Professor | Dan Xu | Asia Growth Partners

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Name	Dan Xu
Contact Information	dan.xu@xjtu.edu.cn
Language ability	Chinese, English
Province	Shaanxi

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Name

Dan Xu

Contact Information

dan.xu@xjtu.edu.cn

Language ability

Chinese, English

Province

Shaanxi

University/Lab Affiliation and Title	Xi'an Jiaotong University
Faculty	Life Sciences
Academic Background & Achievements	2003 - 2007 BSc-MSc Integrated Program in Life Sciences and Technology, Xi'an Jiaotong University 2007 - 2013 PhD in Biology, Xi'an Jiaotong University 2009 - 2011 CSC Joint PhD Training, University of Strathclyde, UK, Microbiology Published 10 SCI papers as first/corresponding author, highest impact factor 31.745 Holds 1 national patent, received second-class Shaanxi Province Science and Technology Award
Work Experience	2023-Present Professor, School of Life Sciences, Xi'an Jiaotong University, Microbiology 2016-2022 Associate Professor, School of Life Sciences, Xi'an Jiaotong University 2018-2020 Postdoctoral Fellow/Visiting Scholar, University of Maryland School of Medicine/Institut Pasteur, France 2013-2016 Lecturer, School of Life Sciences, Xi'an Jiaotong University
Awards	National Patent (Year not mentioned): Detail not mentioned Second-class Shaanxi Province Science and Technology Award (Year not mentioned): Third co-author

University/Lab Affiliation and Title

Xi'an Jiaotong University

Faculty

Life Sciences

Academic Background & Achievements

2003 - 2007 BSc-MSc Integrated Program in Life Sciences and Technology, Xi'an Jiaotong University
2007 - 2013 PhD in Biology, Xi'an Jiaotong University
2009 - 2011 CSC Joint PhD Training, University of Strathclyde, UK, Microbiology
Published 10 SCI papers as first/corresponding author, highest impact factor 31.745
Holds 1 national patent, received second-class Shaanxi Province Science and Technology Award

Work Experience

2023-Present Professor, School of Life Sciences, Xi'an Jiaotong University, Microbiology
2016-2022 Associate Professor, School of Life Sciences, Xi'an Jiaotong University
2018-2020 Postdoctoral Fellow/Visiting Scholar, University of Maryland School of Medicine/Institut Pasteur, France
2013-2016 Lecturer, School of Life Sciences, Xi'an Jiaotong University

Awards

National Patent (Year not mentioned): Detail not mentioned
Second-class Shaanxi Province Science and Technology Award (Year not mentioned): Third co-author

Areas of Focus	Gut microbiome interactions with host and immune system based on multi-omics data analysis Pathogenic mechanisms and immune factors of enteropathogens, particularly Shigella
Publications	Inhibitory effects of a water-soluble jujube polysaccharide against biofilm-forming oral pathogenic bacteria, Dan Xu , Jiu Xiao , Dazhao Jiang , Yaxin Liu , Zhuolun Gou , Jing Li , Mingyao Shi , Xinyi Wang, Yaxuan Guo , Lingyan Ma, Hong Yin, Li Guo , Chunhui Zhu, Yali Zhang , Hui Guo , 2022 MiR-365-3p is a Negative Regulator in IL-17-mediated Asthmatic Inflammation, Weijia Wang, Ying Li, Jiaqi Fan, Xiaoyan Qu, Dong Shang, Qiaohong Qin,Tun Xu, Qutayba Hamid, Xiaomin Dang, Ying Chang, Dan Xu , 2022 Defensins: A double-edged sword in host immunity, Dan Xu, Wuyuan Lu, 2020 Human enteric defensin 5 promotes Shigella infection in macrophage, Dan Xu, Chongbing Liao, Jiu Xiao, Kun Fang, Wei Zhang, Weirong Yuan, Wuyuan Lu, 2019 Critical determinants of human neutrophil peptide 1 for enhancing host epithelial adhesion of Shigella flexneri, Chongbing Liao, Kun Fang, Jiu Xiao, Wei Zhang, Bing Zhang, Weirong Yuan, Wuyuan Lu, Dan Xu*, 2019 Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion, Dan Xu, Chongbing Liao, Bing Zhang, W. David Tolbert, Wangxiao He, Zhijun Dai, Wei Zhang, Weirong Yuan, Marzena Pazgier, Jun Yu, Philippe J. Sansonetti, Charles L. Bevins, Yongping Shao, Wuyuan Lu, 2018 Characterization of a biofilm-forming Shigella flexneri phenotype due to deficiency in Hep biosynthesis, Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang, Yongping Shao, 2016 Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling, Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang, Yongping Shao, 2016 Surface display of the HPV L1 capsid protein by the autotransporter ShigellaIcsA, Dan Xu, Xiaofeng Yang, Depu Wang, Jun Yu, Yili Wang, 2014 Fusion of HPV L1 into Shigella surface IcsA: a new approach in developing live attenuated Shigella-HPV vaccine, Dan Xu, Depu Wang, Xiaofeng Yang, Meng Cao, Jun Yu, Yili Wang, 2014 Cytotoxicity of gold-nanorods to human HEp-2 and canine MDCK cells, Dan Xu, Amir Saeed, Yili Wang, Veronique Seidel, Gunnar Sandström, Jun Yu, 2012 Natural products modulate Shigella host-cell interaction, Dan Xu, Amir Saeed, Yili Wang, Veronique Seidel, Gunnar Sandström, Jun Yu, 2011

