Professor | Xiaochen Wang | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Xiaochen Wang
Contact Information	wangxc7@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Xiaochen Wang

Contact Information

wangxc7@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	1994-1999 PhD: Peking University Howard Hughes Medical Institute (HHMI) International Young Scientist Award Selected for the National Thousand Talents Program
Work Experience	2023.07 - Present - Southern University of Science and Technology - Chair Professor 2016.05 - 2023.06 - Institute of Biophysics, Chinese Academy of Sciences - Researcher 2011.07 - 2016.04 - Beijing Institute of Life Sciences - Senior Researcher 2006.05 - 2011.07 - Beijing Institute of Life Sciences - Researcher 1999.09 - 2006.04 - University of Colorado - Postdoctoral Researcher
Awards	2019: Selected for the State Council Special Allowance 2015: Selected for the Ministry of Science and Technology Innovation Talent Promotion Plan 2014: National Thousand Talents Program 2013: Tenth China Young Women Scientist Award 2013: National Outstanding Young Scientist Fund 2012: Howard Hughes Medical Institute (HHMI) International Young Scientist Award 2012: WuXi AppTec Life Science and Chemistry Research Award Scholar

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

1994-1999 PhD: Peking University
Howard Hughes Medical Institute (HHMI) International Young Scientist Award
Selected for the National Thousand Talents Program

Work Experience

2023.07 - Present - Southern University of Science and Technology - Chair Professor
2016.05 - 2023.06 - Institute of Biophysics, Chinese Academy of Sciences - Researcher
2011.07 - 2016.04 - Beijing Institute of Life Sciences - Senior Researcher
2006.05 - 2011.07 - Beijing Institute of Life Sciences - Researcher
1999.09 - 2006.04 - University of Colorado - Postdoctoral Researcher

Awards

2019: Selected for the State Council Special Allowance
2015: Selected for the Ministry of Science and Technology Innovation Talent Promotion Plan
2014: National Thousand Talents Program
2013: Tenth China Young Women Scientist Award
2013: National Outstanding Young Scientist Fund
2012: Howard Hughes Medical Institute (HHMI) International Young Scientist Award
2012: WuXi AppTec Life Science and Chemistry Research Award Scholar

Areas of Focus	Lysosomal research using C. elegans Cell degradation processes mediated by lysosomes
Publications	Lysosomal chloride transporter CLH-6 protects lysosome membrane integrity via cathepsin activation, Zhang Q, Li Y, Jian Y, Li M, Wang X, 2023 Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C.elegans, Sun Y, Li M, Zhao D, Li X, Yang C, Wang X, 2020 An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval development, Miao R, Li M, Zhang Q, Yang C, Wang X, 2020 Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development, Liu Y, Zou W, Yang P, Wang L, Ma Y, Zhang H, Wang X, 2018 GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans, Yin J, Huang Y, Guo P, Hu S, Yoshina S, Xuan N, Gan Q, Mitani S, Yang C, Wang X, 2017 The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity, Li Y, Chen B, Zou W, Wang X, Wu Y, Zhao D, Sun Y, Liu Y, Chen L, Miao L, Yang C, Wang X, 2016 PtdIns(4,5)P2 and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance, Cheng S, Wang K, Zou W, Miao R, Huang Y, Wang H, Wang X, 2015 C. elegans secreted lipid-binding protein NRF-5 mediates PS appearance on phagocytes for cell corpse engulfment, Zhang Y, Wang H, Kage-Nakadai E, Mitani S, Wang X, 2012 LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis, Liu B, Du H, Rutkowski R, Gartner A, Wang X, 2012 Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation, Guo P, Hu T, Zhang J, Jiang S, Wang X, 2010 Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor, Wang X, Li W, Zhao D, Liu B, Shi Y, Chen B, Yang H, Guo P, Geng X, Shang Z, Peden E, Kage-Nakadai E, Mitani S, Xue D, 2010

Areas of Focus

Lysosomal research using C. elegans
Cell degradation processes mediated by lysosomes

Publications

Lysosomal chloride transporter CLH-6 protects lysosome membrane integrity via cathepsin activation, Zhang Q, Li Y, Jian Y, Li M, Wang X, 2023
Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C.elegans, Sun Y, Li M, Zhao D, Li X, Yang C, Wang X, 2020
An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval development, Miao R, Li M, Zhang Q, Yang C, Wang X, 2020
Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development, Liu Y, Zou W, Yang P, Wang L, Ma Y, Zhang H, Wang X, 2018
GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans, Yin J, Huang Y, Guo P, Hu S, Yoshina S, Xuan N, Gan Q, Mitani S, Yang C, Wang X, 2017
The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity, Li Y, Chen B, Zou W, Wang X, Wu Y, Zhao D, Sun Y, Liu Y, Chen L, Miao L, Yang C, Wang X, 2016
PtdIns(4,5)P2 and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance, Cheng S, Wang K, Zou W, Miao R, Huang Y, Wang H, Wang X, 2015
C. elegans secreted lipid-binding protein NRF-5 mediates PS appearance on phagocytes for cell corpse engulfment, Zhang Y, Wang H, Kage-Nakadai E, Mitani S, Wang X, 2012
LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis, Liu B, Du H, Rutkowski R, Gartner A, Wang X, 2012
Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation, Guo P, Hu T, Zhang J, Jiang S, Wang X, 2010
Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor, Wang X, Li W, Zhao D, Liu B, Shi Y, Chen B, Yang H, Guo P, Geng X, Shang Z, Peden E, Kage-Nakadai E, Mitani S, Xue D, 2010

Lysosomes C. Elegans Cell Degradation Apoptotic Cell Clearance Genetics Cell Biology Biochemistry Nanoparticles Physiological Functions Pathological Functions

Shaojun Dai - Shanghai Normal University

Fang Yu - Shanghai Normal University

Yonglan Cui - Shanghai Normal University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us