Professor | Dan Huang | Asia Growth Partners

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Name	Dan Huang
Contact Information	huangd@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Dan Huang

Contact Information

huangd@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2014 - 2018 PhD in Chemical Pathology: The Chinese University of Hong Kong 2008 - 2013 Bachelor in Bioinformatics: Harbin Medical University
Work Experience	2023 - Present, Southern University of Science and Technology, Department of Basic Immunology and Microbiology, Research Assistant Professor 2021 - 2023, Southern University of Science and Technology, Department of Systems Biology, Postdoctoral Researcher 2020 - 2021, Cell Atlas Ltd., Chief Scientist 2019 - 2020, The Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Postdoctoral Researcher 2013 - 2014, The Chinese University of Hong Kong Shenzhen Research Institute, Research Assistant

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2014 - 2018 PhD in Chemical Pathology: The Chinese University of Hong Kong
2008 - 2013 Bachelor in Bioinformatics: Harbin Medical University

Work Experience

2023 - Present, Southern University of Science and Technology, Department of Basic Immunology and Microbiology, Research Assistant Professor
2021 - 2023, Southern University of Science and Technology, Department of Systems Biology, Postdoctoral Researcher
2020 - 2021, Cell Atlas Ltd., Chief Scientist
2019 - 2020, The Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Postdoctoral Researcher
2013 - 2014, The Chinese University of Hong Kong Shenzhen Research Institute, Research Assistant

Areas of Focus	Genomic Evolution Tumor Metabolism Transcriptional Regulation Mechanisms
Publications	METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy, Pan Y, Chen H, Zhang X, Liu W, Ding Y, Huang D, Zhai J, Wei W, Wen J, Chen D, Zhou Y, Liang C, Wong N, Man K, Cheung AH, Wong CC, Yu J, 2023 Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice, Li Q, Chan H, Liu WX, Liu CA, Zhou Y, Huang D, ... & Yu J, 2023 Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer, Bao Y, Zhai J, Chen H, Wong C, Liang C, Ding Y, Huang D, ... & Yu, J, 2023 METTL3 inhibits anti-tumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer, Chen, H., Pan, Y., Zhou, Q., Liang, C., Wong, C. C., Zhou, Y.,Huang, D. ... & Yu, J, 2022 Nonsense-Mediated Decay Targeted RNA (ntRNA): Proposal of a ntRNA-miRNA-lncRNA Triple Regulatory Network Usable as Biomarker of Prognostic Risk in Patients with Kidney Cancer, Zhou Z, Hu F, Huang D, Chi Q, Tang NLS, 2022 3′ untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance, Huang, D., Wang, X.., Huang, Z., Liu, Y., Liu, X., Gin, T., ... & Wu, W. K. K, 2022 Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution, Wang, X., Hu, W., Li, X., Huang, D., Li, Q., Chan, H., Zeng, J., Xie, C., Chen, H., Liu, X. and Gin, T, 2022 Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients, Wang, X., Cheng, F.T., Lam, T.Y., Liu, Y., Huang, D., Liu, X., Chen, H., Zhang, L., Ali, Y., Wang, M.H. and Yu, J, 2022 Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients, Liu Y, Ling L, Wong SH, Wang MH, Fitzgerald JR, Zou X, Fang S, Liu X, Wang X, Hu W, Chan H, Wang Y, Huang D, Li Q, Wong WT, Choi G, Zou H, Hui DS, Yu J, Tse G, Gin T, Wu WK, Chan MT, Zhang L, 2021 Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance, Huang, D., Wang, X., Liu, Y., Huang, Z., Hu, X., Hu, W., Li, Q., Chan, H., Zou, Y., Ho, I.H. and Wang, Y, 2021 Direct Measurement of B Lymphocyte Gene Expression Biomarkers in Peripheral Blood Transcriptomics Enables Early Prediction of Vaccine Seroconversion, Huang, D., Liu, A.Y., Leung, K.S. and Tang, N.L, 2021 Peripheral Blood T Cell Gene Expression Responses to Exercise and HMB in Sarcopenia, Ma SL, Wu J, Zhu L, Chan RS, Wang X, Huang D, Tang NL, Woo J, 2021 Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase, Li, Q., Hu, W., Liu, W.X., Zhao, L.Y., Huang, D., Liu, X.D., Chan, H., Zhang, Y., Zeng, J.D., Coker, O.O. and Kang, W, 2020 Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets, Lee, K.Y., Leung, K.S., Ma, S.L., So, H.C., Huang, D., Tang, N.L.S. and Wong, M.H, 2020 Ambient Temperature is A Strong Selective Factor Influencing Human Development and Immunity, Ji, L., Wu, D., Xie, H., Yao, B., Chen, Y., Irwin, D.M., Huang, D., Xu, J., Tang, N.L. and Zhang, Y, 2020 Reference intervals of spot urine copper excretion in preschool children and potential application in pre-symptomatic screening of Wilson disease, Tang, N.L.S., Hui, J., Huang, D., Tang, M.F., Wang, X., Wu, J., Chan, I.H. and Leung, T.F, 2020 Genetic susceptibility to Tuberculosis: Interaction between HLA-DQA1 and age of onset, Tang NL, Wang X, Chang KC, Chan CY, Szeto NW, Huang D, Wu J, Lui GC, Leung CC, Hui M, 2019 Deciphering global signal features of high-throughput array data from cancers, Wu D, Kang J, Huang Y, Li X, Wang X, Huang D, Wang Y, Li B, Hao D, Gu Q, Tang N, 2014

