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Tian Xie
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Lipids
Enzymes
Metabolic Pathways
Cellular Processes
Molecular Structures
Protein Functions
Gene Regulation
Metabolism Disorders
Biomolecular Interactions
Therapeutic Targets
Areas of Focus
- Lipid Metabolism
- Biochemistry
- Structural Biology
Work Experience
- 2019 - Present Southern University of Science and Technology, Department of Biology - Associate Research Professor
- 2017 - 2019 University of Texas Southwestern Medical Center - Postdoctoral Researcher
- 2015 - 2017 MRC Laboratory of Molecular Biology, UK - Postdoctoral Researcher
Academic Background & Achievements
- 2010 - 2015 PhD: Tsinghua University
- 2006 - 2010 Bachelor: University of Science and Technology of China
Publications
- Structure and mechanism of a eukaryotic ceramide synthase complex, Xie T, 2023
- Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis, Xie T, 2023
- Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex, Xie T, 2023
- Cryo-EM structures of the human surfactant lipid transporter ABCA3, Xie T, 2022
- Structural basis of substrate recognition and translocation by human ABCA4, Xie T, 2021
- Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex, Xie T, 2021
Awards
- Shenzhen Overseas High-level Talent
