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Hongda Huang
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Dna Methylation
Demethylation
Histone Modification
Chromatin Remodeling
Histone Variants
Gene Transcription
Dna Replication
Dna Repair
Cell Development
Disease Mechanisms
Areas of Focus
- Epigenetics
Work Experience
- 2017-present Associate Professor, Department of Biology, Southern University of Science and Technology
- 2011-2017 Postdoctoral Researcher, Memorial Sloan-Kettering Cancer Center
Academic Background & Achievements
- 2004-2010 PhD in Life Sciences, University of Science and Technology of China
- Doctoral supervisors: Academician Shi Yunyu and Professor Wu Jihui
Publications
- Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex, Na Wang, Christophe Bosc, Sung Ryul Choi, Benoit Boulan, Leticia Peris, Natacha Olieric, Hongyu Bao, Fatma Krichen, Liu Chen, Annie Andrieux, Vincent Olieric, Marie-Jo Moutin, Michel O. Steinmetz, Hongda Huang, 2019
- Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis, Shanhui Liao, Girish Rajendraprasad, Na Wang, Susana Eibes, Jun Gao, Huijuan Yu, Gao Wu, Xiaoming Tu, Hongda Huang, Marin Barisic, Chao Xu, 2019
- Structural Basis Underlying Viral Hijacking of a Histone Chaperone Complex, Huang H., Deng Zh., Vladimirova O., Wiedmer A., Lu F., Lieberman P., Patel D.J., 2016
- H4 K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex, Saredi G., Huang H., Hammond C., Bekker-Jensen S., Forne I., Reverón-Gómez N., Foster B., Mlejnkova L., Bartke T., Cejka P., Mailand N., Imhof A., Patel D., Groth A., 2016
- A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks, Huang H., Strømme C.B., Saredi G., Hödl M., Strandsby A., González-Aguilera C., Chen Sh., Groth A., Patel D.J., 2015
- DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition, Elsasser S.J., Huang H., Lewis P.W., Chin J.W., Allis C.D., Patel D.J., 2012
