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Jian-Ting Zheng
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Structural Enzymology
Microbial Synthases
Natural Products
X-Ray Crystallography
Organic Chemistry
Biochemistry
Molecular Biology
Enzyme Structure
Pathway Engineering
Molecular Mechanism
Areas of Focus
- Structural enzymology of microbial natural product synthases
- Transcriptional regulation in Streptomyces
Work Experience
- Current - Shanghai Jiao Tong University - Special Research Fellow, Doctoral Supervisor
Academic Background & Achievements
- Bachelor in Microbiology: Shandong University
- PhD in Biochemistry and Molecular Biology: Institute of Microbiology, Chinese Academy of Sciences
- Postdoctoral Research: University of Maryland, Park and University of Texas at Austin
- Researcher at the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
Publications
- Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces, Wang Y., Yang X., Yu F., Deng Z., Lin S. & Zheng J., 2024
- Structural and computational insights into the regioselectivity of SpnK involved in rhamnose methylation of spinosyn, Huang, S., Ji, H. & Zheng, J., 2023
- Structural basis of Streptomyces transcription activation by zinc uptake regulator, Yang, X.; Wang, Y.; Liu, G.; Deng, Z.; Lin, S.; Zheng, J, 2022
- Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain, Zhou YC, Tao WT, Qi Z, Wei JH, Shi T, Kang QJ, Zheng JT, Zhao YL, Bai LQ, 2022
- The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases, Feng Y, Yang X, Ji H, Deng Z, Lin S, Zheng J, 2022
- Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations, Ali I, Khan A, Fa Z, Khan T, Wei DQ, Zheng J, 2022
- Computational Studies on the Substrate Specificity of an Acyltransferase Domain from Salinomycin Polyketide Synthase, Ji H, Shi T, Liu L, Zhang F, Tao W, Min Q, Deng Z, Bai L, Zhao Y, Zheng J, 2021
- Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis, He, B.-B., Zhou, T., Bu, X.-L., Weng, J.-Y., Xu, J., Lin, S., Zheng, J.-T., Zhao, Y.-L. & Xu, M.-J., 2019
- Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases, Zhang, L., Ji, J., Yuan, M., Feng, Y., Wang, L., Deng, Z., Bai, L. & Zheng, J., 2018
