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Mingjie Zhang
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Neural
Signal Transduction
Protein Complexes
Biochemistry
Structure
Neuronal Polarity
Mechanisms
Generation
Maintenance
Cell Biology
Areas of Focus
- Biochemical and structural basis of important protein complexes in neural signal transduction
- Mechanisms of generation and maintenance of neuronal polarity
Work Experience
- 2020-Present Dean, School of Life Sciences, Southern University of Science and Technology
- 2019-Present Convener, Senior Researcher, Guangdong-Hong Kong-Macao Biomedical Innovation Center, Shenzhen Bay Laboratory
- 2004-2020 Deputy Director, Institute Director, Peking University-Hong Kong University of Science and Technology Medical Center
- 1995-2020 Professor, Senior Researcher, Hong Kong University of Science and Technology
- 1995-2020 Deputy Director, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology
- 1994-1995 Postdoctoral Fellow, Ontario Cancer Institute, Canada
Academic Background & Achievements
- 1984-1988 Bachelor in Chemistry, Fudan University, Shanghai, China
- 1989-1993 PhD in Biochemistry, University of Calgary, Canada
- 1994-1995 Postdoctoral Fellow, Ontario Cancer Institute, University of Toronto, Canada
Publications
- Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission, Zeng, M., Díaz-Alonso, J., Ye, F., Chen, X., Xu, J., Ji, Z., Nicoll, RA., and Zhang, M., 2019
- Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity, Zeng, M., Chen, X., Guan, D., Xu, J., Wu, H., Tong, P., and Zhang, M., 2018
- Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins, Li, J., Zhu, R., Chen, K., Zheng, H., Zhao, H., Yuan, C., Zhang, H., Wang, C., and Zhang, M., 2018
- DISC1 regulates neurogenesis via modulating kinetochore attachment of Ndel1/Nde1 during mitosis, Ye, F., Kang, E., Yu, C., Qian, X., Jacob, F., Yu, C., Song, H., Ming, G., and Zhang, M., 2017
- Phase transition in postsynaptic densities underlies formation of synaptic complexes and synaptic plasticity, Zeng, M. Shang, Y., Araki, Y., Guo, T., Huganir, R. L., and Zhang, M., 2016
Awards
- 2002 Overseas Outstanding Young Scientist Award, National Natural Science Foundation of China
- 2003 Qiushi Outstanding Researcher Award
- 2006 Second Prize, National Natural Science Award (First Completer)
- 2011 Ho Leung Ho Lee Foundation Science and Technology Progress Award
- 2021 Tan Jiazhen Life Science Achievement Award
