Professor | Fengfeng Niu | Asia Growth Partners

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Name	Fengfeng Niu
Contact Information	niuff@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Fengfeng Niu

Contact Information

niuff@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2009 - 2015 PhD in Biochemistry and Molecular Biology: Institute of Biophysics, Chinese Academy of Sciences 2005 - 2009 Bachelor in Life Sciences: Nankai University
Work Experience	2023 - Present, Southern University of Science and Technology, School of Life Sciences, Associate Research Professor 2019 - 2023, Southern University of Science and Technology, School of Life Sciences / Institute for Frontier and Interdisciplinary Science, Research Assistant Professor 2016 - 2019, Southern University of Science and Technology, Department of Biology, Postdoctoral Researcher

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2009 - 2015 PhD in Biochemistry and Molecular Biology: Institute of Biophysics, Chinese Academy of Sciences
2005 - 2009 Bachelor in Life Sciences: Nankai University

Work Experience

2023 - Present, Southern University of Science and Technology, School of Life Sciences, Associate Research Professor
2019 - 2023, Southern University of Science and Technology, School of Life Sciences / Institute for Frontier and Interdisciplinary Science, Research Assistant Professor
2016 - 2019, Southern University of Science and Technology, Department of Biology, Postdoctoral Researcher

Areas of Focus	Structural Biology Intracellular Material Transport
Publications	Autoinhibition and activation of myosin VI revealed by its cryo-EM structure, Niu, F., Li, L., Wang, L., Xiao, J, Xu, S., Liu, Y., Lin, L., Yu, C.#, Wei, Z.#, 2024 Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode, Jia, X.; Lin, L.; Xu, S.; Li, L.; Wei, Z.; Yu, C.#; Niu, F.#, 2023 Autoinhibition and Activation Mechanisms Revealed by the Triangular-shaped Structure of Myosin Va, Niu, F.#, Liu, Y., Sun, K., Xu, S., Dong, J., Yu, C., Yan, K., Wei, Z#, 2022 Cargo Recognition Mechanisms of Yeast Myo2 Revealed by AlphaFold2-Powered Protein Complex Prediction, Liu Y, Li L, Yu C, Zeng F, Niu F#, Wei Z#, 2022 Oligomerized liprin-α promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins, Liang, M., Jin, G., Xie, X., Zhang, W., Li, K., Niu, F., Yu, C., Wei, Z., 2021 F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis, Niu, F., Sun, K., Wei, W., Yu, C., Wei, Z., 2020 Structural basis for DNA recognition by STAT6, Li, J. , Rodriguez, J. P. , Niu, F., Pu, M., Wang, J., Hung, L. W., … & Ouyang, S., 2016 All Ca 2+-binding loops of light-sensitive ctenophore photoprotein berovin bind magnesium ions: The spatial structure of Mg2+-loaded apo-berovin, Burakova, L. P., Natashin, P. V., Malikova, N. P., Niu, F., Pu, M., Vysotski, E. S., & Liu, Z. J., 2016 Mechanism of the Rpn13-induced activation of Uch37, Jiao, L., Ouyang, S., Shaw, N., Song, G., Feng, Y., Niu, F., … & Liu, Z. J., 2014 Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin, Gu, J., Feng, Y., Feng, X., Sun, C., Lei, L., Ding, W., Niu, F., … & Han, W., 2014 Structure of the Leanyer orthobunyavirus nucleoprotein–RNA complex reveals unique architecture for RNA encapsidation, Niu, F., Shaw, N., Wang, Y. E., Jiao, L., Ding, W., Li, X., … & Liu, Z. J., 2013 Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential, Jiao, L., Ouyang, S., Liang, M., Niu, F., Shaw, N., Wu, W., … & Liu, Z. J., 2013 Structural biology study of human TNF receptor associated factor 4 TRAF domain, Niu, F., Ru, H., Ding, W., Ouyang, S., & Liu, Z. J., 2013 Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding, Ouyang, S., Song, X., Wang, Y., Ru, H., Shaw, N., Jiang, Y., Niu, F., … & Liu, Z. J., 2012

Areas of Focus

Structural Biology
Intracellular Material Transport

Publications

Autoinhibition and activation of myosin VI revealed by its cryo-EM structure, Niu, F.*, Li, L.*, Wang, L., Xiao, J, Xu, S., Liu, Y., Lin, L., Yu, C.#, Wei, Z.#, 2024
Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode, Jia, X.*; Lin, L.*; Xu, S.; Li, L.; Wei, Z.; Yu, C.#; Niu, F.#, 2023
Autoinhibition and Activation Mechanisms Revealed by the Triangular-shaped Structure of Myosin Va, Niu, F.*#, Liu, Y.*, Sun, K.*, Xu, S., Dong, J., Yu, C., Yan, K., Wei, Z#, 2022
Cargo Recognition Mechanisms of Yeast Myo2 Revealed by AlphaFold2-Powered Protein Complex Prediction, Liu Y, Li L, Yu C, Zeng F, Niu F#, Wei Z#, 2022
Oligomerized liprin-α promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins, Liang, M.*, Jin, G.*, Xie, X.*, Zhang, W., Li, K., Niu, F., Yu, C., Wei, Z., 2021
F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis, Niu, F.*, Sun, K.*, Wei, W., Yu, C., Wei, Z., 2020
Structural basis for DNA recognition by STAT6, Li, J. *, Rodriguez, J. P. *, Niu, F., Pu, M., Wang, J., Hung, L. W., … & Ouyang, S., 2016
All Ca 2+-binding loops of light-sensitive ctenophore photoprotein berovin bind magnesium ions: The spatial structure of Mg2+-loaded apo-berovin, Burakova, L. P., Natashin, P. V., Malikova, N. P., Niu, F., Pu, M., Vysotski, E. S., & Liu, Z. J., 2016
Mechanism of the Rpn13-induced activation of Uch37, Jiao, L.*, Ouyang, S.*, Shaw, N., Song, G., Feng, Y., Niu, F., … & Liu, Z. J., 2014
Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin, Gu, J., Feng, Y., Feng, X., Sun, C., Lei, L., Ding, W., Niu, F., … & Han, W., 2014
Structure of the Leanyer orthobunyavirus nucleoprotein–RNA complex reveals unique architecture for RNA encapsidation, Niu, F.*, Shaw, N*., Wang, Y. E.*, Jiao, L.*, Ding, W., Li, X., … & Liu, Z. J., 2013
Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential, Jiao, L.*, Ouyang, S.*, Liang, M.*, Niu, F.*, Shaw, N., Wu, W., … & Liu, Z. J., 2013
Structural biology study of human TNF receptor associated factor 4 TRAF domain, Niu, F., Ru, H., Ding, W., Ouyang, S., & Liu, Z. J., 2013
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding, Ouyang, S.*, Song, X.*, Wang, Y.*, Ru, H.*, Shaw, N., Jiang, Y., Niu, F., … & Liu, Z. J., 2012

Protein Structure Molecular Motors Biochemistry Cell Biology Cryo-Em Myosin Cargo Transport Molecular Mechanisms Cellular Processes Pathogen Interaction

Shaojun Dai - Shanghai Normal University

Fang Yu - Shanghai Normal University

Yonglan Cui - Shanghai Normal University

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