Upload Avatar (500 x 500)
Wen Zhou
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Phase Separation
Immune Signaling
Biomolecular Condensates
Pathogens
Stress
Cancer
Nucleic Acids
Dna
Rna
Receptors
Areas of Focus
- Phase separation in immune signaling
- Discovery of new receptors involved in nucleic acid immune response
Work Experience
- 2021.04-Present - Southern University of Science and Technology, Assistant Professor
- 2017.07-2021.03 - Harvard Medical School / Dana-Farber Cancer Institute, Postdoctoral Fellow
Academic Background & Achievements
- 2009-2017 PhD in Developmental Biology: Chinese Academy of Sciences
- 2017 PhD Thesis Award from the Chinese Academy of Sciences
- 2017 President's Award from the Chinese Academy of Sciences
Publications
- Structure of the human cGAS–DNA complex reveals enhanced control of immune surveillance, Zhou W, et al., 2018
- cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing, Zhou W, et al., 2021
- PPR-SMR protein SOT1 has RNA endonuclease activity, Zhou W, et al., 2017
- Analysis of human cGAS activity and structure, Zhou W, et al., 2019
- Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA, Zhou W, et al., 2019
Awards
- 2020 Charles A. King Trust Fellowship Award
- 2019 Benacerraf Postdoctoral Fellowship Award
- 2019 Harvard Chinese Life Sciences Distinguished Research Award
