Areas of Focus
- Biomechanics and mechanobiology research focusing on mechanosensitive receptors mediating stem cell differentiation, tumor invasion, and immunotherapy
Work Experience
- 2019-Present: Professor, School of Life Sciences and Technology, Xi'an Jiaotong University
- 2016-2019: Associate Professor, School of Life Sciences and Technology, Xi'an Jiaotong University
- 2014-2015: Postdoctoral Researcher, Harvard Medical School/Massachusetts General Hospital
- 2011-2015: Lecturer, School of Life Sciences and Technology, Xi'an Jiaotong University
Academic Background & Achievements
- B.S. in Material Science and Engineering, Hefei University of Technology (2001-2005)
- M.S. in Material Science and Engineering, Xi'an Jiaotong University (2006-2008)
- Ph.D. in Mechanics (Biomechanics), Xi'an Jiaotong University (2008-2011)
- Postdoctoral Researcher, Harvard Medical School/Massachusetts General Hospital (2014-2015)
- Recipient of the National Science Fund for Distinguished Young Scholars
Publications
- Programmable and reversible integrin‐mediated cell adhesion reveals hysteresis in actin kinetics that alters subsequent mechanotransduction, Zhang Z, Zhu H Y, Zhao G Q, Miao Y Y, Zhao L Z, Feng J T, Zhang H, Miao R, Sun L, Gao B, Zhang W C, Wang Z, Zhang J F, Zhang Y, Guo H, Xu F, Lu T J, Genin G M, Lin M, 2023
- Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation, Zhang Z, Sha B Y, Zhao L Z, Zhang H, Feng J T, Zhang C, Sun L, Luo M Q, Gao B, Guo H, Wang Z, Xu F, Lu T J, Genin G M, Lin M, 2022
- Directed cell migration toward softer environments, A. Isomursu, K.Y. Park, J. Hou, B. Cheng, M. Mathieu, G. Shamsan, B.J Fuller, J. Kasim, M. M. Mahmoodi, T.J.Lu, G.M. Genin, F. Xu, M. Lin, M. Distefano, J. Ivaska, D.J. Odde, 2022
- Reprogramming of activated pancreatic stellate cells via mechanical modulation of transmembrane force-sensitive N-cadherin Receptor, H. Zhang, H.Y. Zhu, J.T. Feng, Z. Zhang, S.M. Zhang, Z. Wang, L. Sun, W.C. Zhang, B. Gao, Y. Zhang, M. Lin, 2022
- Cellular mechanosensing of texture features, M. Lin, 2022
- 力敏感受体介导细胞功能调控的力学生物学研究, 张欢, 赵国清, 冯锦腾, 林敏, 2022
- Mechanics-driven nuclear localization of YAP can be reversed by N-cadherin ligation in mesenchymal stem cells, C. Zhang, H.Y Zhu, X.R. Ren, B. Gao, B. Cheng, S.B. Liu, B.Y. Sha, Z.Q. Li, Z. Zhang, Y. Lv, H.H. Wang, H. Guo, T.J. Lu, F. Xu, G.M. Genin, M. Lin, 2021
- Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation, B. Cheng, W. Wan, G. Huang, Y. Li, G.M. Genin, M.R.K. Mofrad, T.J. Lu, F. Xu, M. Lin, 2020
- Spatiotemporally controlled photoresponsive hydrogels: design and predictive modeling from processing through application, H.Y. Zhu, H.Q. Yang, Y.F. Ma, T.J. Lu, F. Xu, G.M. Genin, M. Lin, 2020
- Synergistic effect of matrix stiffness and inflammatory factors on osteogenic differentiation of MSC, W.T. Wan, B. Cheng, C. Zhang, Y.F. Ma, A. Li, F. Xu, M. Lin, 2019
Awards
- National Science Fund for Distinguished Young Scholars
- Shaanxi Youth Science and Technology Award
- Shaanxi Youth Science and Technology Star
- Xi'an Youth Science and Technology Talent