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Jiwen Li
jiwenster@gmail.com
English, Chinese
Shanghai
East China Normal University
Life Sciences
  • 1986-09 to 1990-06 Bachelor of Science in Biochemistry: Fudan University
  • 1995-09 to 1997-05 Master of Science in Biomedical Science: Hood College, Supervisor: Dr. Yun-Bo Shi
  • 1997/8-2007/5 - Baylor College of Medicine, Department of Molecular and Cellular Biology, Senior Research Assistant
  • 2007/9 - Present - East China Normal University, School of Life Sciences, Senior Engineer
Regulation of chromatin structure and function by DNA methylation, histone modification, and nucleosome remodeling
Gene expression regulation mechanisms using nuclear hormone receptors as a model
Molecular mechanisms of transcription suppression by SUMO modification and the role and mechanism of SUMO-bound nucleosomes in transcription regulation
  • SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1, Zhang, Huifang; Gao, Qinqin; Tan, Shuo; You, Jia; Lyu, Cong; Zhang, Yunpeng; Han, Mengmeng; Chen, Zhaosu; Li, Jialun; Wang, Hailin; Liao, Lujian; Qin, Jun; Li, Jiwen*; Wong, Jiemin*, 2019
  • SUMOylation down-regulates rDNA transcription by repressing expression of upstream-binding factor and proto-oncogene c-Myc, Peng, Yu; Wang, Zhenxing; Wang, Zhiqiang; Yu, Fang; Li, Jiwen*; Wong, Jiemin*, 2019
  • Activated MEK/ERK Pathway Drives Widespread and Coordinated Overexpression of UHRF1 and DNMT1 in Cancer cells, Li, Jialun; Wang, Ruiping; Hu, Xueli; Gao, Yingying; Wang, Zhen; Li, Jiwen*; Wong, Jiemin*, 2019
  • SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation, Yu, Fang; Shi, Guang; Cheng, Shimeng; Chen, Jiwei; Wu, Shwu Yuan; Wang, Zhiqiang; Xia, Nansong; Zhai, Yunhao; Wang, Zhenxing; Peng, Yu; Wang, Dong; Du, James X; Liao, Lujian; Duan, Sheng Zhong; Shi, Tieliu; Cheng, Jinke; Chiang, Cheng Ming; Li, Jiwen*; Wong, Jiemin*, 2018
  • MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300, Liu Xiaoguang; Wei Wei; Liu Yuting; Yang Xueli; Wu Jian; Zhang Yang; Zhang Qiao; Shi Tieliu; Du James X; Zhao Yingming; Lei Ming; Zhou Jin Qiu; Li Jiwen*; Wong Jiemin*, 2017
Chromatin Dna Methylation Histone Modification Nucleosome Remodeling Gene Expression Nuclear Hormone Receptors Transcription Suppression Sumo Modification Sumo-Bound Nucleosomes Transcription Regulation

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