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Cheng Longzhen
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Chronic Pain
Chronic Itch
Central Neural Circuits
Opioids
Pain Sensitization
Spinal Circuits
Somatosensory
Neural Regulation
Mechanisms
Neurobiology
Areas of Focus
- Central neural circuits of chronic pain and chronic itch
- Neural circuit mechanisms of pain sensitization caused by opioids
- Spinal neural circuits and their regulatory mechanisms of somatosensory
Work Experience
- 2018 – Present: Southern University of Science and Technology, Department of Biology, Assistant Professor
- 2016 – 2017: Fudan University Brain Science Institute, Associate Researcher
- 2013 – 2016: Harvard Medical School, Postdoctoral Researcher
- 2009 – 2013: Fudan University Brain Science Institute, Assistant Researcher
Academic Background & Achievements
- 2005 – 2009 PhD in Neurobiology: Fudan University
- 2002 – 2005 Master in Physiology: Wannan Medical College
- 1997 – 2002 Bachelor in Clinical Medicine: Wannan Medical College
- Postdoctoral Researcher at Harvard Medical School
Publications
- Identification of spinal circuits involved in touch-evoked dynamic mechanical pain, Cheng L, et al., 2017
- Identification of spinal circuits transmitting and gating mechanical pain, Cheng L, et al., 2014
- Spinal circuits transmitting mechanical pain and itch, Cheng L, et al., 2017
- Gate control of mechanical itch by a subpopulation of spinal cord interneurons, Cheng L, et al., 2015
- (R)-alpha-methylhistamine Suppresses Inhibitory Neurotransmission in Hippocampal CA1 Pyramidal Neurons Counteracting Propofol-Induced Amnesia in Rats, Cheng L, et al., 2014
- Activation of extrasynaptic GABA(A) receptors inhibits cyclothiazide-induced epileptiform activity in hippocampal CA1 neurons, Cheng L, et al., 2014
- Involvement of ryanodine receptors in tetanic sciatic stimulation-induced long term potentiation of spinal dorsal horn and persistent pain in rats, Cheng L, et al., 2012
- Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord, Cheng L, et al., 2012
- Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559, Cheng L, et al., 2011
- Ryanodine receptors contribute to the induction of nociceptive input-evoked long-term potentiation in the rat spinal cord slice, Cheng L, et al., 2010
