Professor | Xiaoling Yu | Asia Growth Partners

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Name	Xiaoling Yu
Contact Information	yxl3@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Xiaoling Yu

Contact Information

yxl3@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2005 - 2008 PhD in Cell Biology: Fourth Military Medical University Postdoctoral research at Harvard Medical School Published 17 SCI papers and multiple patents
Work Experience	2023 - Present: Southern University of Science and Technology, Associate Research Professor 2022 - 2023: Shenzhen Bay Laboratory, Associate Researcher 2018 - 2022: Southern University of Science and Technology, Assistant Research Professor 2012 - 2015: Harvard Medical School, Postdoctoral Researcher 2010 - 2017: Fourth Military Medical University, Associate Professor
Awards	2018: Shenzhen High-level Local Leading Talent 2014: First Prize in Scientific Research and Technological Inventions by the Ministry of Education 2008: Young Scholar Award of the Chinese Immunology Society 2007: Outstanding Young Paper Award of the Chinese Society for Cell Biology

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2005 - 2008 PhD in Cell Biology: Fourth Military Medical University
Postdoctoral research at Harvard Medical School
Published 17 SCI papers and multiple patents

Work Experience

2023 - Present: Southern University of Science and Technology, Associate Research Professor
2022 - 2023: Shenzhen Bay Laboratory, Associate Researcher
2018 - 2022: Southern University of Science and Technology, Assistant Research Professor
2012 - 2015: Harvard Medical School, Postdoctoral Researcher
2010 - 2017: Fourth Military Medical University, Associate Professor

Awards

2018: Shenzhen High-level Local Leading Talent
2014: First Prize in Scientific Research and Technological Inventions by the Ministry of Education
2008: Young Scholar Award of the Chinese Immunology Society
2007: Outstanding Young Paper Award of the Chinese Society for Cell Biology

Areas of Focus	Structural studies of biomolecular machines and membrane proteins using cryo-electron microscopy Systemic structural proteomics
Publications	A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis, Guo N, Ye S, Zhang K, Yu X, Cui H, Yang X, Lin P, Lv M, Miao J, Zhang Y, Han Q, Zhang R, Chen Z, Zhu P, 2019 Architecture of the human PI4KIIIα lipid kinase complex, Lees JA, Zhang Y, Oh MS, Schauder CM, Yu X, Baskin JM, Dobbs K, Notarangelo LD, De Camilli P, Walz T, Reinisch KM, 2017 Molecular architecture of the αβ T cell receptor-CD3 complex, Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-Vazquez MA, Yu X, Waghray D, Fischer S, McCluskey J, Rossjohn J, Walz T, Garcia KC, 2014 Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion, Yu XL, Hu T, Du JM, Yang XM, Zhang J, Yang B, Shen X, Zhang Z, Zhong WD, Wen N, Ding JP, Jiang H, Zhu P, Chen ZN, 2008 The glycosylation characteristic of hepatoma-associated antigen HAb18G/CD147 in human hepatoma cells, Yu XL, Jiang JL, Li L, Feng Q, Xu J, Chen ZN, 2006 CD147 reinforces [Ca2+]i oscillations and promotes oncogenic progression in hepatocellular carcinoma, Tang J, Guo YS, Yu XL, Huang W, Zheng M, Zhou YH, Nan G, Wang JC, Yang HJ, Yu JM, Jiang JL, Chen ZN, 2015 Dimerization is essential for HAb18G/CD147 promoting tumor invasion via MAPK pathway, Cui HY, Guo T, Wang SJ, Zhao P, Dong ZS, Zhang Y, Jiang JL, Chen ZN, Yu XL, 2012 CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma, Tang J, Guo YS, Zhang Y, Yu XL, Li L, Huang W, Li Y, Chen B, Jiang JL, Chen ZN, 2012

Areas of Focus

Structural studies of biomolecular machines and membrane proteins using cryo-electron microscopy
Systemic structural proteomics

Publications

A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis, Guo N, Ye S, Zhang K, Yu X, Cui H, Yang X, Lin P, Lv M, Miao J, Zhang Y, Han Q, Zhang R, Chen Z, Zhu P, 2019
Architecture of the human PI4KIIIα lipid kinase complex, Lees JA, Zhang Y, Oh MS, Schauder CM, Yu X, Baskin JM, Dobbs K, Notarangelo LD, De Camilli P, Walz T, Reinisch KM, 2017
Molecular architecture of the αβ T cell receptor-CD3 complex, Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-Vazquez MA, Yu X, Waghray D, Fischer S, McCluskey J, Rossjohn J, Walz T, Garcia KC, 2014
Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion, Yu XL, Hu T, Du JM, Yang XM, Zhang J, Yang B, Shen X, Zhang Z, Zhong WD, Wen N, Ding JP, Jiang H, Zhu P, Chen ZN, 2008
The glycosylation characteristic of hepatoma-associated antigen HAb18G/CD147 in human hepatoma cells, Yu XL, Jiang JL, Li L, Feng Q, Xu J, Chen ZN, 2006
CD147 reinforces [Ca2+]i oscillations and promotes oncogenic progression in hepatocellular carcinoma, Tang J, Guo YS, Yu XL, Huang W, Zheng M, Zhou YH, Nan G, Wang JC, Yang HJ, Yu JM, Jiang JL, Chen ZN, 2015
Dimerization is essential for HAb18G/CD147 promoting tumor invasion via MAPK pathway, Cui HY, Guo T, Wang SJ, Zhao P, Dong ZS, Zhang Y, Jiang JL, Chen ZN, Yu XL, 2012
CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma, Tang J, Guo YS, Zhang Y, Yu XL, Li L, Huang W, Li Y, Chen B, Jiang JL, Chen ZN, 2012

Cryo-Electron Microscopy Biomolecular Machines Membrane Proteins Molecular Mechanisms Structural Biology Proteomics Systemic Studies Protein Structure Biological Research Molecular Biology

Jianhuang Xue - Tongji University

Hua Yang - Tongji University

Chong Wang - Shanghai Normal University

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