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Fang Wei
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Oncogenesis
Immunotherapy
Tumor
Immune
Evasion
Chronic
Viral
Development
Therapy
Cancer
Areas of Focus
- Oncogenesis and immunotherapy
- Chronic viral and tumor immune evasion
Work Experience
- 2013 - Present: Associate Researcher, Shanghai Jiao Tong University, School of Life Sciences and Technology
- 2010 - 2013: Research Assistant, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute
- 2008 - 2010: Postdoctoral Fellow, University of Pennsylvania, School of Medicine, Abramson Cancer Research Institute
- 2005 - 2008: Postdoctoral Fellow, University of Pennsylvania, School of Veterinary Medicine, Comparative Oncology and Animal Biology Department
- 2003 - 2005: Research Assistant, University of Virginia, Department of Chemistry
Academic Background & Achievements
- 2000 - 2003 PhD: Chinese Academy of Medical Sciences, Cancer Institute
- Published over 40 SCI articles
- Holds patents in the US and China
Publications
- CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions, Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F, 2018
- Strength of PD-1 Signaling Differentially Affects T Cell Effector Functions, Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman G, Krogsgaard M, Riley JR, 2013
- STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus, Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q, 2018
- Viral-Mediated AURKB Cleavage Promotes Cell Segregation and Tumorigenesis, Zhu Q, Ding L, Zi Z, Gao S, Wang C, Wang Y, Zhu C, Yuan Z, Wei F, Cai Q, 2019
- Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Li G, Ding L, Ma X, Cai Q, Ying T, Wei F, 2019
- Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment, Voshtani R, Song M, Wang H, Li X, Zhang W, Tavallaie M, Yan W, Sun J, Wei F, Xiaojing Ma, 2019
- Lactate induces production of tRNAHis half to promote B-lymphoblastic cell proliferation, Mo X, Du S, Chen X, Wang Y, Liu X, Zhang C, Zhu C, Ding L, Li Y, Tong Y, Ju Q, Qu D, Tan F, Wei F, Cai Q, 2020
- B7-H3 Chimeric Antigen Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma, Zi Z, Zhao H, Wang H, Ma X, Wei F, 2020
- Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability, Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y, Zhou F, Tong Y, Riley JL, Cai Q, Ma X, Wei F, 2023
- UBR5 promotes tumor immune evasion through enhancing IFN-g-induced PDL1 transcription in triple negative breast cancer, Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F, 2022
Awards
- 2021: Third Prize, Sixth Teaching Competition, School of Life Sciences
- 2014: Shanghai Pujiang Talent
- 2012: Outstanding Paper Award, FOCiS International Conference
- 2003: Second Prize, Medical Progress, Chinese Medical Association
- 2002: Outstanding Paper, Annual Meeting of the Chinese Academy of Medical Sciences
- 2002: Second Prize, Tianheng Cup, Cancer Institute, Chinese Academy of Medical Sciences
