Professor | Yan Yan Li | Asia Growth Partners

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Name	Yan Yan Li
Contact Information	liyy6@sustech.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Yan Yan Li

Contact Information

liyy6@sustech.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2009-2012 PhD in Pathogenic Microbiology: University of Maryland 2010-2011 PhD in Biochemistry: Duke University 2007-2009 PhD in Fermentation Engineering: Jiangnan University 2003-2007 Bachelor of Engineering in Bioengineering: Hebei Agricultural University
Work Experience	2022-present - Southern University of Science and Technology, School of Life Sciences, Assistant Professor 2019-2022 - Westlake University, School of Life Sciences, Researcher 2016-2019 - Harvard Medical School, Department of Cell Biology, Postdoctoral Fellow 2012-2016 - Jiangnan University, State Key Laboratory of Food Science and Technology, Associate Professor
Awards	Yong Investigator Award (twice): International Endotoxin Society National Natural Science Foundation of China (Youth, General) Zhejiang Province Outstanding Young Scientist Fund

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2009-2012 PhD in Pathogenic Microbiology: University of Maryland
2010-2011 PhD in Biochemistry: Duke University
2007-2009 PhD in Fermentation Engineering: Jiangnan University
2003-2007 Bachelor of Engineering in Bioengineering: Hebei Agricultural University

Work Experience

2022-present - Southern University of Science and Technology, School of Life Sciences, Assistant Professor
2019-2022 - Westlake University, School of Life Sciences, Researcher
2016-2019 - Harvard Medical School, Department of Cell Biology, Postdoctoral Fellow
2012-2016 - Jiangnan University, State Key Laboratory of Food Science and Technology, Associate Professor

Awards

Yong Investigator Award (twice): International Endotoxin Society
National Natural Science Foundation of China (Youth, General)
Zhejiang Province Outstanding Young Scientist Fund

Areas of Focus	Bacterial toxin molecules and pathogenic mechanisms Multidisciplinary approaches to chemical structure and host pathogenic mechanisms Protein structure and function in toxin synthesis and transport
Publications	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins, Sharma S, Zhou R, Wan L, Feng S, Song K, Xu C, Li Y, Liao M, 2021 Structural mechanism of phospholipids translocation by MlaFEDB complex, Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q, Li Y, 2020 Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter, Zhang Y, Fan Q, Chi X, Zhou Q, Li Y, 2020 High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB2FGC, Thélot F, Orlando BJ, Li Y, Liao M, 2020 Structural basis of lipopolysaccharide extraction by the LptB2FGC complex, Li Y, Orlando B, Liao M, 2019 Structural basis of MsbA-mediated lipopolysaccharide transport, Mi W, Li Y, Yoon SH, Ernst RK, Walz T, Liao M, 2017 LPS remodeling is an evolved survival strategy for bacteria, Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK, 2012 Structure and transport mechanism of the human cholesterol transporter ABCG1, Xu D, Li Y, Yang F, Sun C, Pan J, Wang L, Chen Z, Fang S, Yao X, Hou W, Zhou C, Chen Y, 2022 Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin, Zhou Y, Li D, Luo J, ChenA, Li X, Pan Z, Wan L, He L, Li D, Li Y, Dong M, Tao L, 2021

Areas of Focus

Bacterial toxin molecules and pathogenic mechanisms
Multidisciplinary approaches to chemical structure and host pathogenic mechanisms
Protein structure and function in toxin synthesis and transport

Publications

Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins, Sharma S, Zhou R, Wan L, Feng S, Song K, Xu C, Li Y*, Liao M*, 2021
Structural mechanism of phospholipids translocation by MlaFEDB complex, Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q*, Li Y*, 2020
Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter, Zhang Y, Fan Q, Chi X, Zhou Q*, Li Y*, 2020
High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB2FGC, Thélot F, Orlando BJ, Li Y*, Liao M*, 2020
Structural basis of lipopolysaccharide extraction by the LptB2FGC complex, Li Y, Orlando B, Liao M, 2019
Structural basis of MsbA-mediated lipopolysaccharide transport, Mi W, Li Y, Yoon SH, Ernst RK, Walz T, Liao M, 2017
LPS remodeling is an evolved survival strategy for bacteria, Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK*, 2012
Structure and transport mechanism of the human cholesterol transporter ABCG1, Xu D, Li Y, Yang F, Sun C, Pan J, Wang L, Chen Z, Fang S, Yao X, Hou W, Zhou C, Chen Y, 2022
Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin, Zhou Y, Li D, Luo J, ChenA, Li X, Pan Z, Wan L, He L, Li D, Li Y, Dong M, Tao L*, 2021

Toxins Pathogens Chemical Structure Host Mechanisms Protein Structure Transport Proteins Antimicrobial Drugs Vaccine Adjuvants Biochemistry Cell Immunology

Shui Wang - Shanghai Normal University

Weiman Xing - Shanghai Normal University

Fang Yu - Shanghai Normal University

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