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Zhigang Xie
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Autophagy
Molecular Biology
Cell Biology
Gene Discovery
Molecular Mechanism
Signal Transduction
Disease Role
Therapeutic Intervention
Eukaryotic Cells
Subcellular Degradation
Areas of Focus
- Autophagy
Work Experience
- 2014-Present: Shanghai Jiao Tong University, School of Life Sciences and Technology, Researcher, Doctoral Supervisor
- 2009-2014: Nankai University, Medical School, Associate Professor (Independent PI)
- 2008-2009: University of Michigan, Ann Arbor, Life Sciences Institute, Postdoctoral Researcher
Academic Background & Achievements
- 2001-2008: PhD in Molecular Cellular Developmental Biology, University of Michigan, Ann Arbor
- 1997-2001: Dual Bachelor's in Biochemistry and Molecular Biology, Peking University
- 2012: Received the National Science Foundation's Excellent Young Scientist Fund, selected for the Ministry of Education's New Century Excellent Talents Program
Publications
- Membrane recruitment of Atg8 by Hfl1 facilitates turnover of vacuolar membrane proteins in yeast cells approaching stationary phase, He CW, Cui XF, Ma SJ, Xu Q, Ran YP, Chen WZ, Mu JX, Li H, Zhu J, Gong Q, Xie Z*, 2021
- Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy, Li D, Yang SG, He CW, Zhang ZT, Liang Y, Li H, Zhu J, Su X*, Gong Q*, Xie Z*, 2020
- A Validated Set of Fluorescent-Protein-Based Markers for Major Organelles in Yeast (Saccharomyces cerevisiae), Zhu J, Zhang ZT, Tang SW, Zhao BS, Li H, Song JZ, Li D, Xie Z*, 2019
- The Ccl1-Kin28 kinase complex regulates autophagy under nitrogen starvation, Zhu J, Deng S, Lu P, Bu W, Li T, Yu L*, Xie Z*, 2016
- A fluorescent tool set for yeast Atg proteins, Li D, Song JZ, Li H, Shan MH, Liang Y, Zhu J, Xie Z*, 2015
- Storage lipid synthesis is necessary for autophagy induced by nitrogen starvation, Li D, Song JZ, Li H, Shan MH, Liang Y, Zhu J, Xie Z*, 2015
- Estimating the size and number of autophagic bodies by electron microscopy, Backues SK, Chen D, Ruan J, Xie Z*, Klionsky DJ*, 2014
- Deficiency of hepatocystin induces autophagy through an mTOR-dependent pathway, Yang J, Zhao Y, Ma K, Jiang FJ, Liao W, Zhang P, Zhou J, Tu B, Wang L, Kampinga HH, Xie Z*, Zhu WG*, 2011
- Trs130 participates in autophagy through GTPases Ypt31/32 in Saccharomyces cerevisiae, Zou S, Chen Y, Liu Y, Segev N, Yu S, Liu Y, Min G, Ye M, Zeng Y, Zhu X, Hong B, Björn LO, Liang Y*, Li S* and Xie Z*, 2013
- Dual Roles of Atg8−PE Deconjugation by Atg4 in Autophagy, Yu ZQ, Ni T, Hong B, Wang HY, Jiang FJ, Zou S, Chen Y, Zheng XL, Klionsky DJ, Liang Y, Xie Z*, 2012
Awards
- 2012: National Science Foundation's Excellent Young Scientist Fund
- 2012: Selected for the Ministry of Education's New Century Excellent Talents Program
