Professor | Jian-Ting Zheng | Asia Growth Partners

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Name	Jian-Ting Zheng
Contact Information	jtzheng@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

Upload Avatar (500 x 500)

Name

Jian-Ting Zheng

Contact Information

jtzheng@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	Bachelor in Microbiology: Shandong University PhD in Biochemistry and Molecular Biology: Institute of Microbiology, Chinese Academy of Sciences Postdoctoral Research: University of Maryland, Park and University of Texas at Austin Researcher at the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences
Work Experience	Current - Shanghai Jiao Tong University - Special Research Fellow, Doctoral Supervisor

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

Bachelor in Microbiology: Shandong University
PhD in Biochemistry and Molecular Biology: Institute of Microbiology, Chinese Academy of Sciences
Postdoctoral Research: University of Maryland, Park and University of Texas at Austin
Researcher at the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences

Work Experience

Current - Shanghai Jiao Tong University - Special Research Fellow, Doctoral Supervisor

Areas of Focus	Structural enzymology of microbial natural product synthases Transcriptional regulation in Streptomyces
Publications	Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces, Wang Y., Yang X., Yu F., Deng Z., Lin S. & Zheng J., 2024 Structural and computational insights into the regioselectivity of SpnK involved in rhamnose methylation of spinosyn, Huang, S., Ji, H. & Zheng, J., 2023 Structural basis of Streptomyces transcription activation by zinc uptake regulator, Yang, X.; Wang, Y.; Liu, G.; Deng, Z.; Lin, S.; Zheng, J, 2022 Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain, Zhou YC, Tao WT, Qi Z, Wei JH, Shi T, Kang QJ, Zheng JT, Zhao YL, Bai LQ, 2022 The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases, Feng Y, Yang X, Ji H, Deng Z, Lin S, Zheng J, 2022 Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations, Ali I, Khan A, Fa Z, Khan T, Wei DQ, Zheng J, 2022 Computational Studies on the Substrate Specificity of an Acyltransferase Domain from Salinomycin Polyketide Synthase, Ji H, Shi T, Liu L, Zhang F, Tao W, Min Q, Deng Z, Bai L, Zhao Y, Zheng J, 2021 Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis, He, B.-B., Zhou, T., Bu, X.-L., Weng, J.-Y., Xu, J., Lin, S., Zheng, J.-T., Zhao, Y.-L. & Xu, M.-J., 2019 Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases, Zhang, L., Ji, J., Yuan, M., Feng, Y., Wang, L., Deng, Z., Bai, L. & Zheng, J., 2018

Areas of Focus

Structural enzymology of microbial natural product synthases
Transcriptional regulation in Streptomyces

Publications

Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces, Wang Y., Yang X., Yu F., Deng Z., Lin S. & Zheng J., 2024
Structural and computational insights into the regioselectivity of SpnK involved in rhamnose methylation of spinosyn, Huang, S., Ji, H. & Zheng, J., 2023
Structural basis of Streptomyces transcription activation by zinc uptake regulator, Yang, X.; Wang, Y.; Liu, G.; Deng, Z.; Lin, S.; Zheng, J, 2022
Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain, Zhou YC, Tao WT, Qi Z, Wei JH, Shi T, Kang QJ, Zheng JT, Zhao YL, Bai LQ, 2022
The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases, Feng Y, Yang X, Ji H, Deng Z, Lin S, Zheng J, 2022
Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations, Ali I, Khan A, Fa Z, Khan T, Wei DQ, Zheng J, 2022
Computational Studies on the Substrate Specificity of an Acyltransferase Domain from Salinomycin Polyketide Synthase, Ji H, Shi T, Liu L, Zhang F, Tao W, Min Q, Deng Z, Bai L, Zhao Y, Zheng J, 2021
Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis, He, B.-B., Zhou, T., Bu, X.-L., Weng, J.-Y., Xu, J., Lin, S., Zheng, J.-T., Zhao, Y.-L. & Xu, M.-J., 2019
Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases, Zhang, L., Ji, J., Yuan, M., Feng, Y., Wang, L., Deng, Z., Bai, L. & Zheng, J., 2018

Structural Enzymology Microbial Synthases Natural Products X-Ray Crystallography Organic Chemistry Biochemistry Molecular Biology Enzyme Structure Pathway Engineering Molecular Mechanism

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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