Professor | Xin Gong | Asia Growth Partners

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Name	Xin Gong
Contact Information	gongx@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Xin Gong

Contact Information

gongx@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2010-2015 PhD: Tsinghua University, School of Life Sciences 2006-2010 Bachelor: Huazhong University of Science and Technology, School of Life Science and Technology Published as first author or corresponding author in top international journals such as Cell and Science
Work Experience	2019-present Southern University of Science and Technology, Department of Biology, Associate Professor 2017-2018 Princeton University, Department of Molecular Biology, Postdoctoral Researcher 2015-2017 Tsinghua University, School of Medicine, Postdoctoral Researcher
Awards	2019 Guangdong Province 'Outstanding Young Scientist Fund' 2019 Shenzhen High-level Talent (National Leading Talent) 2019 Shenzhen Overseas High-level Talent (Category B)

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2010-2015 PhD: Tsinghua University, School of Life Sciences
2006-2010 Bachelor: Huazhong University of Science and Technology, School of Life Science and Technology
Published as first author or corresponding author in top international journals such as Cell and Science

Work Experience

2019-present Southern University of Science and Technology, Department of Biology, Associate Professor
2017-2018 Princeton University, Department of Molecular Biology, Postdoctoral Researcher
2015-2017 Tsinghua University, School of Medicine, Postdoctoral Researcher

Awards

2019 Guangdong Province 'Outstanding Young Scientist Fund'
2019 Shenzhen High-level Talent (National Leading Talent)
2019 Shenzhen Overseas High-level Talent (Category B)

Areas of Focus	Structural biology research methods, biochemistry, and biophysics to study proteins involved in cholesterol and lipid metabolism regulation pathways related to major diseases
Publications	Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm, Qian H, Cao P, Hu M, Gao S, Yan N#, Gong X#, 2019 Structural basis for the recognition of Sonic Hedgehog by human Patched1, Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N#, 2018 Structure of the human lipid exporter ABCA1, Qian H, Zhao X, Cao P, Lei J, Yan N#, and Gong X, 2017 Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization, Gong X, Qian H, Shao W, Li J, Wu J, Liu J, Li W, Wang H, Espenshade P#, Yan N#, 2016 Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection, Gong X, Qian H, Zhou X, Wu J, Wan T, Cao P, Huang W, Zhao X, Wang X, Wang P, Shi Y, Gao GF, Zhou Q#, Yan N#, 2016 Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition, Gong X, Li J, Shao W, Wu J, Qian H, Ren R, Espenshade P#, Yan N#, 2015

Areas of Focus

Structural biology research methods, biochemistry, and biophysics to study proteins involved in cholesterol and lipid metabolism regulation pathways related to major diseases

Publications

Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm, Qian H*, Cao P*, Hu M, Gao S, Yan N#, Gong X#, 2019
Structural basis for the recognition of Sonic Hedgehog by human Patched1, Gong X*, Qian H*, Cao P*, Zhao X, Zhou Q, Lei J, Yan N#, 2018
Structure of the human lipid exporter ABCA1, Qian H*, Zhao X, Cao P, Lei J, Yan N#, and Gong X*, 2017
Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization, Gong X*, Qian H*, Shao W*, Li J, Wu J, Liu J, Li W, Wang H, Espenshade P#, Yan N#, 2016
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection, Gong X*, Qian H*, Zhou X*, Wu J*, Wan T*, Cao P, Huang W, Zhao X, Wang X, Wang P, Shi Y, Gao GF, Zhou Q#, Yan N#, 2016
Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition, Gong X*, Li J*, Shao W*, Wu J, Qian H, Ren R, Espenshade P#, Yan N#, 2015

Structural Biology Biochemistry Biophysics Cholesterol Metabolism Lipid Metabolism Disease-Related Pathways Protein Structure Protein Function Metabolic Regulation Disease Mechanisms

Fang Yu - Shanghai Normal University

Lu Qing - Shanghai Jiao Tong University

Geng Wu - Shanghai Jiao Tong University

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