Professor | Guoxian Pei | Asia Growth Partners

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Name	Guoxian Pei
Contact Information	peigx@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Guoxian Pei

Contact Information

peigx@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	Significant contributions in orthopedics, pioneering digital orthopedics in China. Developed new concepts and technologies for severe limb trauma treatment. First to conduct large segmental bone defect tissue engineering research internationally.
Work Experience	2019.11 to present - Southern University of Science and Technology, School of Medicine - Chair Professor 2019.11 to 2024.01 - Southern University of Science and Technology Hospital - Dean 2008.08 to 2019.10 - Fourth Military Medical University (now Air Force Medical University), Xijing Hospital of Orthopedics, National Orthopedics Institute - Dean, Director 1997.08 to 2008.07 - First Military Medical University (now Southern Medical University), Southern Hospital, Department of Trauma Orthopedics - Director 1986.06 to 1994.06 - PLA 153rd Hospital, National Microsurgery Center - Deputy Director, Director, Deputy Dean 1983.05 to 1986.05 - PLA 89th Hospital, National Trauma Surgery Center - Physician 1969.12 to 1983.04 - PLA 136th Hospital - Physician
Awards	2023: He Liang He Li Foundation Science and Technology Progress Award 2021: Fifth 'Bethune-style Good Doctor' 2020: National Science and Technology Progress Award, First Class (First Completer) 2015: Ministry of Education Natural Science Award, First Class (First Completer) 2006: Guangdong Province Science and Technology Award, First Class (First Completer) 2005: Military Science and Technology Progress Award, First Class (First Completer) 2005: Military Medical Achievement Award, First Class (First Completer) 2002: National Science and Technology Progress Award, Second Class (First Completer) 1996: National First Batch of Hundred Thousand Talents Project 1994: National Outstanding Contribution Young and Middle-aged Science and Technology Expert 1994: State Council Government Special Allowance Expert

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

Significant contributions in orthopedics, pioneering digital orthopedics in China.
Developed new concepts and technologies for severe limb trauma treatment.
First to conduct large segmental bone defect tissue engineering research internationally.

Work Experience

2019.11 to present - Southern University of Science and Technology, School of Medicine - Chair Professor
2019.11 to 2024.01 - Southern University of Science and Technology Hospital - Dean
2008.08 to 2019.10 - Fourth Military Medical University (now Air Force Medical University), Xijing Hospital of Orthopedics, National Orthopedics Institute - Dean, Director
1997.08 to 2008.07 - First Military Medical University (now Southern Medical University), Southern Hospital, Department of Trauma Orthopedics - Director
1986.06 to 1994.06 - PLA 153rd Hospital, National Microsurgery Center - Deputy Director, Director, Deputy Dean
1983.05 to 1986.05 - PLA 89th Hospital, National Trauma Surgery Center - Physician
1969.12 to 1983.04 - PLA 136th Hospital - Physician

Awards

2023: He Liang He Li Foundation Science and Technology Progress Award
2021: Fifth 'Bethune-style Good Doctor'
2020: National Science and Technology Progress Award, First Class (First Completer)
2015: Ministry of Education Natural Science Award, First Class (First Completer)
2006: Guangdong Province Science and Technology Award, First Class (First Completer)
2005: Military Science and Technology Progress Award, First Class (First Completer)
2005: Military Medical Achievement Award, First Class (First Completer)
2002: National Science and Technology Progress Award, Second Class (First Completer)
1996: National First Batch of Hundred Thousand Talents Project
1994: National Outstanding Contribution Young and Middle-aged Science and Technology Expert
1994: State Council Government Special Allowance Expert

