Professor | Jinwei Zhu | Asia Growth Partners

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Name	Jinwei Zhu
Contact Information	jinwei.zhu@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jinwei Zhu

Contact Information

jinwei.zhu@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2005-09 to 2010-07, PhD in Chemical Biology, Fudan University, Supervisor: Mingjie Zhang 2001-09 to 2005-07, Bachelor in Chemistry, Nankai University
Work Experience	2022-06 to present, Shanghai Jiao Tong University, Bio-X Institute, Researcher 2019-09 to 2022-06, Shanghai Jiao Tong University, Bio-X Institute, Associate Professor 2013-09 to 2019-09, Shanghai Institute for Biological Sciences, CAS, Associate Researcher 2010-09 to 2013-09, Hong Kong University of Science and Technology, Postdoctoral Fellow, Supervisor: Mingjie Zhang
Awards	2020 Yangtze River Delta Neuroscience Young Scientist Award 2021 First Prize in the Sixth Young Teachers Teaching Competition at Shanghai Jiao Tong University, Natural Science and Medical Science Group

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2005-09 to 2010-07, PhD in Chemical Biology, Fudan University, Supervisor: Mingjie Zhang
2001-09 to 2005-07, Bachelor in Chemistry, Nankai University

Work Experience

2022-06 to present, Shanghai Jiao Tong University, Bio-X Institute, Researcher
2019-09 to 2022-06, Shanghai Jiao Tong University, Bio-X Institute, Associate Professor
2013-09 to 2019-09, Shanghai Institute for Biological Sciences, CAS, Associate Researcher
2010-09 to 2013-09, Hong Kong University of Science and Technology, Postdoctoral Fellow, Supervisor: Mingjie Zhang

Awards

2020 Yangtze River Delta Neuroscience Young Scientist Award
2021 First Prize in the Sixth Young Teachers Teaching Competition at Shanghai Jiao Tong University, Natural Science and Medical Science Group

Areas of Focus	Neurosignal transduction and plasticity Structural basis of glomerular filtration barrier Biochemical and structural mechanisms of synapse development; molecular mechanisms of synaptic plasticity; structural biology of neuropsychiatric disorders
Publications	Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs, Zhang M, Cao A, Lin L, Chen Y, Shang Y, Wang C, Zhang MJ, Zhu J, 2023 Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein-protein interaction inhibitor, Gu J, Peng R, Guo C, Zhang M, Yang J, Yan X, Zhou Q, Li H, Wang N, Zhu J, Ouyang Q, 2022 Promotion of row 1-specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia, Shi Y, Lin L, Wang C, Zhu J, 2022 Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex, Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J, Zhang R, 2021 Double inhibition and activation mechanisms of Ephexin family RhoGEFs, Zhang M, Lin L, Wang C, Zhu J, 2021 Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability, Wang M, Lin L, Shi Y, He L, Wang C, Zhu J, 2020 GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling, Zhu J, Zhou Q, Xia Y, Lin L, Li J, Peng M, Zhang R, Zhang M, 2020 Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds, Weng Z, Situ C, Lin L, Wu Z, Zhu J, Zhang R, 2019 Structural basis of highly specific interaction between Nephrin and MAGI1 in slit diaphragm assembly and signaling, Weng Z, Shang Y, Ji Z, Ye F, Lin L, Zhang R, Zhu J, 2018 Structure of PSD95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain, Xia Y, Shang Y, Zhang R, Zhu J, 2017

Areas of Focus

Neurosignal transduction and plasticity
Structural basis of glomerular filtration barrier
Biochemical and structural mechanisms of synapse development; molecular mechanisms of synaptic plasticity; structural biology of neuropsychiatric disorders

Publications

Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs, Zhang M, Cao A, Lin L, Chen Y, Shang Y, Wang C, Zhang MJ, Zhu J, 2023
Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein-protein interaction inhibitor, Gu J, Peng R, Guo C, Zhang M, Yang J, Yan X, Zhou Q, Li H, Wang N, Zhu J, Ouyang Q, 2022
Promotion of row 1-specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia, Shi Y, Lin L, Wang C, Zhu J, 2022
Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex, Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J, Zhang R, 2021
Double inhibition and activation mechanisms of Ephexin family RhoGEFs, Zhang M, Lin L, Wang C, Zhu J, 2021
Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability, Wang M, Lin L, Shi Y, He L, Wang C, Zhu J, 2020
GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling, Zhu J, Zhou Q, Xia Y, Lin L, Li J, Peng M, Zhang R, Zhang M, 2020
Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds, Weng Z, Situ C, Lin L, Wu Z, Zhu J, Zhang R, 2019
Structural basis of highly specific interaction between Nephrin and MAGI1 in slit diaphragm assembly and signaling, Weng Z, Shang Y, Ji Z, Ye F, Lin L, Zhang R, Zhu J, 2018
Structure of PSD95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain, Xia Y, Shang Y, Zhang R, Zhu J, 2017

Neuroscience Signal Transduction Plasticity Glomerular Filtration Synapse Development Synaptic Plasticity Molecular Mechanisms Neuropsychiatric Disorders Structural Biology Biochemistry

Fang Yu - Shanghai Normal University

Lu Qing - Shanghai Jiao Tong University

Geng Wu - Shanghai Jiao Tong University

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