Areas of Focus

Genomic Evolution
Tumor Metabolism
Transcriptional Regulation Mechanisms

Publications

METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy, Pan Y, Chen H, Zhang X, Liu W, Ding Y, Huang D, Zhai J, Wei W, Wen J, Chen D, Zhou Y, Liang C, Wong N, Man K, Cheung AH, Wong CC, Yu J, 2023
Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice, Li Q, Chan H, Liu WX, Liu CA, Zhou Y, Huang D, ... & Yu J, 2023
Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer, Bao Y, Zhai J, Chen H, Wong C, Liang C, Ding Y, Huang D, ... & Yu, J, 2023
METTL3 inhibits anti-tumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer, Chen, H., Pan, Y., Zhou, Q., Liang, C., Wong, C. C., Zhou, Y.,Huang, D. ... & Yu, J, 2022
Nonsense-Mediated Decay Targeted RNA (ntRNA): Proposal of a ntRNA-miRNA-lncRNA Triple Regulatory Network Usable as Biomarker of Prognostic Risk in Patients with Kidney Cancer, Zhou Z, Hu F, Huang D, Chi Q, Tang NLS, 2022
3′ untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance, Huang, D.*, Wang, X.*., Huang, Z., Liu, Y., Liu, X., Gin, T., ... & Wu, W. K. K, 2022
Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution, Wang, X., Hu, W., Li, X., Huang, D., Li, Q., Chan, H., Zeng, J., Xie, C., Chen, H., Liu, X. and Gin, T, 2022
Stress Hyperglycemia Is Associated With an Increased Risk of Subsequent Development of Diabetes Among Bacteremic and Nonbacteremic Patients, Wang, X., Cheng, F.T., Lam, T.Y., Liu, Y., Huang, D., Liu, X., Chen, H., Zhang, L., Ali, Y., Wang, M.H. and Yu, J, 2022
Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients, Liu Y, Ling L, Wong SH, Wang MH, Fitzgerald JR, Zou X, Fang S, Liu X, Wang X, Hu W, Chan H, Wang Y, Huang D, Li Q, Wong WT, Choi G, Zou H, Hui DS, Yu J, Tse G, Gin T, Wu WK, Chan MT, Zhang L, 2021
Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance, Huang, D*., Wang, X*., Liu, Y., Huang, Z., Hu, X., Hu, W., Li, Q., Chan, H., Zou, Y., Ho, I.H. and Wang, Y, 2021
Direct Measurement of B Lymphocyte Gene Expression Biomarkers in Peripheral Blood Transcriptomics Enables Early Prediction of Vaccine Seroconversion, Huang, D., Liu, A.Y., Leung, K.S. and Tang, N.L, 2021
Peripheral Blood T Cell Gene Expression Responses to Exercise and HMB in Sarcopenia, Ma SL, Wu J, Zhu L, Chan RS, Wang X, Huang D, Tang NL, Woo J, 2021
Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase, Li, Q., Hu, W., Liu, W.X., Zhao, L.Y., Huang, D., Liu, X.D., Chan, H., Zhang, Y., Zeng, J.D., Coker, O.O. and Kang, W, 2020
Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets, Lee, K.Y., Leung, K.S., Ma, S.L., So, H.C., Huang, D., Tang, N.L.S. and Wong, M.H, 2020
Ambient Temperature is A Strong Selective Factor Influencing Human Development and Immunity, Ji, L., Wu, D., Xie, H., Yao, B., Chen, Y., Irwin, D.M., Huang, D., Xu, J., Tang, N.L. and Zhang, Y, 2020
Reference intervals of spot urine copper excretion in preschool children and potential application in pre-symptomatic screening of Wilson disease, Tang, N.L.S., Hui, J., Huang, D., Tang, M.F., Wang, X., Wu, J., Chan, I.H. and Leung, T.F, 2020
Genetic susceptibility to Tuberculosis: Interaction between HLA-DQA1 and age of onset, Tang NL, Wang X, Chang KC, Chan CY, Szeto NW, Huang D, Wu J, Lui GC, Leung CC, Hui M, 2019
Deciphering global signal features of high-throughput array data from cancers, Wu D, Kang J, Huang Y, Li X, Wang X, Huang D, Wang Y, Li B, Hao D, Gu Q, Tang N, 2014

Genomics Evolution Transcription Regulation Tumor Metabolism Oncology Bioinformatics Data Analysis Molecular Biology

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