Areas of Focus	Regenerative Orthopedic Research Intelligent and Digital Orthopedics
Publications	Microgroove Cues Guiding Fibrogenesis of Stem Cells via Intracellular Force, Lei X, Miao S, Wang X, Gao Y, Wu H, Cheng P, Song Y, Bi L, Pei G, 2023 Fractional differential equation modeling of the HBV infection with time delay and logistic proliferation, Sun D, Liu J, Su X, Pei G, 2022 Cefazolin/BMP-2-Loaded Mesoporous Silica Nanoparticles for the Repair of Open Fractures with Bone Defects, Mingkui Shen, Lulu Wang, Li Feng, Chuangye Xu, Yi Gao, Sijing Li, Yulan Wu, Guoxian Pei, 2022 Distal Humerus Morphological Analysis of Chinese Individuals: A Statistical Shape Modeling Approach, Zhao W, Guo Y, Xu C, Pei G, Basnet S, Pei Y, Su X, 2022 3D bioprinting of in situ vascularized tissue engineered bone for repairing large segmental bone defects, Mingkui Shen, Lulu Wang, Yi Gao, Li Feng, Chuangye Xu, Sijing Li, Xiaohu Wang, Yulan Wu, Yao Guo, Guoxian Pei, 2022 A 3D bioprinted nano-laponite hydrogel construct promotes osteogenesis by activating PI3K/AKT signaling pathway, Sheng Miao, Jinru Zhou, Bin Liu, Xing Lei, Taoran Wang, Xiaotian Hao, Pengzhen Cheng, Hao Wu, Yue Song, Guoxian Pei, Long Bi, 2022 bFGF-Loaded Mesoporous Silica Nanoparticles Promote Bone Regeneration Through the Wnt/β-Catenin Signalling Pathway, Mingkui Shen, Lulu Wang, Li Feng, Yi Gao, Sijing Li, Yulan Wu, Chuangye Xu, Guoxian Pei, 2022 Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion, Pengzhen Cheng, Tianqing Cao, Xueyi Zhao, Weiguang Lu, Sheng Miao, Fenru Ning, Dong Wang, Yi Gao,Long Wang, Guoxian Pei, and Liu Yang, 2022 Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro, Li JQ, Jiang HJ, Su XY, Feng L, Zhan NZ, Li SS, Chen ZJ, Chang BH, Cheng PZ, Yang L, Pei GX, 2022 Fabrication of a bio-instructive scaffold conferred with a favorable microenvironment allowing for superior implant osseointegration and accelerated in situ vascularized bone regeneration via type H vessel formation, Yijun He, Wenhao Wang, Shaozhang Lin, Yixi Yang, Lizhi Song, Yihan Jing, Lihao Chen, Zaopeng He, Wei Li, Ao Xiong, Kelvin W.K. Yeung , Qi Zhao, Yuan Jiang, Zijie Li, Guoxian Pei, Zhi-Yong Zhang, 2022 Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells, Zhang Xinxin, Jiang Xiaorui, Jiang Shan, Cai Xiyu, Yu Shengji, Pei Guoxian, 2021 Cell-loaded injectable gelatin/alginate/LAPONITE® nanocomposite hydrogel promotes bone healing in a critical-size rat calvarial defect model, Liu B, Li J, Lei X, Miao S, Zhang S, Cheng P, Song Y, Wu H, Gao Y, Bi L, Pei G, 2020 3D-bioprinted functional and biomimetic hydrogel scaffolds incorporated with nanosilicates to promote bone healing in rat calvarial defect model, Liu B, Li J, Lei X, Cheng P, Song Y, Gao Y, Hu J, Wang C, Zhang S, Li D, Wu H, Sang H, Bi L, Pei G, 2020 Zinc Silicate/Nano-Hydroxyapatite/Collagen Scaffolds Promote Angiogenesis and Bone Regeneration via the p38 MAPK Pathway in Activated Monocytes, Song Y, Wu H, Gao Y, Li J, Lin K, Liu B, Lei X, Cheng P, Zhang S, Wang Y,Sun J, Bi L, Pei G, 2020 Effects of cyclic fluid stress at different frequencies on behaviors of cells incubated on titanium alloy, Lei X, Wu H, Song Y, Liu B, Zhang S, Li J, Bi L, Pei G, 2020 Blockade of adrenergic β‐receptor activation through local delivery of propranolol from a 3D collagen/polyvinyl alcohol/hydroxyapatite scaffold promotes bone repair in vivo, Wu H, Song Y, Li J, Lei X, Zhang S, Gao Y, Cheng P, Liu B, Miao S, Bi L, Yang L, Pei G, 2020 The effect of fluid shear stress on fibroblasts and stem cells on plane and groove topographies, Lei X, Liu B, Wu H, Wu X, Wang X, Song Y, Zhang S, Li J, Bi L, Pei G, 2020 Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling, Li D, Cheng P, Jiang H, Cao T, Wang J, Gao Y, Lin Y, Wang C, Zhang S, Li J, Liu B, Song Y, Yang L, Pei G

