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Guo-Qiang Chen
Life Science
Tsinghua University
Beijing
Language: English, Chinese, German
Synthetic
Biology
Microbial
Metabolic
Engineering
Biomaterials
Industrial
Biotechnology
Production
Design
Areas of Focus
- Synthetic Biology
- Microbial Metabolic Engineering
- Biomaterials
- Industrial Biotechnology
Work Experience
- 1994-1997 Associate Professor, School of Life Sciences, Tsinghua University
- 1997-present Professor, School of Life Sciences, Tsinghua University
Academic Background & Achievements
- 1981-1985 Bachelor: South China University of Technology
- 1986-1989 PhD: Graz University of Technology, Austria
- 1990-1992 Postdoctoral: University of Nottingham, UK
- 1992-1994 Postdoctoral: University of Alberta, Canada
Publications
- Production of PHA copolymers consisting of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx) by recombinant Halomonas bluephagenesis, Guo-Qiang Chen et al., 2023
- Tailor-Made Polyhydroxyalkanoates by Reconstructing Pseudomonas Entomophila, Guo-Qiang Chen et al., 2021
- Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis, Guo-Qiang Chen et al., 2021
- Ketone body 3-hydroxybutyrate ameliorates atherosclerosis via receptor Gpr109a-mediated calcium influx, Guo-Qiang Chen et al., 2021
- Rational flux-tuning of Halomonas bluephagenesis for co-production of bioplastic PHB and ectoine, Guo-Qiang Chen et al., 2020
- Synthetic biology of extremophiles: a new wave of biomanufacturing, Guo-Qiang Chen et al., 2023
- PHB production from food waste hydrolysates by Halomonas bluephagenesis Harboring PHB operon linked with an essential gene, Guo-Qiang Chen et al., 2023
- 3-Hydroxybutyrate ameliorates insulin resistance by inhibiting PPARγ Ser273 phosphorylation in type 2 diabetic mice, Guo-Qiang Chen et al., 2023
- Engineering an oleic acid-induced system for Halomonas, E. coli and Pseudomonas, Guo-Qiang Chen et al., 2022
- Porous Polydroxyalkanoates (PHA) Scaffolds with Antibacterial Property for Oral Soft Tissue Regeneration, Guo-Qiang Chen et al., 2022
- Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli, Guo-Qiang Chen et al., 2021
- Engineering the permeability of Halomonas bluephagenesis enhanced its chassis properties, Guo-Qiang Chen et al., 2021
- Biosynthesis of functional polyhydroxyalkanoates by engineered Halomonas bluephagenesis, Guo-Qiang Chen et al., 2020
- Stimulus response-based fine-tuning of polyhydroxyalkanoate pathway in Halomonas, Guo-Qiang Chen et al., 2019
- Chromosome engineering of the TCA cycle in Halomonas bluephagenesis for production of copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate (PHBV), Guo-Qiang Chen et al., 2019
Awards
- 2023 International Metabolic Engineering Award
- 2022 Natural Resource Science and Technology Award
- 2021 Jilin Province Science and Technology Award, First Prize
- 2012 Beijing Science and Technology Award, Second Prize
- 2002 National Technology Invention, Second Prize
