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Zhen Wu
Veterinary Medicine
Sichuan Agricultural University
Sichuan
Language: Chinese, English
Antiviral
Innate Immunity
Waterfowl
Virus
Immune Response
Duck
Tembusu Virus
Interferon
Viral Infection
Immune System
Areas of Focus
- Antiviral innate immunity in waterfowl
Work Experience
- 2023-Present - Sichuan Agricultural University, College of Veterinary Medicine - Teacher
Academic Background & Achievements
- 2018-2022 PhD: Sichuan Agricultural University
- 2021-2022 Joint training: KU Leuven, Belgium
Publications
- Innate immune evasion mediated by flaviviridae non-Structural proteins, Shun Chen, Zhen Wu, Mingshu Wang, Anchun Cheng, 2017
- Duck stimulator of interferon genes plays an important role in host anti-duck plague virus infection through an IFN-dependent signalling pathway, Shun Chen, Zhen Wu, Anchun Cheng, 2017
- Binding of the Duck Tembusu Virus Protease to STING Is Mediated by NS2B and Is Crucial for STING Cleavage and for Impaired Induction of IFN-β, Zhen Wu, Anchun Cheng, Shun Chen, 2019
- The autophagy-related degradation of MDA5 by Tembusu virus nonstructural 2B disrupts IFNβproduction, Zhen Wu, Tao Hu, Anchun Cheng, Shun Chen, 2022
- The G92 NS2B mutant of Tembusu virus is involved in severe defects in progeny virus assembly, Zhen Wu, Anchun Cheng, Shun Chen, 2022
- Toll-like receptor 4 and lipopolysaccharide from commensal microbes regulate Tembusu virus infection, Zhen Wu, Anchun Cheng, Shun Chen, 2022
- Binding of Duck Tembusu virus nonstructural protein 2A to duSTING disrupts the induction of its signal transduction cascade to inhibit IFN-β induction, Wei Zhang, Zhen Wu, Anchun Cheng, Shun Chen, 2020
- The First Nonmammalian Pegivirus Demonstrates Efficient In Vitro Replication and High Lymphotropism, Zhen Wu, Yuanyuan Wu, Anchun Cheng, Shun Chen, 2020
- Emergence of a novel pegivirus species in southwest China showing a high rate of coinfection with parvovirus and circovirus in geese, Zhen Wu, Yuanyuan Wu, Anchun Cheng, Shun Chen, 2021
- The key amino acids of E protein involved in early flavivirus infection: viral entry, Tao Hu, Zhen Wu, Shun Chen, Anchun Cheng, 2021
- Substitutions at Loop Regions of TMUV E Protein Domain III Differentially Impair Viral Entry and Assembly, Tao Hu, Zhen Wu, Shun Chen, Anchun Cheng, 2021
Awards
- Sichuan Province Natural Science Second Prize - Interaction mechanism between Duck Tembusu virus and host immunity (3/5)
