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Wei Man Xing
Life Science
Shanghai Normal University
Shanghai
Language: Chinese, English
Pathogens
Plant Biology
Molecular Biology
Biochemistry
Disease Resistance
Small Molecules
Perception
Signaling Pathways
Molecular Mechanisms
Plant Health
Areas of Focus
- Plant pathogen pathogenic mechanisms
- Plant disease resistance mechanisms
- Perception mechanisms of bioactive small molecules
Work Experience
- 2019-Present - Shanghai Normal University - Researcher / Doctoral Supervisor
- 2014-2019 - Shanghai Center for Plant Stress Biology - Researcher / Doctoral Supervisor
- 2008-2014 - University of Washington & Howard Hughes Medical Institute - Postdoctoral Researcher
Academic Background & Achievements
- 2000-2007 PhD: Institute of Biophysics, Chinese Academy of Sciences & Beijing Institute of Life Sciences
- 1996-2000 Bachelor: Department of Biochemistry, Nankai University
Publications
- Mechanism of Phosphate Sensing and Signaling Revealed by Rice SPX1-PHR2 Complex Structure, Zhou J, Hu Q, Xiao X, Yao D, Ge S, Ye J, Li H, Cai R, Liu R, Meng F, Wang C, Zhu J-K, Lei M, Xing W, 2021
- Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection, Lin Y, Hu Q, Zhou J, Yin W, Yao D, Shao Y, Zhao Y, Guo B, Xia Y, Chen Q, Wang Y, Ye W, Xie Q, Tyler BM, Xing W, Wang Y, 2021
- Expression, purification and crystallization of the N-terminal Solanaceae domain of the Sw-5b NLR immune receptor, Li J, Xin J, Zhao X, Zhao Y, Wang T, Xing W, Tao X, 2021
- The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function, Wang F, Fang J, Guan K, Luo S, Dogra V, Li B, Ma D, Zhao X, Lee KP, Sun P, Xin J, Liu T, Xing W, Kim C, 2020
- PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex, Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L, Li J, 2019
- Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection, Guo B, Wang H, Yang B, Jiang W, Jing M, Li H, Xia Y, Xu Y, Hu Q, Wang F, Yu F, Wang Y, Ye W, Dong S, Xing W, Wang Y, 2019
- Glycolysis regulates pollen tube polarity via Rho GTPase signaling, Chen W, Gong P, Guo J, Li H, Li R, Xing W, Yang Z, Guan Y, 2018
- A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi, Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhang H, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R, 2018
- An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity, Huang J, Gu L, Zhang Y, Yan T, Kong G, Kong L, Guo B, Qiu M, Wang Y, Jing M, Xing W, Ye W, Wu Z, Zhang Z, Zheng X, Gijzen M, Wang Y, Dong S, 2017
- Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase, Nangle S, Xing W, Zheng N, 2013
- SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket, Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N, 2013
- The structural basis for activation of plant immunity by bacterial effector protein AvrPto, Xing W, Zou Y, Liu Q, Liu J, Luo X, Huang Q, Chen S, Zhu L, Bi R, Hao Q, Wu JW, Zhou JM, Chai J, 2007
- Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases, Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM, 2008
- 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii, Liu HL, Zhou HN, Xing WM, Zhao JF, Li SX, Huang JF, Bi RC, 2004
Awards
- 2015: Youth Thousand Talents Plan
