhuo ZZ, Hu JY, et al., 2015
Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes, Zhou M, Li WP, Hu JY, et al., 2020
Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway, Liu JS, Huo CY, Hu JY, et al., 2019
The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells, Sun HY, Huang MH, Hu JY, et al., 2017
Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating β-catenin, Chen LP, Mai WQ, Hu JY, et al., 2017
Targeting tumor pericytes with a FAP-alpha-activated prodrug combats tumor resistance to vascular disrupting agents, Chen MF, Lei XP, Hu JY, et al., 2017
In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways, Lei XP, Chen MF, Hu JY, et al., 2016
New cycloartane triterpenoid from Cimicifuga foetida induces mitochondrial apoptosis in human breast carcinoma MCF-7 cells via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation, Sun HY, Liu BB, Hu JY, et al., 2016
Geleganidines A–C, Unusual Monoterpenoid Indole Alkaloids from Gelsemium elegans, Zhang W, Huang XJ, Hu JY, et al., 2015
Bufalin induces apoptosis of MDA-MB-231 cell through activation of JNK/p53 pathway, Hu JY, Chen MF, Lei XP, et al., 2015

Senescence Tumor Cells Cellular Communication Exosomes Metastasis Tumor Microenvironment Cell Signaling Cancer Therapy Drug Targets Molecular Biology

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