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Dan Huang
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Genomics
Evolution
Transcription
Regulation
Tumor
Metabolism
Oncology
Bioinformatics
Data Analysis
Molecular Biology
Areas of Focus
- Genomic Evolution
- Tumor Metabolism
- Transcriptional Regulation Mechanisms
Work Experience
- 2023 - Present, Southern University of Science and Technology, Department of Basic Immunology and Microbiology, Research Assistant Professor
- 2021 - 2023, Southern University of Science and Technology, Department of Systems Biology, Postdoctoral Researcher
- 2020 - 2021, Cell Atlas Ltd., Chief Scientist
- 2019 - 2020, The Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Postdoctoral Researcher
- 2013 - 2014, The Chinese University of Hong Kong Shenzhen Research Institute, Research Assistant
Academic Background & Achievements
- 2014 - 2018 PhD in Chemical Pathology: The Chinese University of Hong Kong
- 2008 - 2013 Bachelor in Bioinformatics: Harbin Medical University
Publications
- METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy, Pan Y, Chen H, Zhang X, Liu W, Ding Y, Huang D, Zhai J, Wei W, Wen J, Chen D, Zhou Y, Liang C, Wong N, Man K, Cheung AH, Wong CC, Yu J, 2023
- Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice, Li Q, Chan H, Liu WX, Liu CA, Zhou Y, Huang D, ... & Yu J, 2023
- Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer, Bao Y, Zhai J, Chen H, Wong C, Liang C, Ding Y, Huang D, ... & Yu, J, 2023
- METTL3 inhibits anti-tumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer, Chen, H., Pan, Y., Zhou, Q., Liang, C., Wong, C. C., Zhou, Y.,Huang, D. ... & Yu, J, 2022
- Nonsense-Mediated Decay Targeted RNA (ntRNA): Proposal of a ntRNA-miRNA-lncRNA Triple Regulatory Network Usable as Biomarker of Prognostic Risk in Patients with Kidney Cancer, Zhou Z, Hu F, Huang D, Chi Q, Tang NLS, 2022
- 3′ untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance, Huang, D.*, Wang, X.*., Huang, Z., Liu, Y., Liu, X., Gin, T., ... & Wu, W. K. K, 2022
- Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution, Wang, X., Hu, W., Li, X., Huang, D., Li, Q., Chan, H., Zeng, J., Xie, C., Chen, H., Liu, X. and Gin, T, 2022
- Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients, Wang, X., Cheng, F.T., Lam, T.Y., Liu, Y., Huang, D., Liu, X., Chen, H., Zhang, L., Ali, Y., Wang, M.H. and Yu, J, 2022
- Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients, Liu Y, Ling L, Wong SH, Wang MH, Fitzgerald JR, Zou X, Fang S, Liu X, Wang X, Hu W, Chan H, Wang Y, Huang D, Li Q, Wong WT, Choi G, Zou H, Hui DS, Yu J, Tse G, Gin T, Wu WK, Chan MT, Zhang L, 2021
- Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance, Huang, D*., Wang, X*., Liu, Y., Huang, Z., Hu, X., Hu, W., Li, Q., Chan, H., Zou, Y., Ho, I.H. and Wang, Y, 2021
- Direct Measurement of B Lymphocyte Gene Expression Biomarkers in Peripheral Blood Transcriptomics Enables Early Prediction of Vaccine Seroconversion, Huang, D., Liu, A.Y., Leung, K.S. and Tang, N.L, 2021
- Peripheral Blood T Cell Gene Expression Responses to Exercise and HMB in Sarcopenia, Ma SL, Wu J, Zhu L, Chan RS, Wang X, Huang D, Tang NL, Woo J, 2021
- Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase, Li, Q., Hu, W., Liu, W.X., Zhao, L.Y., Huang, D., Liu, X.D., Chan, H., Zhang, Y., Zeng, J.D., Coker, O.O. and Kang, W, 2020
- Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets, Lee, K.Y., Leung, K.S., Ma, S.L., So, H.C., Huang, D., Tang, N.L.S. and Wong, M.H, 2020
- Ambient Temperature is A Strong Selective Factor Influencing Human Development and Immunity, Ji, L., Wu, D., Xie, H., Yao, B., Chen, Y., Irwin, D.M., Huang, D., Xu, J., Tang, N.L. and Zhang, Y, 2020
- Reference intervals of spot urine copper excretion in preschool children and potential application in pre-symptomatic screening of Wilson disease, Tang, N.L.S., Hui, J., Huang, D., Tang, M.F., Wang, X., Wu, J., Chan, I.H. and Leung, T.F, 2020
- Genetic susceptibility to Tuberculosis: Interaction between HLA-DQA1 and age of onset, Tang NL, Wang X, Chang KC, Chan CY, Szeto NW, Huang D, Wu J, Lui GC, Leung CC, Hui M, 2019
- Deciphering global signal features of high-throughput array data from cancers, Wu D, Kang J, Huang Y, Li X, Wang X, Huang D, Wang Y, Li B, Hao D, Gu Q, Tang N, 2014
