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Jing Wu
Life Science
Xi'an Jiaotong University
Shaanxi
Language: Chinese, English
Biochemistry
Cell Biology
Pathogenesis
Cancer
Aging
Metabolic Regulation
Signal Transduction
Disease Mechanisms
Molecular Biology
Cellular Processes
Areas of Focus
- Biochemistry and Cell Biology
- Pathogenesis of diseases such as cancer and aging
- Metabolic regulation and signal transduction
Work Experience
- 2003-2005 - Fourth Military Medical University, Institute of Gastroenterology
- 2004-2005 - Sapporo Medical University, Visiting Scholar
- 2005-2006 - University of Pittsburgh, Department of Cell Biology & Physiology, Cancer Center, Postdoctoral Researcher
- 2006-2007 - Nemours Biomedical Research, Cardiology Research Center, Postdoctoral Researcher
- 2008-Present - Xi'an Jiaotong University, School of Life Sciences and Technology, Associate Professor
- 2011-2014 - Yale University, Comparative Medicine Center, Visiting Professor
Academic Background & Achievements
- 1997 - BSc in Medical Science from Fourth Military Medical University
- 2000 - MSc in Internal Medicine from Fourth Military Medical University
- 2003 - PhD in Gastroenterology from Fourth Military Medical University
- Exchange Scholar at the University of Hong Kong, Institute of Molecular Biology
Publications
- Regulation of the urea cycle by CPS1 O-GlcNAcylation in response to dietary restriction and aging, Wu J, Liu J, Lapenta K, Desrouleaux R, Li MD, Yang X, 2022
- OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer, Lu X, Yang P, Zhao X, Jiang M, Hu S, Ouyang Y, Zeng L, Wu J, 2019
- OGDH promotes the progression of gastric cancer by regulating mitochondrial bioenergetics and Wnt/β-catenin signal pathway, Lu X, Wu N, Yang W, Sun J, Yan K, Wu J, 2019
- O-GlcNAc signaling in cancer metabolism and epigenetics, Singh J.P., K. Zhang, J. Wu, X. Yang, 2015
- O-GlcNAc Transferase Is Critical for TLE-Mediated Repression of Canonical Wnt Signaling, Wu J, Damon B, Sadlonova A, Whisenhunt TR, Rustgi AK, Nie YZ, Paterson AJ, Yang X, 2014
- Anticancer Effect of a Curcumin Derivative B63: ROS Production and Mitochondrial Dysfunction, Zheng A, Li H, Wang X, Feng Z, Xu J, Cao K, Zhou B, Wu J*, Liu J, 2014
- Fibulin-2 Deficiency Attenuates Angiotensin II-Induced Cardiac Hypertrophy By Reducing Transforming Growth Factor-β Signaling, Zhang H, Wu J, Dong H, Khan SA, Chu ML, Tsuda T, 2014
- O-GlcNAc transferase-controlled AgRP neurons suppress browning of white fat, Ruan H.B., M.O. Dietrich, Z.W. Liu, M.D. Li, J.P. Singh, K. Qian, K. Zhang, M.R. Zimmer, J. Wu, T.L. Horvath, X. Yang, 2014
- Cracking the O-GlcNAc code in metabolism, Ruan H.B., J.P. Singh, M.D. Li, J. Wu, X. Yang, 2013
- O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability, Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J, Yates JR 3rd, Yang X, 2012
- O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression, Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X, 2012
- Loss of fibulin-2 protects against progressive ventricular dysfunction after myocardial infarction, Tsuda T, Wu J, Gao E, Joyce J, Markova D, Dong H, Liu Y, Zhang H, Zou Y, Gao F, Miller T, Koch W, Ma X, Chu ML, 2012
- Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress, Zhang L, Park CH, Wu J, Kim H, Liu W, Fujita T, Balasubramani M, Schreiber EM, Wang XF, Wan Y, 2010
- The Correlation Between Intestinal Gonadotropin-Releasing Hormone (GnRH) and Proglucagon in Hyperlipidemic Rats and Goto-Kakizaki (GK) Rats, Wang L, Wu J, Cao H, Chen R, Zhang N, Fu J, Gao B, Zhang J, Hou R, Tang C, Ji Q, 2009
Awards
- 2004-2005: Sasakawa Medical Scholarship
