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Xiongwen Cao
Life Science
East China Normal University
Shanghai
Language: Chinese, English
Genomics
Proteomics
Mass Spectrometry
Bioinformatics
Cancer
Biomarkers
Drug Targets
Cell Communication
Mitochondria
Autophagy
Areas of Focus
- Unannotated microproteins in human genome
- Proteomics methods development
- Cancer biomarkers and drug targets
- Cell-cell communication pathways
- Mitochondrial autophagy
Work Experience
- 2023.1 - Present: Researcher, East China Normal University
- 2019.2 - 2022.12: Postdoctoral Researcher, Department of Chemistry, Yale University
- 2015.12 - 2019.1: Postdoctoral Researcher, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences
Academic Background & Achievements
- 2005.9 - 2009.6: Bachelor in Biotechnology, Huazhong University of Science and Technology
- 2009.9 - 2015.12: PhD in Biochemistry and Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Publications
- Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5, Xiongwen Cao, Sarah A. Slavoff, 2023
- Chemical labeling and proteomics for characterization of unannotated small and alternative open reading frame-encoded polypeptides, Xiongwen Cao, Sarah A. Slavoff, 2023
- BONCAT-based Profiling of Nascent Small and Alternative Open Reading Frame-encoded Proteins, Xiongwen Cao, Sarah A. Slavoff, 2023
- Nascent alt-protein chemoproteomics reveals a pre-60S assembly checkpoint inhibitor, Xiongwen Cao, Sarah A. Slavoff, 2022
- Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID, Xiongwen Cao, Sarah A. Slavoff, 2022
- Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24, Xiongwen Cao, Sarah A. Slavoff, 2021
- Comparative Proteomic Profiling of Unannotated Microproteins and Alternative Proteins in Human Cell Lines, Xiongwen Cao, Sarah A. Slavoff, 2020
- Non-AUG start codons: Expanding and regulating the small and alternative ORFeome, Xiongwen Cao, Sarah A. Slavoff, 2020
- Histone H4K20 Demethylation by Two hHR23 Proteins, Xiongwen Cao, Sarah A. Slavoff, 2020
- Cis-existence of H3K27me3 and H3K36me2 in mouse embryonic stem cells revealed by specific ions of isobaric modification chromatogram, Xiongwen Cao, Charlie Degui Chen, 2015
- Yeast Hmt1 catalyses asymmetric dimethylation of histone H3 arginine 2 in vitro, Xiongwen Cao, Charlie Degui Chen, 2015
- Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway, Xiongwen Cao, Jing-Dong J. Han, 2011
Awards
- 2022: Shanghai Pujiang Talent
- 2022: Zijiang Young Scholar
