Professor | Wang Juan | Asia Growth Partners

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Name	Wang Juan
Language ability	Chinese, English
Province	Shanghai

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Name

Wang Juan

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai University
Faculty	Medicine
Academic Background & Achievements	2021 - PhD: Fudan University, School of Pharmacy Granted two Chinese invention patents Principal investigator for several research grants
Work Experience	2021 - Present: Shanghai University, School of Medicine - Lecturer

University/Lab Affiliation and Title

Shanghai University

Faculty

Medicine

Academic Background & Achievements

2021 - PhD: Fudan University, School of Pharmacy
Granted two Chinese invention patents
Principal investigator for several research grants

Work Experience

2021 - Present: Shanghai University, School of Medicine - Lecturer

Areas of Focus	Skin development, damage repair, aging, and fibrosis Mechanisms of skin-related disease progression Mechanisms of hair development and growth Molecular targeted drug screening and mechanism exploration
Publications	ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic, Wang J, Zhang Y, Huang WJ, Yang J, Tang WG, Huang TM, Tan W, 2021 PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation, Yang J, Wang J, Liu Y, Zhang Y, et al., 2021 IL-17 signaling in skin repair: safeguarding metabolic adaptation of wound epithelial cells, Wang J, Ding XL, 2022 The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling, Wang J, Cui BP, Chen ZJ, Ding XL, 2022 Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation, Wang J, Eming SA, Ding XL, 2022 ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli, Huang WJ, Li H, Tan WF, Wang J, 2022 Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G, Huang W, Wang J, Liu X, Yang J, Zhang Y, et al., 2017

Areas of Focus

Skin development, damage repair, aging, and fibrosis
Mechanisms of skin-related disease progression
Mechanisms of hair development and growth
Molecular targeted drug screening and mechanism exploration

Publications

ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic, Wang J, Zhang Y, Huang WJ, Yang J, Tang WG, Huang TM, Tan W, 2021
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation, Yang J, Wang J, Liu Y, Zhang Y, et al., 2021
IL-17 signaling in skin repair: safeguarding metabolic adaptation of wound epithelial cells, Wang J, Ding XL, 2022
The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling, Wang J, Cui BP, Chen ZJ, Ding XL, 2022
Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation, Wang J, Eming SA, Ding XL, 2022
ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli, Huang WJ, Li H, Tan WF, Wang J, 2022
Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G, Huang W, Wang J, Liu X, Yang J, Zhang Y, et al., 2017

Skin Development Repair Aging Fibrosis Disease Hair Growth Drug Screening Molecular

Pingzhu Zhou - Shanghai University

Pingzhu Zhou - Shanghai University

Juan Wang - Shanghai University

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