Professor | Wei Man Xing | Asia Growth Partners

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Name	Wei Man Xing
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Wei Man Xing

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Normal University
Faculty	Life Sciences
Academic Background & Achievements	2000-2007 PhD: Institute of Biophysics, Chinese Academy of Sciences & Beijing Institute of Life Sciences 1996-2000 Bachelor: Department of Biochemistry, Nankai University
Work Experience	2019-Present - Shanghai Normal University - Researcher / Doctoral Supervisor 2014-2019 - Shanghai Center for Plant Stress Biology - Researcher / Doctoral Supervisor 2008-2014 - University of Washington & Howard Hughes Medical Institute - Postdoctoral Researcher
Awards	2015: Youth Thousand Talents Plan

University/Lab Affiliation and Title

Shanghai Normal University

Faculty

Life Sciences

Academic Background & Achievements

2000-2007 PhD: Institute of Biophysics, Chinese Academy of Sciences & Beijing Institute of Life Sciences
1996-2000 Bachelor: Department of Biochemistry, Nankai University

Work Experience

2019-Present - Shanghai Normal University - Researcher / Doctoral Supervisor
2014-2019 - Shanghai Center for Plant Stress Biology - Researcher / Doctoral Supervisor
2008-2014 - University of Washington & Howard Hughes Medical Institute - Postdoctoral Researcher

Awards

2015: Youth Thousand Talents Plan

Areas of Focus	Plant pathogen pathogenic mechanisms Plant disease resistance mechanisms Perception mechanisms of bioactive small molecules
Publications	Mechanism of Phosphate Sensing and Signaling Revealed by Rice SPX1-PHR2 Complex Structure, Zhou J, Hu Q, Xiao X, Yao D, Ge S, Ye J, Li H, Cai R, Liu R, Meng F, Wang C, Zhu J-K, Lei M, Xing W, 2021 Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection, Lin Y, Hu Q, Zhou J, Yin W, Yao D, Shao Y, Zhao Y, Guo B, Xia Y, Chen Q, Wang Y, Ye W, Xie Q, Tyler BM, Xing W, Wang Y, 2021 Expression, purification and crystallization of the N-terminal Solanaceae domain of the Sw-5b NLR immune receptor, Li J, Xin J, Zhao X, Zhao Y, Wang T, Xing W, Tao X, 2021 The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function, Wang F, Fang J, Guan K, Luo S, Dogra V, Li B, Ma D, Zhao X, Lee KP, Sun P, Xin J, Liu T, Xing W, Kim C, 2020 PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex, Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L, Li J, 2019 Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection, Guo B, Wang H, Yang B, Jiang W, Jing M, Li H, Xia Y, Xu Y, Hu Q, Wang F, Yu F, Wang Y, Ye W, Dong S, Xing W, Wang Y, 2019 Glycolysis regulates pollen tube polarity via Rho GTPase signaling, Chen W, Gong P, Guo J, Li H, Li R, Xing W, Yang Z, Guan Y, 2018 A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi, Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhang H, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R, 2018 An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity, Huang J, Gu L, Zhang Y, Yan T, Kong G, Kong L, Guo B, Qiu M, Wang Y, Jing M, Xing W, Ye W, Wu Z, Zhang Z, Zheng X, Gijzen M, Wang Y, Dong S, 2017 Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase, Nangle S, Xing W, Zheng N, 2013 SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket, Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N, 2013 The structural basis for activation of plant immunity by bacterial effector protein AvrPto, Xing W, Zou Y, Liu Q, Liu J, Luo X, Huang Q, Chen S, Zhu L, Bi R, Hao Q, Wu JW, Zhou JM, Chai J, 2007 Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases, Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM, 2008 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii, Liu HL, Zhou HN, Xing WM, Zhao JF, Li SX, Huang JF, Bi RC, 2004

Areas of Focus

Plant pathogen pathogenic mechanisms
Plant disease resistance mechanisms
Perception mechanisms of bioactive small molecules

Publications

Mechanism of Phosphate Sensing and Signaling Revealed by Rice SPX1-PHR2 Complex Structure, Zhou J, Hu Q, Xiao X, Yao D, Ge S, Ye J, Li H, Cai R, Liu R, Meng F, Wang C, Zhu J-K, Lei M, Xing W, 2021
Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection, Lin Y, Hu Q, Zhou J, Yin W, Yao D, Shao Y, Zhao Y, Guo B, Xia Y, Chen Q, Wang Y, Ye W, Xie Q, Tyler BM, Xing W, Wang Y, 2021
Expression, purification and crystallization of the N-terminal Solanaceae domain of the Sw-5b NLR immune receptor, Li J, Xin J, Zhao X, Zhao Y, Wang T, Xing W, Tao X, 2021
The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function, Wang F, Fang J, Guan K, Luo S, Dogra V, Li B, Ma D, Zhao X, Lee KP, Sun P, Xin J, Liu T, Xing W, Kim C, 2020
PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex, Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L, Li J, 2019
Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection, Guo B, Wang H, Yang B, Jiang W, Jing M, Li H, Xia Y, Xu Y, Hu Q, Wang F, Yu F, Wang Y, Ye W, Dong S, Xing W, Wang Y, 2019
Glycolysis regulates pollen tube polarity via Rho GTPase signaling, Chen W, Gong P, Guo J, Li H, Li R, Xing W, Yang Z, Guan Y, 2018
A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi, Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhang H, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R, 2018
An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity, Huang J, Gu L, Zhang Y, Yan T, Kong G, Kong L, Guo B, Qiu M, Wang Y, Jing M, Xing W, Ye W, Wu Z, Zhang Z, Zheng X, Gijzen M, Wang Y, Dong S, 2017
Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase, Nangle S, Xing W, Zheng N, 2013
SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket, Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N, 2013
The structural basis for activation of plant immunity by bacterial effector protein AvrPto, Xing W, Zou Y, Liu Q, Liu J, Luo X, Huang Q, Chen S, Zhu L, Bi R, Hao Q, Wu JW, Zhou JM, Chai J, 2007
Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases, Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM, 2008
2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii, Liu HL, Zhou HN, Xing WM, Zhao JF, Li SX, Huang JF, Bi RC, 2004

Pathogens Plant Biology Molecular Biology Biochemistry Disease Resistance Small Molecules Perception Signaling Pathways Molecular Mechanisms Plant Health

Yanfang Wang - Tongji University

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