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Qiaoran Xi
Life Science
Tsinghua University
Beijing
Language: English, Chinese
Cell Biology
Biochemistry
Molecular Biology
Genomics
Tgf-Beta
Signaling
Embryonic Stem Cells
Self-Renewal
Embryonic Development
Cancer
Areas of Focus
- Cell biology, biochemistry, molecular biology, genomics
- TGF-beta signaling in embryonic stem cell self-renewal, embryonic development, and cancer
Work Experience
- 2004-2005 - New York University Medical School - Postdoctoral Researcher
- 2006-2013 - Sloan Kettering Cancer Center - Postdoctoral Researcher
- 2013-present - Tsinghua University - Assistant Professor, Associate Professor
Academic Background & Achievements
- 1989-1993 Bachelor: Nanjing University, Biochemistry
- 1998-2004 PhD: New York University Medical School
- Postdoctoral Research: New York University Medical School, Sloan Kettering Cancer Center
Publications
- Fimepinostat impairs NFκB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma, Wang D, Yan K, Yu H, Li H, Zhou W, Hong Y, Guo S, Wang Y, Xu Chen, Pan C, Tang Y, Liu N, Wu W, Zhang L, Xi Q, 2024
- BMP signaling in cancer stemness and differentiation, Zhou W, Yan K, Xi Q, 2023
- Recruitment of TRIM33 to cell‐context specific PML nuclear bodies regulates nodal signaling in mESCs, Sun H, Chen Y, Yan K, Shao Y, Zhang Q, Lin Y, Xi Q, 2023
- LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells, Kong X, Yan K, Deng P, Fu H, Sun H, Huang W, Jiang S, Dai J, Zhang Q, Liu J, Xi Q, 2022
- Context-dependent tumor suppressive BMP signaling in Diffuse Intrinsic Pontine Glioma regulates stemness through epigenetic regulation of CXXC5, Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y, Shan S, Zhang Q, Tang Y, Zhang L, Xi Q, 2022
- HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs, Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q, 2022
- A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells, Fu H, Wang T, Kong X, Yan K, Yang Y, Cao J, Yuan Y, Wang N, Kee K, Lu Z, Xi Q, 2022
- A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells, Zuo F, Jiang J, Fu H, Yan K, Liefke R, Zhang J, Hong Y, Chang Z, Liu N, Wang Z, Xi Q, 2022
- H3K18ac primes mesendodermal differentiation upon nodal signaling, Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, Sun Y, Xu X, Song Z, Yang Y, Massagué J, Lan X, Lu Z, Chen YG, Deng H, Xie W, Xi Q, 2019
- Potent anti-tumor efficacy of palbociclib in H3.3K27M-mutant diffuse intrinsic pontine glioma, Sun Y, Sun Y, Yan K, Li Z, Xu C, Geng Y, Pan C, Chen X, Zhang l, Xi Q, 2019
- The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin, Tian W, Yan P, Xu N, Chakravorty A, Liefke R, Xi Q, Wang Z, 2019
- Crosstalk between TGF-β signaling and epigenome, Bai J, Xi Q, 2018
- Role of TRIM33 in Wnt signaling during mesendoderm differentiation, Xia X, Zuo F, Luo M, Sun Y, Bai J, Xi Q, 2017
- TGF-β control of stem cell differentiation genes, Massagué J, Xi Q, 2012
- A poised chromatin platform for TGFβ access to master regulators, Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang L, Liu JX, Kim H, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J, 2011
