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Jian Zhang
zhangjian@sustech.edu.cn
English, Chinese
Guangdong
Southern University of Science and Technology
Medical School
  • 1981-1986: Bachelor in Clinical Medicine, Tianjin Medical University
  • 1997-1998: Master in Immunology, Old Dominion University & East Virginia Medical School
  • 1998-2001: PhD in Pathology, University of Michigan
  • Selected as a national candidate for the 'Millions of Talents Project' in 2014
  • 1986.8-1995.1: Tianjin Third Hospital/Tianjin Institute of Geriatric Medicine, Resident Physician, Attending Physician
  • 1995.1-1996.8: University of Wisconsin-Madison, Geriatric Medicine Institute, WHO Scholarship Visiting Scholar
  • 1996.8-1998.8: East Virginia Medical School, Geriatric Medicine Research Center, Visiting Research Scientist
  • 1998.8-2004.6: University of Michigan Medical School, PhD Student/Researcher
  • 2004.7-2010.12: University of Pittsburgh and University of Michigan Medical School, Assistant Professor (Tenure track)
  • 2011.1-2016.7: Key Laboratory of Longevity and Ageing-related Diseases, Guangxi Medical University, Director/Professor
  • 2016.3-: University of Pittsburgh Medical School, Part-time Professor
  • 2016.7-: Southern University of Science and Technology, Professor
  • 2019: Vice President of Shenzhen Biopharmaceutical Promotion Association
  • 2018: Vice Chairman of Shenzhen Alliance of China Cancer Prevention and Treatment Alliance
  • 2014: Expert with Special Government Allowance of the State Council
  • 2013: National candidate for the 'Millions of Talents Project' and awarded 'Outstanding Young Expert'
  • 2013: International lecturer certificate by the American Basic Urological Research Society (SBUR)
  • 2012: National Excellent Science and Technology Worker
  • 2011: Bagui Scholar of Guangxi Zhuang Autonomous Region, Consultant of the Government of Guangxi Zhuang Autonomous Region
  • 2007: Mentoring Dr. Yi Lu, Young Investigator Travel Award, ASBMR
  • 2005: Mentoring Dr. Yi Lu, Scholar-in-Training Award, AACR
  • 2003: Scholar-in-Training Award, AACR
  • 2003: Plenary Poster Award of 25th Annual Meeting of American Society for Bone and Mineral Research
  • 2002: Alice L. Jee Memorial Young Investigator Award
  • 2000: Plenary Poster Award of 22nd Annual Meeting of American Society for Bone and Mineral Research
  • 1994: Fellowship Award, World Health Organization (WHO)
Tumor transformation medical research
Tumor resistance, recurrence, and metastasis
Aging and cancer
  • Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone, Zhang J, Dai J, Qi Y, Lin D, Smith P, Strayhorn C, Mizokami A, Fu Z, Westman J, Keller ET, 2001
  • Oxidative stress-mediated activation of NFkB and the interleukin-6 promoter requires NFkB-inducing kinase activity, Zhang J, Johnston G, Stebler B, Keller ET, 2001
  • Osteoprotegerin abrogates chronic alcohol ingestion-induced bone loss in mice, Zhang J, Dai J, Lin D, Habib P, Smith P, Murtha J, Fu Z, Yao Z, Qi Y, Keller ET, 2002
  • Soluble RANK-Fc diminishes prostate tumor progression in bone, Zhang J, Dai J, Yao Z, Lu Y, Dougall W, Keller ET, 2003
  • Bioluminescence imaging of RANK ligand transcriptional regulation in vivo, Zhang J, Lu Y, Kitazawa R, Kitazawa S, Dai J, Qi W, Zhao X, Yao Z, Hall D, Keller ET, 2004
  • In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging, Zhang J, Lu Y, Kitazawa R, Kitazawa S, Dai J, Qi W, Zhao X, Yao Z, Hall D, Ershler WB, Keller ET, 2004
  • Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion, Lu Y, Cai Z, Galson DL, Xiao G, Liu YL, George D, Melhem MF, Yao Z and Zhang J, 2006
  • Monocyte chemotactic protein-1 (MCP-1) mediates prostate cancer-induced bone resorption, Lu Y, Cai Z, Xiao G, Liu Y, Keller ET, Mizokami A, Yao Z, Roodman GD, Zhang J, 2007
  • CCR2 expression correlates with prostate cancer progression, Lu Y, Yao Z, and Zhang J, 2007
  • Prostate cancer bone metastasis: interaction between tumor cells and bone microenvironment, Lu Y, Yao Z, and Zhang J, 2007
  • PTHrP-induced MCP-1 production by human bone marrow endothelial cells promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro, Lu Y, Xiao G, Galson DL, Nishio Y, Mizokami A, Yao Z, and Zhang J, 2007
  • Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3β phosphorylation, Lu Y, Nie DB, Witt WT, Chen Q, Shen M, Xie H, Lai L, Dai Y, Zhang J, 2008
  • CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro, Lu Y, Wang J, Xu Y, Koch AE., Cai Z, Chen X, Galson DL, Taichman RS, and Zhang J, 2008
  • Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone, Cai Z, Chen QY, Chen J, Lu Y, Xiao GZ, and Zhang J, 2009
  • MCP-1 promotes lung cancer-induced bone resorptive lesions in vivo, Cai Z, Chen QY, Chen J, Lu Y, Xiao GZ, and Zhang J, 2009
Tumor Transformation Medical Research Resistance Recurrence Metastasis Aging Cancer Pathology Treatment Therapy Clinical Gerontology Health

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