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Xipeng Liu
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English, French
Dna Replication
Dna Repair
Extremophiles
Nucleic Acid Metabolism
Cancer
Molecular Diagnostics
Genetic Resources
Crispr
Gene Editing
Molecular Mechanisms
Areas of Focus
- DNA replication and damage repair in extremophiles
- Nucleic acid metabolism and its applications in cancer and molecular diagnostics
- Genetic resource mining and utilization in extremophiles
Work Experience
- 2010/06 – Present, Shanghai Jiao Tong University, School of Life Sciences and Technology, Associate Professor
- 2008/12 – 2010/05, CNRS, Centre de Genetique Moleculaire, Postdoctoral Researcher
- 2008/01 – 2008/11, Shanghai Jiao Tong University, School of Life Sciences and Technology, Associate Professor
- 2005/07 – 2007/12, Shanghai Jiao Tong University, School of Life Sciences and Technology, Lecturer
Academic Background & Achievements
- 2001/03-2005/06, PhD in Life Sciences and Technology, Shanghai Jiao Tong University, Supervisor: Professor Jianhua Liu
- 1998/09-2001/02, Master's in Biochemical Engineering, Tianjin University, Supervisor: Professor Yingjin Yuan
- 1994/09-1998/07, Bachelor's in Biochemical Engineering, Tianjin University, Supervisor: Professor Yingjin Yuan
Publications
- The trimeric Hef-associated nuclease HAN is a 3'→5' exonuclease and is probably involved in DNA repair, Feng L, Chang CC, Song D, Jiang C, Song Y, Wang CF, Deng W, Zou YJ, Chen HF, Xiao X, Wang FP, Liu XP, 2018
- The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45, Li MJ, Yi GS, Yu F, Zhou H, Chen JN, Xu CY, Wang FP, Xiao X, He JH, Liu XP, 2017
- RecJ-like protein from Pyrococcus furiosus has 3’-5’ exonuclease activity on RNA: implication of its proofreading capacity on 3’-mismatched RNA primer in DNA replication, Yuan H, Liu XP, Han Z, Allers T, Hou JL, Liu JH, 2013
- NanoRNase from Aeropyrum pernix shows nuclease activity on ssDNA and ssRNA, Deng YJ, Feng L, Zhou H, Xiao X, Wang FP, Liu XP, 2018
- Chlamydophila pneumoniae endonuclease IV prefers to remove mismatched 3' ribonucleotides: Implication in proofreading mismatched 3'-terminal nucleotides in short-patch repair synthesis, Xie JJ, Liu XP, Han Z, Yuan H, Wang Y, Hou JL, Liu JH, 2013
Awards
- Morning Star Young Scholar Award, Second Prize, Shanghai Jiao Tong University
- First Prize, National College Student Life Science Innovation and Entrepreneurship Competition (as a mentor)
