Professor | Shi Ting | Asia Growth Partners

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Name	Shi Ting
Contact Information	tshi@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Shi Ting

Contact Information

tshi@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2007.07-2010.07 Postdoctoral Fellow at Shanghai Institute of Materia Medica, Chinese Academy of Sciences Developed 'pre-reactive state' model for rapid analysis of enzyme structure-function relationships
Work Experience	2010.07-2013.06 Assistant Researcher at Shanghai Jiao Tong University School of Medicine 2013.06-2014.12 Assistant Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University 2014.12-2022.12 Associate Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University 2022.12-present Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University
Awards	2016, 2017 Shanghai Jiao Tong University 'Excellent Class Director' 2018 Second Prize in the Third Teaching Competition of the School of Life Sciences and Technology, Shanghai Jiao Tong University 2018 Third Prize in the Third Young Teachers Teaching Competition of Shanghai Jiao Tong University 2020 Third Prize as a mentor in the Fifth National College Students' Life Science Innovation and Entrepreneurship Competition

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2007.07-2010.07 Postdoctoral Fellow at Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Developed 'pre-reactive state' model for rapid analysis of enzyme structure-function relationships

Work Experience

2010.07-2013.06 Assistant Researcher at Shanghai Jiao Tong University School of Medicine
2013.06-2014.12 Assistant Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University
2014.12-2022.12 Associate Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University
2022.12-present Researcher at School of Life Sciences and Technology, Shanghai Jiao Tong University

Awards

2016, 2017 Shanghai Jiao Tong University 'Excellent Class Director'
2018 Second Prize in the Third Teaching Competition of the School of Life Sciences and Technology, Shanghai Jiao Tong University
2018 Third Prize in the Third Young Teachers Teaching Competition of Shanghai Jiao Tong University
2020 Third Prize as a mentor in the Fifth National College Students' Life Science Innovation and Entrepreneurship Competition

Areas of Focus	Enzyme catalysis mechanisms Bioinformatics analysis of enzyme structure-function relationships Microbial drug design Computational biology for molecular/atomic level analysis of key enzyme catalysis mechanisms
Publications	Molecular Insights into Bifunctional Ambruticin DH3 for Substrate Specificity and Catalytic Mechanism, Shi Ting Insight into Substrate-assisted Catalytic Mechanism and Stereoselectivity of Bifunctional Nocardicin Thioesterase, Shi Ting Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics, Shi Ting Discovery of Semi-Pinacolases from the Epoxide Hydrolase Family during Efficient Assembly of a Fungal Polyketide, Shi Ting Theoretical study on substrate recognition and catalytic mechanisms of gephyronic acid dehydratase DH1, Shi Ting Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase, Shi Ting Theoretical Investigation of the Structural Characteristics in the Active State of Akt1 Kinase, Shi Ting Theoretical Studies on the Catalytic Mechanism and Substrate Diversity for Macrocyclization of Pikromycin Thioesterase, Shi Ting

Areas of Focus

Enzyme catalysis mechanisms
Bioinformatics analysis of enzyme structure-function relationships
Microbial drug design
Computational biology for molecular/atomic level analysis of key enzyme catalysis mechanisms

Publications

Molecular Insights into Bifunctional Ambruticin DH3 for Substrate Specificity and Catalytic Mechanism, Shi Ting
Insight into Substrate-assisted Catalytic Mechanism and Stereoselectivity of Bifunctional Nocardicin Thioesterase, Shi Ting
Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics, Shi Ting
Discovery of Semi-Pinacolases from the Epoxide Hydrolase Family during Efficient Assembly of a Fungal Polyketide, Shi Ting
Theoretical study on substrate recognition and catalytic mechanisms of gephyronic acid dehydratase DH1, Shi Ting
Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase, Shi Ting
Theoretical Investigation of the Structural Characteristics in the Active State of Akt1 Kinase, Shi Ting
Theoretical Studies on the Catalytic Mechanism and Substrate Diversity for Macrocyclization of Pikromycin Thioesterase, Shi Ting

Enzyme Catalysis Mechanisms Bioinformatics Structure-Function Microbial Drug Design Computational Biology Molecular Analysis Atomic Analysis

Qi Liu - Tongji University

Xiaoou Zhang - Tongji University

Kailin Tang - Tongji University

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