Professor | Ning Yan | Asia Growth Partners

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Name	Ning Yan
Contact Information	{'en': 'Phone: +86-10-62771298 (Lab)\\nE-mail: nyan(at)tsinghua.edu.cn', 'zh': '电话：+86-10-62771298（实验室）\\n电子邮件：nyan(at)tsinghua.edu.cn', 'de': 'Telefon: +86-10-62771298 (Labor)\\nE-Mail: nyan(at)tsinghua.edu.cn'}
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Ning Yan

Contact Information

{'en': 'Phone: +86-10-62771298 (Lab)\\nE-mail: nyan(at)tsinghua.edu.cn', 'zh': '电话：+86-10-62771298（实验室）\\n电子邮件：nyan(at)tsinghua.edu.cn', 'de': 'Telefon: +86-10-62771298 (Labor)\\nE-Mail: nyan(at)tsinghua.edu.cn'}

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1996-2000 Bachelor of Biological Sciences and Technology: Tsinghua University 2000-2004 PhD in Molecular Biology: Princeton University
Work Experience	2005-2007 Postdoctoral Researcher, Department of Molecular Biology, Princeton University 2007-2017 Professor and Doctoral Supervisor, School of Medicine and Life Sciences, Tsinghua University 2017-2022 Shirley Tilghman Endowed Chair Professor, Department of Molecular Biology, Princeton University; Adjunct Professor, Department of Chemistry 2022-present Professor and Doctoral Supervisor, School of Life Sciences, Tsinghua University

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1996-2000 Bachelor of Biological Sciences and Technology: Tsinghua University
2000-2004 PhD in Molecular Biology: Princeton University

Work Experience

2005-2007 Postdoctoral Researcher, Department of Molecular Biology, Princeton University
2007-2017 Professor and Doctoral Supervisor, School of Medicine and Life Sciences, Tsinghua University
2017-2022 Shirley Tilghman Endowed Chair Professor, Department of Molecular Biology, Princeton University; Adjunct Professor, Department of Chemistry
2022-present Professor and Doctoral Supervisor, School of Life Sciences, Tsinghua University

Areas of Focus	Structure and function of membrane transport proteins related to diseases Structure and mechanism of voltage-gated ion channels Regulatory mechanisms of cholesterol metabolism
Publications	Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels, Nieng Yan et al., 2022 Structure of human Cav2.2 channel blocked by the painkiller ziconotide, Nieng Yan et al., 2021 Structural basis for catalysis and substrate specificity of human ACAT1, Nieng Yan et al., 2020 Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins, Nieng Yan et al., 2019 Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1, Nieng Yan et al., 2018 Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution, Nieng Yan et al., 2017 Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2, Nieng Yan et al., 2016 Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution, Nieng Yan et al., 2016 Structure of the voltage-gated calcium channel Cav1.1 complex, Nieng Yan et al., 2015 Molecular basis of ligand recognition and transport by glucose transporters, Nieng Yan et al., 2015 Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution, Nieng Yan et al., 2015 Crystal structure of the human glucose transporter GLUT1, Nieng Yan et al., 2014 Crystal structure of a bacterial homologue of glucose transporters GLUT1-4, Nieng Yan et al., 2012 Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel, Nieng Yan et al., 2012 Structure of a fucose transporter in an outward-open conformation, Nieng Yan et al., 2010

Areas of Focus

Structure and function of membrane transport proteins related to diseases
Structure and mechanism of voltage-gated ion channels
Regulatory mechanisms of cholesterol metabolism

Publications

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels, Nieng Yan et al., 2022
Structure of human Cav2.2 channel blocked by the painkiller ziconotide, Nieng Yan et al., 2021
Structural basis for catalysis and substrate specificity of human ACAT1, Nieng Yan et al., 2020
Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins, Nieng Yan et al., 2019
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1, Nieng Yan et al., 2018
Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution, Nieng Yan et al., 2017
Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2, Nieng Yan et al., 2016
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution, Nieng Yan et al., 2016
Structure of the voltage-gated calcium channel Cav1.1 complex, Nieng Yan et al., 2015
Molecular basis of ligand recognition and transport by glucose transporters, Nieng Yan et al., 2015
Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution, Nieng Yan et al., 2015
Crystal structure of the human glucose transporter GLUT1, Nieng Yan et al., 2014
Crystal structure of a bacterial homologue of glucose transporters GLUT1-4, Nieng Yan et al., 2012
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel, Nieng Yan et al., 2012
Structure of a fucose transporter in an outward-open conformation, Nieng Yan et al., 2010

Membrane Transport Protein Structure Disease Correlation Ion Channels Voltage-Gated Cholesterol Metabolism Biochemistry Structural Biology Molecular Biology

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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