Upload Avatar (500 x 500)
Wang Juan
Medicine
Shanghai University
Shanghai
Language: Chinese, English
Skin
Development
Repair
Aging
Fibrosis
Disease
Hair
Growth
Drug Screening
Molecular
Areas of Focus
- Skin development, damage repair, aging, and fibrosis
- Mechanisms of skin-related disease progression
- Mechanisms of hair development and growth
- Molecular targeted drug screening and mechanism exploration
Work Experience
- 2021 - Present: Shanghai University, School of Medicine - Lecturer
Academic Background & Achievements
- 2021 - PhD: Fudan University, School of Pharmacy
- Granted two Chinese invention patents
- Principal investigator for several research grants
Publications
- ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic, Wang J, Zhang Y, Huang WJ, Yang J, Tang WG, Huang TM, Tan W, 2021
- PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation, Yang J, Wang J, Liu Y, Zhang Y, et al., 2021
- IL-17 signaling in skin repair: safeguarding metabolic adaptation of wound epithelial cells, Wang J, Ding XL, 2022
- The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling, Wang J, Cui BP, Chen ZJ, Ding XL, 2022
- Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation, Wang J, Eming SA, Ding XL, 2022
- ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli, Huang WJ, Li H, Tan WF, Wang J, 2022
- Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G, Huang W, Wang J, Liu X, Yang J, Zhang Y, et al., 2017
