Professor | Wenjin Guo | Asia Growth Partners

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Name	Wenjin Guo
Contact Information	guowenijn@jlu.edu.cn
Language ability	Chinese, English
Province	Jilin

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Name

Wenjin Guo

Contact Information

guowenijn@jlu.edu.cn

Language ability

Chinese, English

Province

Jilin

University/Lab Affiliation and Title	Jilin University
Faculty	Veterinary Medicine
Academic Background & Achievements	2012.09 - 2014.06 Bachelor in Animal Medicine, Heilongjiang Bayi Agricultural University 2014.09 - 2017.06 Master in Basic Veterinary Medicine, Heilongjiang Bayi Agricultural University 2017.09 - 2020.06 PhD in Basic Veterinary Medicine, Jilin University
Work Experience	2020.07 - 2022.07 Postdoctoral Researcher, Dingxin Scholar, Jilin University 2020.09 - Present Associate Professor, Tang Aoqing Young Scholar, Jilin University
Awards	Jilin Province Outstanding Doctoral Thesis

University/Lab Affiliation and Title

Jilin University

Faculty

Veterinary Medicine

Academic Background & Achievements

2012.09 - 2014.06 Bachelor in Animal Medicine, Heilongjiang Bayi Agricultural University
2014.09 - 2017.06 Master in Basic Veterinary Medicine, Heilongjiang Bayi Agricultural University
2017.09 - 2020.06 PhD in Basic Veterinary Medicine, Jilin University

Work Experience

2020.07 - 2022.07 Postdoctoral Researcher, Dingxin Scholar, Jilin University
2020.09 - Present Associate Professor, Tang Aoqing Young Scholar, Jilin University

Awards

Jilin Province Outstanding Doctoral Thesis

Areas of Focus	Bovine mastitis Oxidative stress Aging
Publications	Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands, Guo W, Liu J, Sun J, Gong Q, Ma H, Kan X, Cao Y, Wang J, Fu S, 2020 The inflammatory environment mediated by a high-fat diet inhibited the development of mammary glands and destroyed the tight junction in pregnant mice, Guo W, Liu J, Hou S, Hu G, Ma H, Gong Q, Kan X, Ran X, Cao Y, Wang J, Fu S, 2020 Phytic Acid Maintains the Integrity of the Blood-Milk Barrier by Regulating Inflammatory Response and Intestinal Flora Structure, Ran X, Liu J, Fu S, He F, Li K, Hu G, Guo W, 2022 The alleviating effect and mechanism of Bilobalide on ulcerative colitis, Zhang H, Wang Y, Su Y, Fang X, Guo W, 2021 GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis, Guo W, Gong Q, Zong X, Wu D, Li Y, Xiao H, Song J, Zhang S, Fu S, Feng Z, Zhuang L, 2023 GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy, Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J, 2021 Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis, Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, Cao Y, Wang J, Xu D, Ma H, Fu S, Liu J, 2019 Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway, Guo W, Liu J, Li W, Ma H, Gong Q, Kan X, Cao Y, Wang J, Fu S, 2020 Rumen-bypassed tributyrin alleviates heat stress by reducing the inflammatory responses of immune cells, Guo W, Liu J, Yang Y, Ma H, Gong Q, Kan X, Ran X, Cao Y, Wang J, Fu S, Hu G, 2021 Evodiamine Relieve LPS-Induced Mastitis by Inhibiting AKT/NF-κB p65 and MAPK Signaling Pathways, Yang Y, Ran X, Wang H, Chen Y, Hou S, Yang Z, Fu S, Liu J, Hu G, Guo W*, 2021

Areas of Focus

Bovine mastitis
Oxidative stress
Aging

Publications

Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands, Guo W, Liu J, Sun J, Gong Q, Ma H, Kan X, Cao Y, Wang J, Fu S, 2020
The inflammatory environment mediated by a high-fat diet inhibited the development of mammary glands and destroyed the tight junction in pregnant mice, Guo W, Liu J, Hou S, Hu G, Ma H, Gong Q, Kan X, Ran X, Cao Y, Wang J, Fu S, 2020
Phytic Acid Maintains the Integrity of the Blood-Milk Barrier by Regulating Inflammatory Response and Intestinal Flora Structure, Ran X, Liu J, Fu S, He F, Li K, Hu G, Guo W*, 2022
The alleviating effect and mechanism of Bilobalide on ulcerative colitis, Zhang H, Wang Y, Su Y, Fang X, Guo W*, 2021
GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis, Guo W, Gong Q, Zong X, Wu D, Li Y, Xiao H, Song J, Zhang S, Fu S, Feng Z, Zhuang L, 2023
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy, Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J, 2021
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis, Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, Cao Y, Wang J, Xu D, Ma H, Fu S, Liu J, 2019
Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway, Guo W, Liu J, Li W, Ma H, Gong Q, Kan X, Cao Y, Wang J, Fu S, 2020
Rumen-bypassed tributyrin alleviates heat stress by reducing the inflammatory responses of immune cells, Guo W, Liu J, Yang Y, Ma H, Gong Q, Kan X, Ran X, Cao Y, Wang J, Fu S, Hu G, 2021
Evodiamine Relieve LPS-Induced Mastitis by Inhibiting AKT/NF-κB p65 and MAPK Signaling Pathways, Yang Y, Ran X, Wang H, Chen Y, Hou S, Yang Z, Fu S, Liu J, Hu G, Guo W*, 2021

Dairy Cows Epithelial Cells Inflammation Cellular Mechanisms Sirt Proteins Mitochondrial Dynamics Antioxidant Defenses Nutritional Interventions Epigenetic Modifications Cellular Senescence

Ruqian Zhao - Nanjing Agricultural University

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