Professor | Si Chen | Asia Growth Partners

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Name	Si Chen
Language ability	Chinese, English
Province	Shanghai

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Name

Si Chen

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai University
Faculty	Medicine
Academic Background & Achievements	2017 - PhD in Pharmaceutical Analysis: Second Military Medical University (Navy Medical University), mentored by Professor Yi-Feng Chai Research funding nearly 2 million RMB
Work Experience	2016 - University of Pittsburgh: Visiting Scholar at the Computational Chemical Genomics Screening Center

University/Lab Affiliation and Title

Shanghai University

Faculty

Medicine

Academic Background & Achievements

2017 - PhD in Pharmaceutical Analysis: Second Military Medical University (Navy Medical University), mentored by Professor Yi-Feng Chai
Research funding nearly 2 million RMB

Work Experience

2016 - University of Pittsburgh: Visiting Scholar at the Computational Chemical Genomics Screening Center

Areas of Focus	AI-based targeted drug development, mainly peptides AI-based drug analysis method development
Publications	Multimodal data fusion for supervised learning-based identification of USP7 inhibitors: a systematic comparison, Shen, Wen-Feng; Tang, He-Wei; Li, Jia-Bo; Li, Xiang; Chen, Si, 2023 Lipophilic Constituents in Salvia miltiorrhiza Inhibit Activation of the Hepatic Stellate Cells by Suppressing the JAK1/STAT3 Signaling Pathway: A Network Pharmacology Study and Experimental Validation, Tang, Ya-Xin; Liu, Mingming; Liu, Long; Zhen, Bo-Rui; Wang, Tian-Tian; Li, Na; Lv, Nanning; Zhu, Zhenyu; Sun, Guoquan; Wang, Xiaobo; Chen, Si, 2022 Design of stapled peptide-based PROTACs for MDM2 / MDMX atypical degradation and tumor suppression, Chen, Si; Li, Xiang; Li, Yinghua; Yuan, Xing; Geng, Chenchen; Gao, Songyan; Li, Jinyang; Ma, Bohan; Wang, Zhe; Lu, Wuyuan; Hu, Honggang, 2022 Stapled Helical Peptides Bearing Different Anchoring Residues, Li, Xiang; Chen, Si; Zhang, Wei Dong; Hu, Hong Gang, 2020 Discovery of Novel Ligands for TNF-alpha and TNF Receptor-1 through Structure-Based Virtual Screening and Biological Assay, Chen, Si; Feng, Zhiwei; Wang, Yun; Ma, Shifan; Hu, Ziheng; Yang, Peng; Chai, Yifeng; Xie, Xiangqun, 2017

Areas of Focus

AI-based targeted drug development, mainly peptides
AI-based drug analysis method development

Publications

Multimodal data fusion for supervised learning-based identification of USP7 inhibitors: a systematic comparison, Shen, Wen-Feng; Tang, He-Wei; Li, Jia-Bo; Li, Xiang; Chen, Si, 2023
Lipophilic Constituents in Salvia miltiorrhiza Inhibit Activation of the Hepatic Stellate Cells by Suppressing the JAK1/STAT3 Signaling Pathway: A Network Pharmacology Study and Experimental Validation, Tang, Ya-Xin; Liu, Mingming; Liu, Long; Zhen, Bo-Rui; Wang, Tian-Tian; Li, Na; Lv, Nanning; Zhu, Zhenyu; Sun, Guoquan; Wang, Xiaobo; Chen, Si, 2022
Design of stapled peptide-based PROTACs for MDM2 / MDMX atypical degradation and tumor suppression, Chen, Si; Li, Xiang; Li, Yinghua; Yuan, Xing; Geng, Chenchen; Gao, Songyan; Li, Jinyang; Ma, Bohan; Wang, Zhe; Lu, Wuyuan; Hu, Honggang, 2022
Stapled Helical Peptides Bearing Different Anchoring Residues, Li, Xiang; Chen, Si; Zhang, Wei Dong; Hu, Hong Gang, 2020
Discovery of Novel Ligands for TNF-alpha and TNF Receptor-1 through Structure-Based Virtual Screening and Biological Assay, Chen, Si; Feng, Zhiwei; Wang, Yun; Ma, Shifan; Hu, Ziheng; Yang, Peng; Chai, Yifeng; Xie, Xiangqun, 2017

Artificial Intelligence Drug Development Peptides Targeted Therapy Drug Analysis Computational Chemistry Genomics Pharmacology Biomedical Sciences Informatics

Si Chen - Shanghai University

Qiong Lai - Shanghai University

Yuemin Bian - Shanghai University

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