Areas of Focus

Gut microbiome interactions with host and immune system based on multi-omics data analysis
Pathogenic mechanisms and immune factors of enteropathogens, particularly Shigella

Publications

Inhibitory effects of a water-soluble jujube polysaccharide against biofilm-forming oral pathogenic bacteria, Dan Xu *, Jiu Xiao , Dazhao Jiang , Yaxin Liu , Zhuolun Gou , Jing Li , Mingyao Shi , Xinyi Wang, Yaxuan Guo , Lingyan Ma, Hong Yin, Li Guo , Chunhui Zhu, Yali Zhang *, Hui Guo *, 2022
MiR-365-3p is a Negative Regulator in IL-17-mediated Asthmatic Inflammation, Weijia Wang, Ying Li, Jiaqi Fan, Xiaoyan Qu, Dong Shang, Qiaohong Qin,Tun Xu, Qutayba Hamid, Xiaomin Dang, Ying Chang*, Dan Xu *, 2022
Defensins: A double-edged sword in host immunity, Dan Xu*, Wuyuan Lu*, 2020
Human enteric defensin 5 promotes Shigella infection in macrophage, Dan Xu*, Chongbing Liao, Jiu Xiao, Kun Fang, Wei Zhang, Weirong Yuan, Wuyuan Lu*, 2019
Critical determinants of human neutrophil peptide 1 for enhancing host epithelial adhesion of Shigella flexneri, Chongbing Liao, Kun Fang, Jiu Xiao, Wei Zhang, Bing Zhang, Weirong Yuan, Wuyuan Lu*, Dan Xu*, 2019
Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion, Dan Xu, Chongbing Liao, Bing Zhang, W. David Tolbert, Wangxiao He, Zhijun Dai, Wei Zhang, Weirong Yuan, Marzena Pazgier, Jun Yu, Philippe J. Sansonetti, Charles L. Bevins, Yongping Shao, Wuyuan Lu, 2018
Characterization of a biofilm-forming Shigella flexneri phenotype due to deficiency in Hep biosynthesis, Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang, Yongping Shao, 2016
Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling, Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang, Yongping Shao, 2016
Surface display of the HPV L1 capsid protein by the autotransporter ShigellaIcsA, Dan Xu, Xiaofeng Yang, Depu Wang, Jun Yu, Yili Wang, 2014
Fusion of HPV L1 into Shigella surface IcsA: a new approach in developing live attenuated Shigella-HPV vaccine, Dan Xu, Depu Wang, Xiaofeng Yang, Meng Cao, Jun Yu, Yili Wang, 2014
Cytotoxicity of gold-nanorods to human HEp-2 and canine MDCK cells, Dan Xu, Amir Saeed, Yili Wang, Veronique Seidel, Gunnar Sandström, Jun Yu, 2012
Natural products modulate Shigella host-cell interaction, Dan Xu, Amir Saeed, Yili Wang, Veronique Seidel, Gunnar Sandström, Jun Yu, 2011

Microbiome Host Interaction Immune System Multi-Omics Data Analysis Enteropathogens Shigella Pathogenic Mechanisms Immune Factors Disease Prevention

Wang Tao - Shanghai Jiao Tong University

Kefu Liu - Central South University

Min Liu - Peking University

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