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Guan Zhu
Veterinary Medicine
Jilin University
Jilin
Language: English, Chinese
Zoonotic
Parasitology
Pathogens
Biochemistry
Genomics
Drug Targets
Drugs
Molecular
Interactions
Cryptosporidium
Areas of Focus
- Zoonotic Parasitology
- Pathogen Biology
- Biochemistry
- Genomics
- Drug Targets and Drugs
- Molecular Interactions
Work Experience
- 1986-1989 Assistant Researcher, Zhejiang Provincial Institute of Parasitic Diseases
- 1994-1996 Postdoctoral Researcher, Wadsworth Center, New York State Department of Health
- 1996-1999 Junior Researcher, Wadsworth Center, New York State Department of Health
- 1999-2000 Senior Researcher, Wadsworth Center, New York State Department of Health
- 2000-2005 Assistant Professor, Department of Veterinary Pathobiology, Texas A&M University
- 2005-2010 Associate Professor (Tenured), Department of Veterinary Pathobiology, Texas A&M University
- 2010-2020 Professor (Tenured), Department of Veterinary Pathobiology, Texas A&M University
- 2021-present Professor, College of Veterinary Medicine, Jilin University
Academic Background & Achievements
- 1979-1983 Bachelor of Science in Biology: Hangzhou University
- 1983-1986 Master of Science in Parasitology: Hangzhou University
- 1989-1993 PhD in Poultry Science: University of Georgia
Publications
- Cost-effective In vivo and In vitro Mouse Models for Evaluating Anti-Cryptosporidial Drug Efficacy: Assessing Vorinostat, Docetaxel and Baicalein, Liu M, Zhang D, Wang D, Wu X, Zhang Y, Yin J, Zhu G*, 2023
- On-target inhibition of Cryptosporidium parvum by nitazoxanide (NTZ) and paclitaxel (PTX) validated using a novel MDR1-transgenic host cell model and algorithms to quantify the effect on the parasite target, Yang B, Yan Y, Wang D, Zhang Y, Yin J, Zhu G, 2023
- Genomic reconstruction and features of glycosylation pathways in the apicomplexan Cryptosporidium parasites, Wang D, Wang C, Zhu G, 2022
- Discovery of New Microneme Proteins in Cryptosporidium parvum and Implication of the Roles of a Rhomboid Membrane Protein (CpROM1) in Host-Parasite Interaction, Gao X, Yin J, Wang D, Li X, Zhang Y, Wang C, Zhang Y, Zhu G, 2021
- The mucin-like, secretory type-I transmembrane glycoprotein GP900 in the apicomplexanCryptosporidium parvumis cleaved in the secretory pathway and likely plays a lubrication role, Li X, Yin J, Wang D, Gao X, Zhang Y, Wu M, Zhu G, 2022
- A Single-Pass Type I Membrane Protein from the Apicomplexan ParasiteCryptosporidium parvumwith Nanomolar Binding Affinity to Host Cell Surface, Zhang T, Gao X, Wang D, Zhao J, Zhang N, Li Q, Zhu G, Yin J*, 2021
- Implication of Potential Differential Roles of the Two Phosphoglucomutase Isoforms in the Protozoan ParasiteCryptosporidium parvum, Nie J, Yin J, Wang D, Wang C, Zhu G, 2021
- Current status and challenges in drug discovery against the globally important zoonotic cryptosporidiosis, Zhu G, Yin J, Cuny GD, 2021
Awards
- 2017: Zoetis Award for Veterinary Research Excellence
