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Lin Wang
Medical School
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Metabolism
Lipids
Glucose
Bone Disease
Pathogenesis
Implants
Biomaterials
Surface Interaction
Tissue Engineering
Regeneration
Areas of Focus
- Metabolic dysregulation in bone disease
- Bone implant material surface interfaces and biological behavior
- Bone tissue engineering and regenerative medicine
Work Experience
- 2000-2008 Resident Physician/Assistant, Department of Orthopedics, Xijing Hospital, Fourth Military Medical University
- 2008-2016 Attending Physician/Lecturer, Department of Orthopedics, Xijing Hospital, Fourth Military Medical University
- 2015-2016 Master's Supervisor, Department of Orthopedics, Xijing Hospital, Fourth Military Medical University
- 2016-2018 Associate Chief Physician/Associate Professor/Master's Supervisor, First Affiliated Hospital of Xi'an Jiaotong University
- 2018-present Researcher/Associate Professor/Doctoral Supervisor, Southern University of Science and Technology
- 2018-present Deputy Dean/Chief Physician of Spinal Surgery, Southern University of Science and Technology Hospital
Academic Background & Achievements
- 1995-2000 Bachelor in Clinical Medicine, Fourth Military Medical University
- 2002-2005 Master's in Orthopedics, Xijing Hospital, Fourth Military Medical University
- 2005-2008 PhD in Orthopedics, Xijing Hospital, Fourth Military Medical University
- Hosted two National Natural Science Foundation projects
- Published 28 SCI papers and 40 core journal papers
- Holds 3 national invention patents and 2 utility model patents
- Trained 5 PhD and 5 Master's students
Publications
- ROS-reactive PMS/PC drug delivery system improves new bone formation under diabetic conditions by promoting angiogenesis-osteogenesis coupling via down-regulating NOX2-ROS signalling axis, Z. Wu, Q. Hou, T. Chen, X. Jiang, L. Wang, J. Xu, L. Wang, 2023
- 3D printing of reduced glutathione grafted gelatine methacrylate hydrogel scaffold promotes diabetic bone regeneration by activating PI3K/Akt signaling pathway, L. Wang, M. Shen, Q. Hou, Z. Wu, J. Xu, L. Wang, 2022
- The dual-effects of PLGA@MT electrospun nanofiber coatings on promoting osteogenesis at the titanium-bone interface under diabetic conditions, Z. Wang, T. Chen, Z. Wu, X. Jiang, Q. Hou, S. Miao, R. Xia, L. Wang, 2022
- Promotion of osteointegration under diabetic conditions by a silk fibroin coating on 3D-printed porous titanium implants via a ROS-mediated NF-kappaB pathway, X.Y. Ma, T.C. Ma, Y.F. Feng, G. Xiang, W. Lei, D.P. Zhou, H.L. Yu, L.B. Xiang, L. Wang, 2021
- Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone, X.F. Hu, Y.F. Feng, G. Xiang, W. Lei, L. Wang, 2018
- Evaluation of an artificial vertebral body fabricated by a tantalum-coated porous titanium scaffold for lumbar vertebral defect repair in rabbits, F. Wang, L. Wang, Y. Feng, X. Yang, Z. Ma, L. Shi, X. Ma, J. Wang, T. Ma, Z. Yang, X. Wen, Y. Zhang, W. Lei, 2018
- Angiogenesis impairment by the NADPH oxidase-triggered oxidative stress at the bone-implant interface: Critical mechanisms and therapeutic targets for implant failure under hyperglycemic conditions in diabetes, X.F. Hu, L. Wang, Y.Z. Lu, G. Xiang, Z.X. Wu, Y.B. Yan, Y. Zhang, X. Zhao, Y. Zang, L. Shi, W. Lei, Y.F. Feng, 2018
- Adiponectin improves the osteointegration of titanium implant under diabetic conditions by reversing mitochondrial dysfunction via the AMPK pathway in vivo and in vitro, X.F. Hu, L. Wang, Y.Z. Lu, G. Xiang, Z.X. Wu, Y.B. Yan, Y. Zhang, X. Zhao, Y. Zang, L. Shi, W. Lei, Y.F. Feng, 2017
- Magnesium Ions Promote the Biological Behaviour of Rat Calvarial Osteoblasts by Activating the PI3K/Akt Signalling Pathway, J. Wang, X.Y. Ma, Y.F. Feng, Z.S. Ma, T.C. Ma, Y. Zhang, X. Li, L. Wang, W. Lei, 2017
- Involvement of FAK-mediated BMP-2/Smad pathway in mediating osteoblast adhesion and differentiation on nano-HA/chitosan composite coated titanium implant under diabetic conditions, X.Y. Ma, Y.F. Feng, T.S. Wang, W. Lei, X. Li, D.P. Zhou, X.X. Wen, H.L. Yu, L.B. Xiang, L. Wang, 2017
Awards
- 2011: Shandong Province Science and Technology Progress Second Prize
- 2012: Completed the first domestic large animal bone implant experiment using 3D printed titanium alloy stents
- 2014: Performed the first national Mazor Renaissance robotic cervical surgery
- 2013: Chinese Orthopedic Association Young Scientist Second Prize
- 2016: Chinese Medical Association Second Prize for Medical Science and Technology
- 2017: Chinese Association of Orthopedic Surgeons Standardized Surgery Video Contest Second Prize
