Professor | Chao Liang | Asia Growth Partners

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Name	Chao Liang
Contact Information	liangc@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Chao Liang

Contact Information

liangc@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2013-2016 PhD: Hong Kong Baptist University 2010-2013 Master of Science: Anhui Medical University - Military Medical Science Academy 2006-2010 Bachelor of Science: Shandong First Medical University
Work Experience	2020-present, Associate Professor, Southern University of Science and Technology 2018-2020, Research Assistant Professor, Hong Kong Baptist University 2016-2018, Postdoctoral Fellow, Hong Kong Baptist University
Awards	2020: Shenzhen Overseas High-level Talent 2019: National Outstanding Youth

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2013-2016 PhD: Hong Kong Baptist University
2010-2013 Master of Science: Anhui Medical University - Military Medical Science Academy
2006-2010 Bachelor of Science: Shandong First Medical University

Work Experience

2020-present, Associate Professor, Southern University of Science and Technology
2018-2020, Research Assistant Professor, Hong Kong Baptist University
2016-2018, Postdoctoral Fellow, Hong Kong Baptist University

Awards

2020: Shenzhen Overseas High-level Talent
2019: National Outstanding Youth

Areas of Focus	Bone and joint related diseases and tumor mechanisms, translational medicine, and precision medicine
Publications	Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis, Chao Liang et al., 2024 CRISPRa engineered Elite macrophages enable adoptive cell therapy for rheumatoid arthritis, Chao Liang et al., 2024 Repurposing AS1411 for constructing ANM-PROTACs, Chao Liang et al., 2024 Bone disease imaging through the near-infrared-II window, Chao Liang et al., 2023 Targeted protein degradation in cancers: Orthodox PROTACs and beyond, Chao Liang et al., 2023 Targeted Delivery of Chemotherapeutic Agents for Osteosarcoma Treatment, Chao Liang et al., 2022 Therapeutic Effects of (5R)-5-Hydroxytriptolide on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via lncRNA WAKMAR2/miR-4478/E2F1/p53 Axis, Chao Liang et al., 2021 Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli, Chao Liang et al., 2020 Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy, Chao Liang et al., 2015 Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis, Chao Liang et al., 2018 HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis, Chao Liang et al., 2019 Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma, Chao Liang et al., 2017 A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer, Chao Liang et al., 2017 A newly identified lncRNA MAR1 acts as a miR-487b sponge to promote skeletal muscle differentiation and regeneration, Chao Liang et al., 2018 Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis, Chao Liang et al., 2019 Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging, Chao Liang et al., 2017 Long Noncoding RNA lncMUMA Reverses Established Skeletal Muscle Atrophy following Mechanical Unloading, Chao Liang et al., 2018 TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis, Chao Liang et al., 2017 PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs, Chao Liang et al., 2017 Comparison of the methods for generating single-stranded DNA in SELEX, Chao Liang et al., 2015 Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins, Chao Liang et al., 2013

Areas of Focus

Bone and joint related diseases and tumor mechanisms, translational medicine, and precision medicine

Publications

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis, Chao Liang et al., 2024
CRISPRa engineered Elite macrophages enable adoptive cell therapy for rheumatoid arthritis, Chao Liang et al., 2024
Repurposing AS1411 for constructing ANM-PROTACs, Chao Liang et al., 2024
Bone disease imaging through the near-infrared-II window, Chao Liang et al., 2023
Targeted protein degradation in cancers: Orthodox PROTACs and beyond, Chao Liang et al., 2023
Targeted Delivery of Chemotherapeutic Agents for Osteosarcoma Treatment, Chao Liang et al., 2022
Therapeutic Effects of (5R)-5-Hydroxytriptolide on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via lncRNA WAKMAR2/miR-4478/E2F1/p53 Axis, Chao Liang et al., 2021
Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli, Chao Liang et al., 2020
Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy, Chao Liang et al., 2015
Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis, Chao Liang et al., 2018
HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis, Chao Liang et al., 2019
Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma, Chao Liang et al., 2017
A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer, Chao Liang et al., 2017
A newly identified lncRNA MAR1 acts as a miR-487b sponge to promote skeletal muscle differentiation and regeneration, Chao Liang et al., 2018
Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis, Chao Liang et al., 2019
Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging, Chao Liang et al., 2017
Long Noncoding RNA lncMUMA Reverses Established Skeletal Muscle Atrophy following Mechanical Unloading, Chao Liang et al., 2018
TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis, Chao Liang et al., 2017
PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs, Chao Liang et al., 2017
Comparison of the methods for generating single-stranded DNA in SELEX, Chao Liang et al., 2015
Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins, Chao Liang et al., 2013

Bone Disease Joint Disease Tumor Mechanisms Translational Medicine Precision Medicine Research Therapy Diagnosis Treatment Medical Science

Shi Jiejun - Tongji University

Bo Tian - Shanghai University

Wang Luyao - Shanghai University

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