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Xiaohui Zhou
Medical School
Southern University of Science and Technology
Guangdong
Language: Chinese, English
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Pathogens Host Interaction Molecular Mechanisms Pathogenesis Vaccines Infectious Diseases Antibiotic Resistance Anti-Infective Drugs Drug Development Microbiology
Areas of Focus
  • Pathogenic microorganisms and host interactions and molecular mechanisms of pathogenesis
  • Development and research of infectious disease vaccines
  • Antibiotic resistance mechanisms and development of new anti-infective drugs
Work Experience
  • 2022 – Present: Southern University of Science and Technology - Professor
  • 2013 – 2022: University of Connecticut, Department of Pathobiology - Assistant Professor, Associate Professor, Tenured Professor, Researcher (PI)
  • 2010 – 2013: Harvard Medical School/HHMI - Research Assistant
  • 2008 – 2010: Washington State University - Postdoctoral Researcher
Academic Background & Achievements
  • 2008 - PhD in Microbiology: Washington State University
  • Selected for the National High-level Talent Plan
Publications
  • Ferric chloride induces ferroptosis in Pseudomonas aeruginosa and heals wound infection in a mouse model, Zhou X*, 2023
  • Ferrous sulfate-loaded hydrogel cures Staphylococcus aureus infection via facilitating a ferroptosis-like bacterial cell death in a mouse keratitis model, Zhou X*, 2022
  • Nucleolar c-Myc recruitment by a Vibrio T3SS effector promotes host cell proliferation and bacterial virulence, Zhou X*, 2021
  • S-nitrosylation mediated activation of a histidine kinase represses T3SS1 gene expression and promotes virulence of an enteric pathogen, Zhou X*, 2020
  • Identification of the first tail tubular proteins receptor that mediates phage adsorption to a marine pathogen Vibrio parahaemolyticus, Zhou X*, 2020
  • A σE-mediated temperature gauge controls a switch from LuxR-mediated virulence gene expression to thermal stress adaptation in Vibrio alginolyticus, Zhou X*, 2016
  • A sensor histidine kinase is a beta-lactam receptor and induces resistance to beta-lactam, Zhou X*, 2016
  • A Vibrio parahaemolyticus type III effector mediates pathogenesis by independently enabling intestinal colonization and inhibiting TAK1 activation, Zhou X, 2013
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