Professor | Zhang Li | Asia Growth Partners

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Name	Zhang Li
Contact Information	zhangl3@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Zhang Li

Contact Information

zhangl3@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2004-2008 Bachelor of Science: Sichuan University, Biological Sciences 2008-2013 PhD: Peking Union Medical College and Beijing Institute of Life Sciences, Biochemistry and Molecular Biology
Work Experience	July 2013 - April 2015: Postdoctoral Researcher, Beijing Institute of Life Sciences April 2015 - February 2021: Postdoctoral Researcher, Weill Cornell Medical College, Department of Microbiology and Immunology March 2021 - December 2021: Assistant Professor, Weill Cornell Medical College, Department of Microbiology and Immunology February 2022 - Present: Assistant Professor, Southern University of Science and Technology, School of Life Sciences, Department of Biology
Awards	Cancer Research Institute/Robertson Foundation Fellow (2017): Cancer Research Institute Young Scientist Award (2014): 4th Asia Pacific Protein Association Conference Outstanding Graduate Student (2013, 2012): Peking Union Medical College Wu Rui Scholarship (2012): Wu Rui Foundation Outstanding Graduate Student (2011): Beijing Institute of Life Sciences Comprehensive Scholarship (2007): Sichuan University Huang Qianheng Scholarship (2006): Sichuan University National Scholarship (2005): Sichuan University

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2004-2008 Bachelor of Science: Sichuan University, Biological Sciences
2008-2013 PhD: Peking Union Medical College and Beijing Institute of Life Sciences, Biochemistry and Molecular Biology

Work Experience

July 2013 - April 2015: Postdoctoral Researcher, Beijing Institute of Life Sciences
April 2015 - February 2021: Postdoctoral Researcher, Weill Cornell Medical College, Department of Microbiology and Immunology
March 2021 - December 2021: Assistant Professor, Weill Cornell Medical College, Department of Microbiology and Immunology
February 2022 - Present: Assistant Professor, Southern University of Science and Technology, School of Life Sciences, Department of Biology

Awards

Cancer Research Institute/Robertson Foundation Fellow (2017): Cancer Research Institute
Young Scientist Award (2014): 4th Asia Pacific Protein Association Conference
Outstanding Graduate Student (2013, 2012): Peking Union Medical College
Wu Rui Scholarship (2012): Wu Rui Foundation
Outstanding Graduate Student (2011): Beijing Institute of Life Sciences
Comprehensive Scholarship (2007): Sichuan University
Huang Qianheng Scholarship (2006): Sichuan University
National Scholarship (2005): Sichuan University

Areas of Focus	Mycobacterium tuberculosis and host interaction Macrophage death mechanisms induced by Mycobacterium tuberculosis infection Role of Type I interferon in tuberculosis Host-directed therapies for pulmonary tuberculosis
Publications	Type I Interferon Signaling Mediates Mycobacterium tuberculosis-Induced Macrophage Death, Zhang L, Jiang X, Pfau D, Ling Y, Nathan CF, 2021 Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway, Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ, Shao F, 2014 Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains, Li S, Zhang L, Yao Q, Li L, Dong N, Rong J, Gao W, Ding X, Sun L, Chen X, Chen S, Shao F, 2013 Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation, Zhang L, Ding X, Cui J, Xu H, Chen J, Gong YN, Hu L, Zhou Y, Ge J, Lu Q, Liu L, Chen S, Shao F, 2012 Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB, Bryk R, Mundhra S, Jiang X, Wood M, Pfau D, Weber E, Park S, Zhang L, Wilson C, Van der Westhuyzen R, Street L, Chibale K, Zimmerman M, Dartois V, Pastore N, Ballabio A, Hawryluk N, Canan S, Khetani V, Camardo J, Nathan C, 2020 Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway, Litvak Y, Sharon S, Hyams M, Zhang L, Kobi S, Katsowich N, Dishon S, Nussbaum G, Dong N, Shao F, Rosenshine I, 2017 Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome, Xu H, Yang J, Gao W, Li L, Li P, Zhang L, Gong YN, Peng X, Xi J, Chen S, Wang F, Shao F, 2014 The Plant-Specific Actin Binding Protein SCAB1 Stabilizes Actin Filaments and Regulates Stomatal Movement in Arabidopsis, Zhao Y, Zhao S, Mao T, Qu X, Cao W, Zhang L, Zhang W, He L, Li S, Ren S, Zhao J, Zhu G, Huang S, Ye K, Yuan M, Guo Y, 2011

Areas of Focus

Mycobacterium tuberculosis and host interaction
Macrophage death mechanisms induced by Mycobacterium tuberculosis infection
Role of Type I interferon in tuberculosis
Host-directed therapies for pulmonary tuberculosis

Publications

Type I Interferon Signaling Mediates Mycobacterium tuberculosis-Induced Macrophage Death, Zhang L, Jiang X, Pfau D, Ling Y, Nathan CF, 2021
Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway, Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ, Shao F, 2014
Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains, Li S, Zhang L, Yao Q, Li L, Dong N, Rong J, Gao W, Ding X, Sun L, Chen X, Chen S, Shao F, 2013
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation, Zhang L, Ding X, Cui J, Xu H, Chen J, Gong YN, Hu L, Zhou Y, Ge J, Lu Q, Liu L, Chen S, Shao F, 2012
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB, Bryk R, Mundhra S, Jiang X, Wood M, Pfau D, Weber E, Park S, Zhang L, Wilson C, Van der Westhuyzen R, Street L, Chibale K, Zimmerman M, Dartois V, Pastore N, Ballabio A, Hawryluk N, Canan S, Khetani V, Camardo J, Nathan C, 2020
Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway, Litvak Y, Sharon S, Hyams M, Zhang L, Kobi S, Katsowich N, Dishon S, Nussbaum G, Dong N, Shao F, Rosenshine I, 2017
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome, Xu H, Yang J, Gao W, Li L, Li P, Zhang L, Gong YN, Peng X, Xi J, Chen S, Wang F, Shao F, 2014
The Plant-Specific Actin Binding Protein SCAB1 Stabilizes Actin Filaments and Regulates Stomatal Movement in Arabidopsis, Zhao Y, Zhao S, Mao T, Qu X, Cao W, Zhang L, Zhang W, He L, Li S, Ren S, Zhao J, Zhu G, Huang S, Ye K, Yuan M, Guo Y, 2011

Mycobacterium Tuberculosis Host Interaction Macrophage Death Infection Mechanisms Type I Interferon Tuberculosis Host-Directed Therapies Pulmonary Tuberculosis Immune Response Pathogen-Host Dynamics

Xinhua Huang - University of Chinese Academy of Sciences

Lu Meng - University of Chinese Academy of Sciences

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