Areas of Focus
- Viral hepatitis translational research
- Antiviral drug development
- Host-virus interactions
- Natural immune response mechanisms
- Clinical cohort studies on hepatitis E
- Mitochondrial dynamics in sepsis
- Non-infectious liver diseases
- Invasive diagnostic markers for liver diseases
Work Experience
- 2020/11-Present, Southern University of Science and Technology, School of Medicine, Associate Professor
- 2016/09-2020/10, PLA General Hospital Fifth Medical Center, Pathology Diagnosis and Research Center, Associate Researcher
Academic Background & Achievements
- 2012/11–2016/09, Erasmus University Medical Center, Hepatology, PhD
- 2010/09–2012/08, Wageningen University & Research Center, Biotechnology Medicine, Master
- 2006/09–2010/07, Nanjing Medical University, Biotechnology, Bachelor
Publications
- TMBIM6 prevents VDAC1 multimerization and improves mitochondrial quality control to reduce sepsis-related myocardial injury, Zhou H, Dai Z, Li J, Wang J, Zhu H, Chang X, Wang Y*, 2023
- Serine/threonine kinase 3 promotes oxidative stress and mitochondrial damage in septic cardiomyopathy through inducing Kelch-like ECH-associated protein 1 phosphorylation and nuclear factor erythroid 2-related factor 2 degradation, Zhu H, Dai Z, Liu X, Zhou H, Wang Y*, 2023
- Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol-related liver disease by restoring p62-mediated mitophagy, Li R, Dai Z, Liu X, Wang C, Huang J, Xin T, Tong Y, Wang Y*, 2023
- The role and mechanism of action of mitophagy in various liver diseases, Wang C, Wang Y*, 2022
- Hepatitis E virus infection activates NLRP3 inflammasome antagonizing interferon response but therapeutically targetable, Li Y, Yu P, Kessler AL, Shu J, Liu X, Liang Z, Wang Y*, Pan Q*, 2022
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome, Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, 2020
- SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19, Wang Y, Liu S, Liu H, Li W, Lin F, Jiang L, 2020
- Calcineurin inhibitors stimulate and mycophenolic acid inhibits replication of hepatitis E virus, Wang Y, Zhou X, Debing Y, Chen K, Van Der Laan LJ, Neyts J, 2014
- Chronic Hepatitis E in a Renal Transplant Recipient: The First Report of Genotype 4 Hepatitis E Virus Caused Chronic Infection in Organ Recipient, Wang Y, Chen G, Pan Q, Zhao J, 2018
- Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids, Li P, Li Y, Wang Y, Liu J, Lavrijsen M, Li Y, 2022
- Detection of residual HCV-RNA in patients who have achieved sustained virological response is associated with persistent histological abnormality, Wang Y, Rao H, Chi X, Li B, Liu H, Wu L, 2019
- Hepatitis E virus infection in acute non-traumatic neuropathy: A large prospective case-control study in China, Wang Y, Wang S, Wu J, Jiang Y, Zhang H, Li S, 2018
- Incidence, predictors and prognosis of genotype 4 hepatitis E related liver failure: A tertiary nested case-control study, Wang Y, Liu H, Liu S, Yang C, Jiang Y, Wang S, 2019
- Nonalcoholic fatty liver disease is associated with lower hepatitis B viral load and antiviral response in pediatric population, Wang L, Wang Y, Liu S, Zhai X, Zhou G, Lu F, 2019
- Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication, Wang Y, Wang W, Xu L, Zhou X, Shokrollahi E, Felczak K, 2016
- Poor Outcomes of Acute Hepatitis E in Patients With Cirrhotic Liver Diseases Regardless of Etiology, Wang Y, Metselaar HJ, Peppelenbosch MP, Pan Q, 2020
- Chronic hepatitis E in solid-organ transplantation: the key implications of immunosuppressants, Wang Y, Metselaar HJ, Peppelenbosch MP, Pan Q, 2014
- RDW, NLR and RLR in predicting liver failure and prognosis in patients with hepatitis E virus infection, Wu J, Zhang X, Liu H, Guo N, Pan Q, Wang Y, 2019
- Chronic hepatitis E in an immunocompetent patient, Wang Y, Liu S, Pan Q, Zhao J, 2019
- Mitochondrial DNA from hepatocytes induces upregulation of interleukin-33 expression of macrophages in nonalcoholic steatohepatitis, Gao Y, Wang Y, Liu H, Liu Z, Zhao J, 2020
- Corticosteroid plus glycyrrhizin therapy for chronic drug- or herb-induced liver injury achieves biochemical and histological improvements: A randomised open-label trial, Wang J, Huang A, Wang Y, Ji D, Liang Q, Zhao J, 2022
- Clinical and pathological investigation of patients
Awards
- 2021: Chinese Medical Science and Technology Award, Third Prize in Medical Science and Technology
- 2020: Travel Award by Asia-Pacific Hepatology Society (APASL)
- 2019: Beijing Science and Technology Rising Star by Beijing Municipal Science and Technology Commission
- 2019: Innovative Talent Construction Engineering Talent by PLA General Hospital
- 2019: Young Scholar Award by European Association for the Study of the Liver (EASL)
- 2019: Excellent Paper Award at Beijing Liver Disease Conference by Beijing Medical Association
- 2018: Young Scholar Award by European Association for the Study of the Liver (EASL)
- 2018: Young Scholar Award by Asia-Pacific Hepatology Society (APASL)
- 2018: Excellent Paper Award at Beijing Liver Disease Conference by Beijing Medical Association
- 2017: Veldhovenbeurs Award by Dutch Hepatology Society (NVGE)
- 2017: Excellent Paper at Joint Academic Conference on Fatty Liver Disease by Chinese Medical Association
- 2017: Excellent Paper at Beijing Liver Disease Academic Conference by Beijing Medical Association
- 2014: Young Scholar Award by European Association for the Study of the Liver (EASL)