Areas of Focus
- Skeletal development and diseases
- Cartilage development and metabolism
- Hypoxia mechanisms in bone development
- Function and mechanisms of hypoxia-inducible factors (HIFs)
- Metabolic mechanisms in osteoarthritis
- Interaction between ER stress signaling and hypoxia signaling pathways in chondrocytes
Work Experience
- 2020.05-present, Southern University of Science and Technology, Medical School, Assistant Research Professor
- 2015.05-2017.10, University of Michigan, Medical School, Postdoctoral Research Fellow
- 2009.08-2010.08, Sun Yat-sen University, Bioengineering Center, Research Assistant
Academic Background & Achievements
- 2010.09-2015.02 PhD: University of Hong Kong, Faculty of Medicine
- 2006.09-2009.06 Master's: Sun Yat-sen University, School of Life Sciences
- 2002.09-2006.06 Bachelor's: Central China Normal University, School of Life Sciences
Publications
- In vivo survival strategies for cellular adaptation to hypoxia: HIF1α-dependent suppression of mitochondrial oxygen consumption and decrease of intracellular hypoxia are critical for survival of hypoxic chondrocytes., Yao Q., Parvez Khan M, Schipani E., 2020
- Suppressing mitochondrial respiration is critical for hypoxia tolerance in the fetal growth plate., Yao, Q., Parvez Khan M, Merceron C, LaGory E, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E., 2019
- Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual., Merceron, C., Ranganathan, K., Wang, E., Tata, Z., Makkapati, S., Khan, M. P., Mangiavini, L., Yao, A. Q., Castellini, L., Levi, B., Giaccia, A. J., Schipani, E., 2019
- Label-Free Quantitative Proteomics Reveals Survival Mechanisms developed by hypertrophic chondrocytes under ER stress., Kudelko M., Chan C.W., Sharma R., Yao Q., Lau, E., Chu, I.K., Cheah, K.S.E., Tanner, J.A. and Chan, D., 2016
- Hox11 genes regulate postnatal longitudinal bone growth and growth plate proliferation., Pineault KM., Swinehart IT.,Garthus KN., Ho E., Yao Q., Schipani E., Kozloff KM.,Wellik DM., 2015
- Microrna-195 Plays a Tumor-Suppressor Role in Human Glioblastoma Cells by Targeting Signaling Pathways Involved in Cellular Proliferation and Invasion., Zhang, Q. Q., H. Xu, M. B. Huang, L. M. Ma, Q. J. Huang, Yao, Q., H. Zhou, and L. H. Qu., 2012
- Microrna-21 Promotes Cell Proliferation and Down-Regulates the Expression of Programmed Cell Death 4 (Pdcd4) in Hela Cervical Carcinoma Cells., Yao, Q., H. Xu, Q. Q. Zhang, H. Zhou, and L. H. Qu., 2009
- The Structure, Function and Evolution of Baculoviral Inhibitor of Apoptosis Gene., Zhang R, Yao Q, Peng JX, Hong HZ, 2006
- Cloning and Expression of Ubiquitin Gene of Helicoverpa armigera Single-nucleocapsid Nucleopolyhedrovirus and its Antiserum Preparation., Li JJ, Yao Q, Yang DY, Yu ZH, Chen XW, 2005
Awards
- ASBMR Young Investigator Award, 2015 (American Society for Bone and Mineral Research, Young Investigator Award)