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Wei Dong Li
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English, Japanese
Neuroscience
Memory
Depression
Psychology
Epilepsy
Epigenetics
Transgenic Mice
Optogenetics
Chemogenetics
Neural Circuits
Areas of Focus
- Neural mechanisms of negative emotional memory and forgetting
- Mechanisms of depression onset and treatment
- Brain mechanisms of psychological laws
- Non-human primate models of epilepsy
- Epigenetics of learning and memory
Work Experience
- 2001-2002 Part-time Lecturer: Shinshu University, Japan
- 2002-2007 Postdoctoral Researcher: University of California, Los Angeles
- 2007-2010 Assistant Researcher: University of California, Los Angeles
Academic Background & Achievements
- 1990-1996 Bachelor: China Medical University
- 1997-2001 PhD: Shinshu University, Japan
- Distinguished Professor (Eastern Scholar) at Shanghai Universities, Outstanding Academic Leader of Shanghai
Publications
- Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice, Liu, Z., Li, C., Fan, X., Kuang, Y., Zhang, X., Chen, L., ... & Li, W*., 2020
- Mental health of young physicians in China during the novel coronavirus disease 2019 outbreak, Li, W.#*, Frank, E.#, Zhao, Z.#, Chen, L., Wang, Z., Burmeister, M., & Sen, S*., 2020
- Dysregulation of neuron differentiation in an autistic savant with exceptional memory, Song, J., Yang, X., Zhou, Y., Chen, L., Zhang, X., Liu, Z., ... & Li, W*., 2019
- Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice, Li W, Zhou Y, Jentsch J. D, Ehninger D, Brown R.A.M, Tian X , Hennah W, Peltonen L, Lönnqvist J, Huttunen M.O, Kaprio J, Trachtenberg J.T, Silva A. J, Cannon T. D., 2007
- The HMG-CoA reductase inhibitor, lovastatin, reverses the learning and attention deficits in a mouse model of Neurofibromatosis Type 1, Li W, Y Cui , Kushner S.A, Brown R.A.M, Frankland P. W, Jentsch J. D, Cannon T. D, Silva A. J, 2005
- Simulated weightlessness procedure, head-down bed rest impairs adult neurogenesis in the hippocampus of rhesus macaque, Zhang X, Chu X, Chen L, Fu J, Wang S, Song J, Kan G, Jiang W, He G, Chen X*, Li W*., 2019
- Characterization of a novel synGAP isoform, synGAP-beta, Li W, Okano A, Tian QB, Nakayama K, Furihata T, Nawa H, Suzuki T., 2001
- Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway, Chen, X., Wang, S., Zhou, Y., Han, Y., Li, S., Xu, Q., ... Li, W.D.*, & Chen, C. D. *, 2018
- Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis, Bao H#, Asrican B#, Li W#, Gu B, Wen Z, Lim SA, Haniff I, Ramakrishnan C, Deisseroth K, Philpot B, Song J., 2017
- mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons, Zhou M#, Li W#*, Huang S, Song J, Kim JY, Tian X, Kang E, Sano Y, Liu C, Balaji J, Wu S, Zhou Y, Zhou Y, Parivash SN, Ehninger D, He L, Song H, Ming GL, Silva AJ*., 2013
Awards
- NARSAD Young Investigator Award
- Children's Tumor Foundation Young Investigator Award
- 2011 Shanghai Pujiang Talent Plan
- Shanghai Dawn Program
