Professor | Fang Wei | Asia Growth Partners

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Name	Fang Wei
Contact Information	fangwei@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Fang Wei

Contact Information

fangwei@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2000 - 2003 PhD: Chinese Academy of Medical Sciences, Cancer Institute Published over 40 SCI articles Holds patents in the US and China
Work Experience	2013 - Present: Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology 2010 - 2013: Research Assistant, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute 2008 - 2010: Postdoctoral Fellow, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute 2005 - 2008: Postdoctoral Fellow, University of Pennsylvania, School of Veterinary Medicine, Comparative Oncology and Animal Biology Department 2003 - 2005: Research Assistant, University of Virginia, Department of Chemistry
Awards	2021: Third Prize, Sixth Teaching Competition, School of Life Sciences 2014: Shanghai Pujiang Talent 2012: Outstanding Paper Award, FOCiS International Conference 2003: Second Prize, Medical Progress, Chinese Medical Association 2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences 2002: Second Prize, Tianheng Cup, Cancer Institute, Chinese Academy of Medical Sciences

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2000 - 2003 PhD: Chinese Academy of Medical Sciences, Cancer Institute
Published over 40 SCI articles
Holds patents in the US and China

Work Experience

2013 - Present: Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology
2010 - 2013: Research Assistant, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute
2008 - 2010: Postdoctoral Fellow, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute
2005 - 2008: Postdoctoral Fellow, University of Pennsylvania, School of Veterinary Medicine, Comparative Oncology and Animal Biology Department
2003 - 2005: Research Assistant, University of Virginia, Department of Chemistry

Awards

2021: Third Prize, Sixth Teaching Competition, School of Life Sciences
2014: Shanghai Pujiang Talent
2012: Outstanding Paper Award, FOCiS International Conference
2003: Second Prize, Medical Progress, Chinese Medical Association
2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences
2002: Second Prize, Tianheng Cup, Cancer Institute, Chinese Academy of Medical Sciences

Areas of Focus	Oncogenesis and immunotherapy Chronic viral and tumor immune evasion
Publications	CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F, 2018 Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, Riley JR, 2013 STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q, 2018 Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q, 2019 Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F, 2019 Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F, Xiaojing Ma, 2019 Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F, Wei F, Cai Q, 2020 B7-H3 Chimeric Antigen Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F, 2020 Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F, 2023 UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F, 2022

Areas of Focus

Oncogenesis and immunotherapy
Chronic viral and tumor immune evasion

Publications

CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F, 2018
Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, Riley JR, 2013
STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q, 2018
Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q, 2019
Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F, 2019
Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F, Xiaojing Ma, 2019
Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F, Wei F, Cai Q, 2020
B7-H3 Chimeric Antigen Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F, 2020
Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F, 2023
UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F, 2022

Oncogenesis Immunotherapy Tumor Immune Evasion Chronic Viral Development Therapy Cancer

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