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Yanwei Wu
Medicine
Shanghai University
Shanghai
Language: Chinese, English
Autoimmune Diseases
Inflammatory Diseases
Systemic Lupus Erythematosus
Multiple Sclerosis
Inflammatory Bowel Disease
Psoriasis
Non-Alcoholic Steatohepatitis
Drug Research
Viral-Host Interaction
Antiviral Drugs
Areas of Focus
- Autoimmune and inflammatory diseases
- Early events in viral infections and drug development
Work Experience
- 2016 - Present - Shanghai Institute of Materia Medica: Assistant Researcher, Associate Researcher
- 2022 - Present - Shanghai University Medical School: Associate Researcher
Academic Background & Achievements
- 2011 - Bachelor in Pharmacy: Tongji Medical College, Huazhong University of Science and Technology
- 2016 - PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Held multiple project leadership roles including national key R&D programs and grants
- Shanghai Pharmaceutical Science Technology Award (First Prize) for Basic Research
Publications
- Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way, Wu YW, Wu B, Zhang ZW, Lu HM, Fan C, Qi Q, Gao YZ, Li H, Feng CL, Zuo JP, Tang W, 2020
- A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage, Huang S, Wu Y, Zhao Z, Wu B, Sun K, Wang H, Qin L, Bai F, Leng Y, Tang W, 2021
- Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation, Wu YW, He SJ, Bai BX, Zhang LY, Xue L, Lin ZM, Yang XQ, Zhu FH, He PL, Tang W, Zuo JP, 2016
- Hemin protects against Zika virus infection by disrupting virus-endosome fusion, Xu MM, Wu B, Huang GG, Feng CL, Wang XH, Wang HY, Wu YW, Tang W, 2022
- STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion, Wu B, Xu MM, Fan C, Feng CL, Lu QK, Lu HM, Xiang CG, Bai F, Wang HY, Wu YW, Tang W, 2021
- Development of artemisinin drugs in the treatment of autoimmune diseases, Wu YW, Tang W, Zuo JP, 2016
Awards
- Shanghai Pharmaceutical Science Technology Award (First Prize): For Basic Research