Areas of Focus

Regenerative Orthopedic Research
Intelligent and Digital Orthopedics

Publications

Microgroove Cues Guiding Fibrogenesis of Stem Cells via Intracellular Force, Lei X, Miao S, Wang X, Gao Y, Wu H, Cheng P, Song Y, Bi L, Pei G, 2023
Fractional differential equation modeling of the HBV infection with time delay and logistic proliferation, Sun D, Liu J, Su X, Pei G, 2022
Cefazolin/BMP-2-Loaded Mesoporous Silica Nanoparticles for the Repair of Open Fractures with Bone Defects, Mingkui Shen, Lulu Wang, Li Feng, Chuangye Xu, Yi Gao, Sijing Li, Yulan Wu, Guoxian Pei, 2022
Distal Humerus Morphological Analysis of Chinese Individuals: A Statistical Shape Modeling Approach, Zhao W, Guo Y, Xu C, Pei G, Basnet S, Pei Y, Su X, 2022
3D bioprinting of in situ vascularized tissue engineered bone for repairing large segmental bone defects, Mingkui Shen, Lulu Wang, Yi Gao, Li Feng, Chuangye Xu, Sijing Li, Xiaohu Wang, Yulan Wu, Yao Guo, Guoxian Pei, 2022
A 3D bioprinted nano-laponite hydrogel construct promotes osteogenesis by activating PI3K/AKT signaling pathway, Sheng Miao, Jinru Zhou, Bin Liu, Xing Lei, Taoran Wang, Xiaotian Hao, Pengzhen Cheng, Hao Wu, Yue Song, Guoxian Pei, Long Bi, 2022
bFGF-Loaded Mesoporous Silica Nanoparticles Promote Bone Regeneration Through the Wnt/β-Catenin Signalling Pathway, Mingkui Shen, Lulu Wang, Li Feng, Yi Gao, Sijing Li, Yulan Wu, Chuangye Xu, Guoxian Pei, 2022
Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion, Pengzhen Cheng, Tianqing Cao, Xueyi Zhao, Weiguang Lu, Sheng Miao, Fenru Ning, Dong Wang, Yi Gao,Long Wang, Guoxian Pei, and Liu Yang, 2022
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro, Li JQ, Jiang HJ, Su XY, Feng L, Zhan NZ, Li SS, Chen ZJ, Chang BH, Cheng PZ, Yang L, Pei GX, 2022
Fabrication of a bio-instructive scaffold conferred with a favorable microenvironment allowing for superior implant osseointegration and accelerated in situ vascularized bone regeneration via type H vessel formation, Yijun He, Wenhao Wang, Shaozhang Lin, Yixi Yang, Lizhi Song, Yihan Jing, Lihao Chen, Zaopeng He, Wei Li, Ao Xiong, Kelvin W.K. Yeung , Qi Zhao, Yuan Jiang, Zijie Li, Guoxian Pei, Zhi-Yong Zhang, 2022
Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells, Zhang Xinxin, Jiang Xiaorui, Jiang Shan, Cai Xiyu, Yu Shengji, Pei Guoxian, 2021
Cell-loaded injectable gelatin/alginate/LAPONITE® nanocomposite hydrogel promotes bone healing in a critical-size rat calvarial defect model, Liu B, Li J, Lei X, Miao S, Zhang S, Cheng P, Song Y, Wu H, Gao Y, Bi L, Pei G, 2020
3D-bioprinted functional and biomimetic hydrogel scaffolds incorporated with nanosilicates to promote bone healing in rat calvarial defect model, Liu B, Li J, Lei X, Cheng P, Song Y, Gao Y, Hu J, Wang C, Zhang S, Li D, Wu H, Sang H, Bi L, Pei G, 2020
Zinc Silicate/Nano-Hydroxyapatite/Collagen Scaffolds Promote Angiogenesis and Bone Regeneration via the p38 MAPK Pathway in Activated Monocytes, Song Y, Wu H, Gao Y, Li J, Lin K, Liu B, Lei X, Cheng P, Zhang S, Wang Y,Sun J, Bi L, Pei G, 2020
Effects of cyclic fluid stress at different frequencies on behaviors of cells incubated on titanium alloy, Lei X, Wu H, Song Y, Liu B, Zhang S, Li J, Bi L, Pei G, 2020
Blockade of adrenergic β‐receptor activation through local delivery of propranolol from a 3D collagen/polyvinyl alcohol/hydroxyapatite scaffold promotes bone repair in vivo, Wu H, Song Y, Li J, Lei X, Zhang S, Gao Y, Cheng P, Liu B, Miao S, Bi L, Yang L, Pei G, 2020
The effect of fluid shear stress on fibroblasts and stem cells on plane and groove topographies, Lei X, Liu B, Wu H, Wu X, Wang X, Song Y, Zhang S, Li J, Bi L, Pei G, 2020
Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling, Li D, Cheng P, Jiang H, Cao T, Wang J, Gao Y, Lin Y, Wang C, Zhang S, Li J, Liu B, Song Y, Yang L, Pei G

Regeneration Orthopedics Tissue Engineering Limb Trauma Digital Technology Surgical Innovation Bone Repair Clinical Research Biomedical Engineering Transplantation

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